Zobrazeno 1 - 10
of 293
pro vyhledávání: '"H. Handler"'
Autor:
Eric W. Prince, Ros Whelan, David M. Mirsky, Nicholas Stence, Susan Staulcup, Paul Klimo, Richard C. E. Anderson, Toba N. Niazi, Gerald Grant, Mark Souweidane, James M. Johnston, Eric M. Jackson, David D. Limbrick, Amy Smith, Annie Drapeau, Joshua J. Chern, Lindsay Kilburn, Kevin Ginn, Robert Naftel, Roy Dudley, Elizabeth Tyler-Kabara, George Jallo, Michael H. Handler, Kenneth Jones, Andrew M. Donson, Nicholas K. Foreman, Todd C. Hankinson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Deep learning (DL) is a widely applied mathematical modeling technique. Classically, DL models utilize large volumes of training data, which are not available in many healthcare contexts. For patients with brain tumors, non-invasive diagnosi
Externí odkaz:
https://doaj.org/article/48a196a679684d488c084efeeb434cda
Autor:
Eric Prince, Ros Whelan, Andrew Donson, Susan Staulcup, Astrid Hengartner, Trinka Vijmasi, Chibueze Agwu, Kevin O. Lillehei, Nicholas K. Foreman, James M. Johnston, Luca Massimi, Richard C. E. Anderson, Mark M. Souweidane, Robert P. Naftel, David D. Limbrick, Gerald Grant, Toba N. Niazi, Roy Dudley, Lindsay Kilburn, Eric M. Jackson, George I. Jallo, Kevin Ginn, Amy Smith, Joshua J. Chern, Amy Lee, Annie Drapeau, Mark D. Krieger, Michael H. Handler, Todd C. Hankinson, on behalf of the Advancing Treatment for Pediatric Craniopharyngioma Consortium
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract Adamantinomatous craniopharyngioma (ACP) is a biologically benign but clinically aggressive lesion that has a significant impact on quality of life. The incidence of the disease has a bimodal distribution, with peaks occurring in children an
Externí odkaz:
https://doaj.org/article/a32c5645c0614369aacbf5d325ac568d
Autor:
Austin E. Gillen, Kent A. Riemondy, Vladimir Amani, Andrea M. Griesinger, Ahmed Gilani, Sujatha Venkataraman, Krishna Madhavan, Eric Prince, Bridget Sanford, Todd C. Hankinson, Michael H. Handler, Rajeev Vibhakar, Ken L. Jones, Siddhartha Mitra, Jay R. Hesselberth, Nicholas K. Foreman, Andrew M. Donson
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108023- (2020)
Summary: Ependymoma (EPN) is a brain tumor commonly presenting in childhood that remains fatal in most children. Intra-tumoral cellular heterogeneity in bulk-tumor samples significantly confounds our understanding of EPN biology, impeding development
Externí odkaz:
https://doaj.org/article/86aaa43b961a406abbb08113d63ce8d6
Autor:
Megan M, Finneran, Sarah, Graber, Kim, Poppleton, Allyson L, Alexander, C Corbett, Wilkinson, Brent R, O'Neill, Todd C, Hankinson, Michael H, Handler
Publikováno v:
Journal of Neurosurgery: Pediatrics. 30:602-608
OBJECTIVE Prior to 2019, the majority of patients at Children’s Hospital Colorado were admitted to the pediatric intensive care unit (PICU) following Chiari malformation (CM) decompression surgery. This study sought to identify the safety and effic
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Consensus NMF of 81 primary ependymoma samples at k = 3 delineates two posterior fossa subgroups in the study cohort.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5d4b4de8cf0516633c49ed30cddeae6
https://doi.org/10.1158/2326-6066.22538356
https://doi.org/10.1158/2326-6066.22538356
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Supplemental Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04baa86546daacfbe8b5565aecd3313f
https://doi.org/10.1158/2326-6066.22538359
https://doi.org/10.1158/2326-6066.22538359
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
STAT3, IL-6 and inflammatory response pathway signaling associated gene expression is upregulated in Group A EPN.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8841ed33a212e3d2ce4d8f15e1dd8b
https://doi.org/10.1158/2326-6066.22538353
https://doi.org/10.1158/2326-6066.22538353
Supplementary Figure 1 from Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors
Autor:
Andrew Thorburn, Nicholas K. Foreman, Michael H. Handler, David M. Mirsky, Michael J. Morgan, Diane K. Birks, Andrew M. Donson, Vladimir Amani, Andrea M. Griesinger, Joshua C. Thompson, Jean M. Mulcahy Levy
PDF file 98K, Microscopy data with representative photos and quantification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f286958136ec88f0f29364d15ca0a4
https://doi.org/10.1158/2159-8290.22530806
https://doi.org/10.1158/2159-8290.22530806
Autor:
Nicholas K. Foreman, Rajeev Vibhakar, Michael H. Handler, Phillip Reigan, Steffanie L. Furtek, Lindsey M. Hoffman, Diane K. Birks, Vladimir Amani, Jean M. Mulcahy Levy, Andrew M. Donson, Rebecca J. Josephson, Andrea M. Griesinger
Experimentally determined STAT3 upregulated genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecc3d7b05a865dcb42cb4842888f2d8
https://doi.org/10.1158/2326-6066.22538338
https://doi.org/10.1158/2326-6066.22538338
Supplementary Figure 5 from Autophagy Inhibition Improves Chemosensitivity in BRAFV600E Brain Tumors
Autor:
Andrew Thorburn, Nicholas K. Foreman, Michael H. Handler, David M. Mirsky, Michael J. Morgan, Diane K. Birks, Andrew M. Donson, Vladimir Amani, Andrea M. Griesinger, Joshua C. Thompson, Jean M. Mulcahy Levy
PDF file 31K, Autophagic flux by flow cytometry in vemurafenib treated cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381edd6b40b61d913557eb8caebb5438
https://doi.org/10.1158/2159-8290.22530794.v1
https://doi.org/10.1158/2159-8290.22530794.v1