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Structural failures in refrofit historical murat masonry arch bridge

Autor: Murat Karacasu, Hakan Ozbasaran, Mizam Dogan, H. Gonen, Hande Gökdemir

Publikováno v: Engineering Failure Analysis. 35:334-342

In this study, after giving short information about historical bridges, finite element model of Palu Bridge, which is located near the Palu county of Elazig province, is generated with SAP2000. Deformations and stresses of the bridge are determined u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5a6c57d373a5a6734c7334df78b5ba96
https://doi.org/10.1016/j.engfailanal.2013.02.024

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Conference

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Conference

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Conference

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Isolation, characterization, and partial purification of a novel ubiquitin-protein ligase, E3. Targeting of protein substrates via multiple and distinct recognition signals and conjugating enzymes

Autor: H, Gonen, I, Stancovski, D, Shkedy, T, Hadari, B, Bercovich, E, Bengal, S, Mesilati, O, Abu-Hatoum, A L, Schwartz, A, Ciechanover

Publikováno v: The Journal of biological chemistry. 271(1)

Degradation of a protein via the ubiquitin system involves two discrete steps, conjugation of ubiquitin to the substrate and degradation of the adduct. Conjugation follows a three-step mechanism. First, ubiquitin is activated by the ubiquitin-activat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::45e3029410efe602f34a7086d39b0e56
https://pubmed.ncbi.nlm.nih.gov/8550577

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Protein synthesis elongation factor EF-1 alpha is an isopeptidase essential for ubiquitin-dependent degradation of certain proteolytic substrates

Autor: H, Gonen, D, Dickman, A L, Schwartz, A, Ciechanover

Publikováno v: Advances in experimental medicine and biology. 389

Targeting of different cellular proteins for conjugation and subsequent degradation via the ubiquitin pathway involves diverse recognition signals and distinct enzymatic factors. A few proteins are recognized via their N-terminal amino acid residue a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::30b589cbaef8b7555e30251646d64b90
https://pubmed.ncbi.nlm.nih.gov/8861013

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Purification and characterization of a novel species of ubiquitin-carrier protein, E2, that is involved in degradation of non-'N-end rule' protein substrates

Autor: N, Blumenfeld, H, Gonen, A, Mayer, C E, Smith, N R, Siegel, A L, Schwartz, A, Ciechanover

Publikováno v: The Journal of biological chemistry. 269(13)

Ubiquitin-carrier proteins (E2s, ubiquitin-conjugating enzymes, UBCs) participate in proteolysis by catalyzing transfer of activated ubiquitin to the protein substrates, which are bound to specific ubiquitin-protein ligases (E3s). Yeast UBC2 (RAD6) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::721ec5906f4554f8c471dedff93195f4
https://pubmed.ncbi.nlm.nih.gov/8144544

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The ubiquitin-mediated proteolytic pathway: enzymology and mechanisms of recognition of the proteolytic substrates

Autor: A, Ciechanover, H, Gonen

Publikováno v: Seminars in cell biology. 1(6)

Degradation of proteins by the ubiquitin system involves two discrete steps. Initially, ubiquitin is covalently linked in an ATP-dependent mode to the protein substrate. The protein moiety of the conjugate is subsequently degraded by a specific prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5d921cf71a8d12cd023a732c1f9f3848
https://pubmed.ncbi.nlm.nih.gov/1966527

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Degradation of proteins by the ubiquitin-mediated proteolytic pathway

Autor: A, Ciechanover, H, Gonen, S, Elias, A, Mayer

Publikováno v: The New biologist. 2(3)

Degradation of a protein by the ubiquitin system involves two distinct processes. In the first step, ubiquitin is covalently linked in an ATP-dependent mode to the protein substrate. The protein moiety of the conjugate is then degraded by a specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d131d0444d4f77482df6582553e8b641
https://pubmed.ncbi.nlm.nih.gov/2177651

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