Zobrazeno 1 - 10
of 664
pro vyhledávání: '"H. Großmann"'
Autor:
Eric A. Smith, Rachel L. Belote, Nelly M. Cruz, Tarek E. Moustafa, Carly A. Becker, Amanda Jiang, Shukran Alizada, Anastasia Prokofyeva, Tsz Yin Chan, Tori A. Seasor, Michael Balatico, Emilio Cortes-Sanchez, David H. Lum, John R. Hyngstrom, Hanlin Zeng, Dekker C. Deacon, Allie H. Grossmann, Richard M. White, Thomas A. Zangle, Robert L. Judson-Torres
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background Acral melanoma (AM) is an aggressive melanoma variant that arises from palmar, plantar, and nail unit melanocytes. Compared to non-acral cutaneous melanoma (CM), AM is biologically distinct, has an equal incidence across genetic a
Externí odkaz:
https://doaj.org/article/8b977080f96146e9924ad02dec9ceb6c
Autor:
Yinshen Wee, Junhua Wang, Emily C. Wilson, Coulson P. Rich, Aaron Rogers, Zongzhong Tong, Evelyn DeGroot, Y. N. Vashisht Gopal, Michael A. Davies, H. Atakan Ekiz, Joshua K. H. Tay, Chris Stubben, Kenneth M. Boucher, Juan M. Oviedo, Keke C. Fairfax, Matthew A. Williams, Sheri L. Holmen, Roger K. Wolff, Allie H. Grossmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Tumour-host immune interactions lead to complex changes in the tumour microenvironment (TME), impacting progression, metastasis and response to therapy. While it is clear that cancer cells can have the capacity to alter immune landscapes, ou
Externí odkaz:
https://doaj.org/article/e7e3f29dc417478dac14dd2ee69fe482
Autor:
Sheri L. Holmen, Matthew W. VanBrocklin, Michelle C. Mendoza, Michael A. Davies, Martin McMahon, Kenneth M. Boucher, Keith L. Duffy, Allie H. Grossmann, Sean C. Strain, Christopher M. Stehn, Stephanie N. Angel, Grant M. Fischer, Gennie L. Parkman, Mark R. Silvis, Kirby A. Trombetti, David A. Kircher
Supplementary Table 1. Summary of tumor formation in Dct::TVA mice. .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3017ffd947ea0fe45b16e31e2e6d917e
https://doi.org/10.1158/1541-7786.22514928.v1
https://doi.org/10.1158/1541-7786.22514928.v1
Autor:
Sheri L. Holmen, Matthew W. VanBrocklin, Michelle C. Mendoza, Michael A. Davies, Martin McMahon, Kenneth M. Boucher, Keith L. Duffy, Allie H. Grossmann, Sean C. Strain, Christopher M. Stehn, Stephanie N. Angel, Grant M. Fischer, Gennie L. Parkman, Mark R. Silvis, Kirby A. Trombetti, David A. Kircher
Supplementary Figure 6. Expression of AKT1E17K promotes the dysregulation of integrins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9454b5a10eb9a2a4fe403f92b1302221
https://doi.org/10.1158/1541-7786.22514937
https://doi.org/10.1158/1541-7786.22514937
Autor:
Sheri L. Holmen, Matthew W. VanBrocklin, Michelle C. Mendoza, Michael A. Davies, Martin McMahon, Kenneth M. Boucher, Keith L. Duffy, Allie H. Grossmann, Sean C. Strain, Christopher M. Stehn, Stephanie N. Angel, Grant M. Fischer, Gennie L. Parkman, Mark R. Silvis, Kirby A. Trombetti, David A. Kircher
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032b32ea8a6305ee92a068d90d7dffaa
https://doi.org/10.1158/1541-7786.22514931
https://doi.org/10.1158/1541-7786.22514931
Autor:
Allie H. Grossmann, Sheri L. Holmen, Dean Y. Li, Shannon J. Odelberg, Andrea Bild, David A. Kircher, Coulson P. Rich, Donghan Shin, Tara Mleynek, Roger K. Wolff, Lise K. Sorensen, Jingfu Peng, Aaron Rogers, Lehi Acosta-Alvarez, Samuel W. Brady, Jae Hyuk Yoo
Figure S4. Primary tumor incidence, growth, survival and metastasis in Ptenf/f vs. Arf6Q67L mice. (a) Increased tumor incidence (% = # of mice that developed a tumor / # TVA positive, injected mice) in Ptenf/f vs. Arf6Q67L cohorts. Fisher's exact tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9def0b48b2cc83022bfecdb8248f0a63
https://doi.org/10.1158/0008-5472.22420623
https://doi.org/10.1158/0008-5472.22420623
Autor:
Allie H. Grossmann, Sheri L. Holmen, Dean Y. Li, Shannon J. Odelberg, Andrea Bild, David A. Kircher, Coulson P. Rich, Donghan Shin, Tara Mleynek, Roger K. Wolff, Lise K. Sorensen, Jingfu Peng, Aaron Rogers, Lehi Acosta-Alvarez, Samuel W. Brady, Jae Hyuk Yoo
Melanoma has an unusual capacity to spread in early-stage disease, prompting aggressive clinical intervention in very thin primary tumors. Despite these proactive efforts, patients with low-risk, low-stage disease can still develop metastasis, indica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfbd622d715707efdee9a96edeca39d
https://doi.org/10.1158/0008-5472.c.6510696
https://doi.org/10.1158/0008-5472.c.6510696
Autor:
Allie H. Grossmann, Sheri L. Holmen, Dean Y. Li, Shannon J. Odelberg, Andrea Bild, David A. Kircher, Coulson P. Rich, Donghan Shin, Tara Mleynek, Roger K. Wolff, Lise K. Sorensen, Jingfu Peng, Aaron Rogers, Lehi Acosta-Alvarez, Samuel W. Brady, Jae Hyuk Yoo
Table S1: ARF6 pathways and related genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e3cad3eebeb5fc43555cf8b0b5bcb1b
https://doi.org/10.1158/0008-5472.22420611
https://doi.org/10.1158/0008-5472.22420611
Autor:
Joseph H. Cho, James P. Robinson, Rowan A. Arave, William J. Burnett, David A. Kircher, Guo Chen, Michael A. Davies, Allie H. Grossmann, Matthew W. VanBrocklin, Martin McMahon, Sheri L. Holmen
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 898-905 (2015)
Metastases are the major cause of melanoma-related mortality. Previous studies implicating aberrant AKT signaling in human melanoma metastases led us to evaluate the effect of activated AKT1 expression in non-metastatic BRAFV600E/Cdkn2aNull mouse mel
Externí odkaz:
https://doaj.org/article/4e2c49c5716c454581ddfb0df503505a
Autor:
Emily C Wilson, Yinshen Wee, Junhua Wang, Coulson P Rich, Aaron Rogers, Roger K Wolff, Sheri L Holmen, Allie H Grossmann
Publikováno v:
Cancer Immunology Research. 10:B50-B50
Although immune checkpoint blockade (ICB) therapy can improve outcomes in advanced melanoma, early detection and treatment focused on preventing metastasis remain the optimal approaches for superior survival. Immune evasion occurs early in melanoma d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43154292d546b6fe77e21f44aaa1432d
https://doi.org/10.1158/2326-6074.tumimm22-b50
https://doi.org/10.1158/2326-6074.tumimm22-b50