Zobrazeno 1 - 10
of 71
pro vyhledávání: '"H. G. Mandel"'
Publikováno v:
Cancer Letters. 137:173-181
Ingestion of aflatoxin B1 is implicated in the high incidence of human liver cancers in several developing countries. An association has been detected between human exposure to aflatoxins, and mutations in the third base of codon 249 of the p53 gene
Publikováno v:
Carcinogenesis. 18:905-910
Activation of ras proto-oncogenes occurs frequently in vivo in chemically induced rodent tumours, including rat hepatomas induced by aflatoxin B 1 . This study examines the in vitro activation of a human ras gene by this mycotoxin. A plasmid containi
Publikováno v:
Carcinogenesis. 13:1853-1857
The hepatocarcinogenic responses of rats to aflatoxin B1 (AFB1) are believed to depend on microsomal activation of the toxin, followed by macromolecular binding. Dietary protein insufficiency is reported to reduce the level of microsomal metabolism,
Autor:
H G, Mandel
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 72(10)
To assess the status of basic science departments in academic health centers through a survey of department chairs.In November 1995 the National Caucus of Basic Biomedical Science Chairs developed a 35-item questionnaire that was sent to the presiden
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 66(2)
Autor:
H. G. Mandel
Publikováno v:
Journal of Clinical Investigation. 114:1687-1687
Publikováno v:
Biochemical Pharmacology. 31:2505-2511
The inhibition of protein synthesis by 8-azaguanine (azaG) in L1210 cells in culture was investigated. AzaG selectively inhibited protein synthesis at concentrations where viability was decreased significantly. AzaG altered the polyribosome sedimenta
Autor:
M. L. Seligman, H. G. Mandel
Publikováno v:
Journal of General Microbiology. 68:135-148
Summary: The addition of 0.4 mM-quinacrine to exponential cultures of Bacillus cereus led to the complete inhibition of growth, measured turbidimetrically. Certain metal ions such as Ca2+ and Mg2+ were partially effective in preventing growth inhibit
Autor:
H. G. Mandel, R. Tomchick
Publikováno v:
Journal of General Microbiology. 36:225-236
SUMMARY: Growth of Escherichia coli was partially inhibited by 1.2 x 10-4 m-ethidium bromide, a phenanthridinium trypanocide. In the presence of manganese the drug's effect was decreased. During growth in the presence of ethidium, RNA and protein con