Zobrazeno 1 - 10
of 28
pro vyhledávání: '"H. G. Archie Bouwer"'
Publikováno v:
Journal of Neuroimmunology. 278:194-199
Animals that have recovered from adoptively transferred EAE develop clinical disease signs 2-3days earlier than controls when challenged with encephalitogen. This may be due to the reactivation of donor-derived memory cells or stimulation of recipien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f58cf90b55fb5d32b1ec1f2b6b69c8c
https://doi.org/10.1016/j.jneuroim.2014.11.006
https://doi.org/10.1016/j.jneuroim.2014.11.006
Publikováno v:
Journal of Neuroimmunology. 274:46-52
We have used a peptide derived from Acanthamoeba castellanii (ACA) to treat the relapsing phase of EAE that develops in SJL mice following immunization with the PLP 139-151 peptide. The native sequence of the ACA 81-95 peptide that shares key residue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb5e7552fb2f9b62270ade4bddc74a2
https://doi.org/10.1016/j.jneuroim.2014.06.011
https://doi.org/10.1016/j.jneuroim.2014.06.011
Autor:
Dayana Rodriguez-Contreras, Scott M. Landfear, Elizabeth Kruvand, Xiuhong Feng, H. G. Archie Bouwer, Cosmo Buffalo, Stephen M. Beverley
Publikováno v:
Molecular Microbiology. 71:369-381
A glucose transporter null mutant of the parasitic protozoan Leishmania mexicana, in which three linked glucose transporter genes have been deleted by targeted gene replacement, is unable to replicate as amastigote forms within phagolysomes of mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abed3af7f84b9adbd902707ef71a25a
https://doi.org/10.1111/j.1365-2958.2008.06531.x
https://doi.org/10.1111/j.1365-2958.2008.06531.x
Publikováno v:
The Journal of Immunology. 180:3406-3416
The intracytosolic niche for replication of Listeria monocytogenes (Lm) facilitates delivery of bacteria-derived Ags into the MHC class I pathway for subsequent stimulation of CD8 effector T cells. Using Lm strains that are equivalent for in vivo vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ed8f4a9b89742c6b20debafe14c24a
https://doi.org/10.4049/jimmunol.180.5.3406
https://doi.org/10.4049/jimmunol.180.5.3406
Autor:
Timo Herrmann, Nicola Kimblin, Diana Ortiz, Steven Pierce, Scott M. Landfear, H. G. Archie Bouwer, Marco A. Sanchez
Publikováno v:
Molecular Microbiology. 64:1228-1243
Leishmania major and all other parasitic protozoa are unable to synthesize purines de novo and are therefore reliant upon uptake of preformed purines from their hosts via nucleobase and nucleoside transporters. L. major expresses two nucleobase perme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c5026f450e79d93bf93e630ace2163
https://doi.org/10.1111/j.1365-2958.2007.05730.x
https://doi.org/10.1111/j.1365-2958.2007.05730.x
Autor:
Y Gao, Anat A. Herskovits, Joanne Y.H. Lim, Adam Sampson-Johannes, David N. Cook, Martin A. Giedlin, John E. Hearst, Keith S. Bahjat, W Liu, William S. Luckett, D Kapadia, A Stassinopoulos, Pamela Schnupf, Thomas W. Dubensky, G Castro, H. G. Archie Bouwer, Dirk G. Brockstedt, M Leong, Daniel A. Portnoy
Publikováno v:
Nature Medicine. 11:853-860
We developed a new class of vaccines, based on killed but metabolically active (KBMA) bacteria, that simultaneously takes advantage of the potency of live vaccines and the safety of killed vaccines. We removed genes required for nucleotide excision r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b50e6b94dcb77d5fbcbc21970260631
https://doi.org/10.1038/nm1276
https://doi.org/10.1038/nm1276
Publikováno v:
The Journal of Immunology. 173:4084-4090
The immunologic requirements for generating long-lived protective CD8 T cell memory remain unclear. Memory CD8 populations generated in the absence of CD4 Th cells reportedly have functional defects, and at least a subset of CD8 T cells transiently e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4935ea4cf80da0fbd7d51d76e0f3b3e5
https://doi.org/10.4049/jimmunol.173.6.4084
https://doi.org/10.4049/jimmunol.173.6.4084
Publikováno v:
Proceedings of the National Academy of Sciences. 101:12318-12323
Previous studies have shown thatListeria monocytogenesflagellar motility genes, includingflaA, encoding flagellin, are transcriptionally down-regulated at 37°C. For someL. monocytogenesstrains, temperature-dependent motility gene expression is less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb10f5bc3b4922fe9cbbcd126cebab3
https://doi.org/10.1073/pnas.0404924101
https://doi.org/10.1073/pnas.0404924101
Autor:
Jeff F. Miller, Holly J. Starks, Ronald A. Barry, David J. Hinrichs, Darren E. Higgins, H. G. Archie Bouwer, Thomas W. Dubensky, Dirk G. Brockstedt, Martin A. Giedlin, Kevin W. Bruhn, Hao Shen
Publikováno v:
The Journal of Immunology. 173:420-427
The bacterium L. monocytogenes is a proposed vaccine carrier based upon the observation that this pathogen replicates within the intracytoplasmic environment facilitating delivery of Ag to the endogenous Ag processing and presentation pathway with su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461eec608f3fcac18bcbe36cb4dfaa87
https://doi.org/10.4049/jimmunol.173.1.420
https://doi.org/10.4049/jimmunol.173.1.420
Publikováno v:
Cellular Microbiology. 6:155-166
Summary The ActA protein of Listeria monocytogenes is a major virulence factor, essential for the recruitment and polymerization of host actin filaments that lead to intracellular motility and cell-to-cell spread of bacteria within the infected host.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0eddf054f25e1179902109a71b1edd6
https://doi.org/10.1046/j.1462-5822.2003.00348.x
https://doi.org/10.1046/j.1462-5822.2003.00348.x