Zobrazeno 1 - 10 of 45 pro vyhledávání: '"H. H. Watzke"'
1
Coagulation Factors II, V, VII, and X, Prothrombin Gene 20210G→A Transition, and Factor V Leiden in Coronary Artery Disease
Autor: Bernhard Lämmle, Bernd R. Binder, Irmela Sulzer, B. Stucki, Miha Furlan, H. H. Watzke, Maurice Redondo, F. Demarmels Biasiutti, Walter A. Wuillemin
Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 19:1020-1025
Abstract —Increased levels of hemostatic factors and genetic mutations of proteins involved in coagulation may play a role in the pathogenesis of coronary artery disease. We investigated clotting activity of factors II (FII:C), V (FV:C), VII (FVII:
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac0a6d66354454ade145313adc80572
https://doi.org/10.1161/01.atv.19.4.1020
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2
Factor X Frankfurt I
Autor: H H Watzke, P L Turecek, I M Nöbauer-Huhmann, I Scharrer, B. Krinninger, W Höller, G Richter, E Forberg
Publikováno v: Blood Coagulation & Fibrinolysis. 9:143-152
A family with hereditary factor X deficiency is presented. One member, a 25-year-old man, showed a mild bleeding tendency. His factor X activity (extrinsic: 56%; intrinsic: 55%; Russell's viper venom: 57%) and his level of circulating factor X antige
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9626a04521c4462b8d16743e7261f3e
https://doi.org/10.1097/00001721-199803000-00005
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3
Molekularbiologische Grundlagen des Faktor-X-Mangels
Autor: H. H. Watzke
Publikováno v: Hämostaseologie. 14:190-194
ZusammenfassungFaktor X ist ein Vitamin-K-abhängiges Plasmaprotein, das eine zentrale Stellung in der Blutgerinnung einnimmt. Durch Interaktionen mit Faktor Vlla/Gewebsfaktor und Faktor IXa/FVIlia wird das Proenzym FXzum Enzym Faktor Xa aktiviert. F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c3127386c0b6f3c4597f80997fa4eb56
https://doi.org/10.1055/s-0038-1660363
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4
Molekularbiologische Grundlagen und Diagnostik der Hämophilie B
Autor: H. H. Watzke
Publikováno v: Hämostaseologie. 14:176-183
ZusammenfassungDie Hämophilie B beruht auf einer verminderten plasmatischen Gerinnungsaktivität von Faktor IX. Dieser Defekt ist entweder durch eine verminderte Produktion von Faktor IX bedingt oder geht auf ein funktionell defektes oder auch insta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84540f427421d71a16871ae127291c2d
https://doi.org/10.1055/s-0038-1660361
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5
Human coagulation factor X deficiency caused by a mutant signal peptide that blocks cleavage by signal peptidase but not targeting and translocation to the endoplasmic reticulum
Autor: Katherine A. High, Mark O. Lively, H H Watzke, Marco Racchi
Publikováno v: Journal of Biological Chemistry. 268:5735-5740
Human factor XSanto Domingo is a form of coagulation factor X in which a mutation within the signal peptide region of the precursor protein has been correlated genetically with a severe deficiency of factor X in the affected individual. A point mutat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3da986b776fcb2dca8c42e2379cdf3f8
https://doi.org/10.1016/s0021-9258(18)53380-9
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7
The decanucleotide polymorphism in the factor VII promoter predicts factor VII plasma levels but not the risk of acute coronary syndromes
Autor: E, Jimenez-Boj, J, Schüttrumpf, E, Forberg, H H, Watzke, K, Huber
Publikováno v: Journal of thrombosis and thrombolysis. 10(1)
It is known from large epidemiological studies that the elevation of coagulation factor VII in plasma is an independent risk factor for acute coronary syndromes. The level of factor VII is influenced by polymorphic sites in the factor VII gene. Howev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::29b5140e5ca01509bae808b7b77eafcc
https://pubmed.ncbi.nlm.nih.gov/10947911
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8
A prospective controlled trial comparing weekly self-testing and self-dosing with the standard management of patients on stable oral anticoagulation
Autor: H H, Watzke, E, Forberg, G, Svolba, E, Jimenez-Boj, B, Krinninger
Publikováno v: Thrombosis and haemostasis. 83(5)
Oral anticoagulant therapy requires frequent laboratory controls of its intensity to assure therapeutic efficacy and to prevent potentially life threatening adverse events. It is generally assumed, that increasing the frequency of testing would lead
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9649e653601c342ac945fa7d92e0809f
https://pubmed.ncbi.nlm.nih.gov/11127888
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9
Oral anticoagulation after a first episode of venous thromboembolism: how long? How strong?
Autor: H H, Watzke
Publikováno v: Thrombosis and haemostasis. 82
A number of studies have been published in the last years which shed light on the optimal intensity and the optimal duration of oral anticoagulation in patients with venous thrombosis. Based on these studies it is now generally recommended to treat p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c9f19251c0690d4ca63c3643939d67b
https://pubmed.ncbi.nlm.nih.gov/10695502
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10
Genetic control of hemostatic factors in relation to atherosclerosis
Autor: H. H. Watzke, J. Schüttrumpf
Publikováno v: From Molecule to Men ISBN: 9783642633386
Increased levels of coagulation factors VII and fibrinogen were identified as risk factors for acute coronary syndromes many years ago. Analysis of the genes coding for these proteins suggest a genetic component in the determination of their plasma l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::551ace4483a59c839e9f6b707ccae9f4
https://doi.org/10.1007/978-3-642-57724-6_15
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