Zobrazeno 1 - 10
of 14
pro vyhledávání: '"H. G. Shertzer"'
Publikováno v:
Toxicology Mechanisms and Methods. 13:21-29
It is necessary to determine whether chemicals or drugs have the potential to pose a threat to human health. Chemicals that can damage DNA are detected in short-term assays, but the detection of nongenotoxic carcinogens relies upon bioassays in labor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::393b02361e0d90e83b8950d40e55d284
https://doi.org/10.1080/15376510309823
https://doi.org/10.1080/15376510309823
Autor:
P. Dibello, H. G. Shertzer, S. Mahajan, Donald W. Jacobsen, P. N. M. Nair, U. J. Dumaswala, L. Zhuo
Publikováno v:
American Journal of Physiology-Cell Physiology. 280:C867-C873
Oxidant stress, in vivo or in vitro, is known to induce oxidative changes in human red blood cells (RBCs). Our objective was to examine the effect of augmenting RBC glutathione (GSH) synthesis on 1) degenerative protein loss and 2) RBC chemokine- and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e133fe60f37cf80a02095fb47bd91
https://doi.org/10.1152/ajpcell.2001.280.4.c867
https://doi.org/10.1152/ajpcell.2001.280.4.c867
Autor:
A P Senft, H G Shertzer
Publikováno v:
Drug Metabolism and Drug Interactions. 17
This review provides a historical perspective for the development of indole-3-carbinol (I-3-C) as a chemopreventive or therapeutic agent. Early experiments in animal models clearly showed that feeding cruciferous vegetables reduced the incidence of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2d7fbb5505d658def902237847c8de
https://doi.org/10.1515/dmdi.2000.17.1-4.159
https://doi.org/10.1515/dmdi.2000.17.1-4.159
Autor:
R M, Liu, V, Vasiliou, H, Zhu, J L, Duh, M W, Tabor, A, Puga, D W, Nebert, M, Sainsbury, H G, Shertzer
Publikováno v:
Carcinogenesis. 15(10)
The murine aromatic hydrocarbon ([Ah]) gene battery consists of at least six genes that code for two functionalizing (Phase I) enzymes and four non-functionalizing (Phase II) enzymes. These enzymes are induced by compounds such as aromatic hydrocarbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc3d32e96e56283d2077e72761aea939
https://pubmed.ncbi.nlm.nih.gov/7955076
https://pubmed.ncbi.nlm.nih.gov/7955076
Publikováno v:
Advances in experimental medicine and biology. 283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70caa2648f93a1bd498ec751913f1f8d
https://pubmed.ncbi.nlm.nih.gov/2069064
https://pubmed.ncbi.nlm.nih.gov/2069064
Publikováno v:
Advances in experimental medicine and biology. 283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::907cbdf914f2c17d320784529a2b0e88
https://pubmed.ncbi.nlm.nih.gov/2069062
https://pubmed.ncbi.nlm.nih.gov/2069062
Publikováno v:
Advances in experimental medicine and biology. 197
Free radicals mediate toxicological and carcinogenic responses of tissues to many chemicals. Cellular defenses against radical mediated damage utilize endogenous substances such as tocopherol, ascorbate and GSH. Here we report a new antioxidant, indo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a81627ad9f10b2fcb90417d1632f446
https://pubmed.ncbi.nlm.nih.gov/3766267
https://pubmed.ncbi.nlm.nih.gov/3766267
Autor:
H G, Shertzer, E, Racker
Publikováno v:
The Journal of biological chemistry. 249(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::66bab9a9bcb4f2fe68535480889a54d0
https://pubmed.ncbi.nlm.nih.gov/4814345
https://pubmed.ncbi.nlm.nih.gov/4814345
Autor:
H. G. Shertzer, M. W. Tabor
Publikováno v:
Journal of applied toxicology : JAT. 8(2)
A novel assay system was developed in order to quantitate the nucleophilicity of pure chemicals or tissue extracts. This Nucleophilic Index Value (NIV) assay was based on the ability of putative nucleophiles to inhibit the methylation of cysteine by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1f3606e9977d8438fa5f3c3318607d
https://pubmed.ncbi.nlm.nih.gov/3379233
https://pubmed.ncbi.nlm.nih.gov/3379233
Publikováno v:
Drug-nutrient interactions. 5(4)
Carbon tetrachloride-mediated hepatotoxicity in mice was influenced by two standard, commercially available diets and by a corn oil treatment vehicle. Animals maintained on Purina 5001 diet were less sensitive than animals maintained on Teklad LM-485
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e3c2aec11daa7f1223b17f44e442d8c2
https://pubmed.ncbi.nlm.nih.gov/3240710
https://pubmed.ncbi.nlm.nih.gov/3240710