Zobrazeno 1 - 10
of 77
pro vyhledávání: '"H. Fretz"'
Publikováno v:
ChemInform. 30
We have designed and synthesized a (3-aminomethyl-phenyl)-urea scaffold to mimic the X+1-Asn part of the minimal phosphopeptide sequence, Ac-pTyr-X+1-Asn-NH2, recognized by the Grb2-SH2 domain. The resulting compounds show the same degree of affinity
Publikováno v:
American Peptide Symposia ISBN: 0792351606
Intracellular signalling pathways that couple growth factor activation with cell control offer new target sites for pharmacological intervention in tumor therapy. This is the case for the growth factor receptor-bound protein 2 (Grb2), which links gro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::371c3b55f680f7ac7d6aa7cbc159af38
https://doi.org/10.1007/0-306-46862-x_240
https://doi.org/10.1007/0-306-46862-x_240
Publikováno v:
American Peptide Symposia ISBN: 0792351606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20bf7a4bf726e46d33ed2e49752c3e54
https://doi.org/10.1007/0-306-46862-x_309
https://doi.org/10.1007/0-306-46862-x_309
Publikováno v:
Journal of computer-aided molecular design. 15(5)
We have selected cyclin-dependent kinase 1 (CDK1), an enzyme participating in the regulation of the cell cycle, as a target in our efforts to discover new antitumor agents. By exploiting available structural information, we designed an ATP-site direc
Autor:
H. Rogg, H. Rüeger, S. Whitebread, M. Tintelnot-Blomley, L. Criscione, A. Schaffhauser, H. Fretz
Publikováno v:
Peptides 1994 ISBN: 9789072199218
Peptides 1994
Peptides 1994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e85d13dcf1a5f4dfdc8d0ed68c7c25c
https://doi.org/10.1007/978-94-011-1468-4_266
https://doi.org/10.1007/978-94-011-1468-4_266
Publikováno v:
Peptides 1992 ISBN: 9789401046466
Peptides 1992
Peptides 1992
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767fe0a2175f66d30d2c6d52635080f5
https://doi.org/10.1007/978-94-011-1470-7_7
https://doi.org/10.1007/978-94-011-1470-7_7
Akademický článek
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Publikováno v:
European Journal of Pharmaceutical Sciences. 2:137
Autor:
L. Criscione, M. Tintelnot-Blomley, E. Grouzmann, H. Fretz, H. Rüeger, S. Whitebread, H. Rogg
Publikováno v:
Neuropeptides. 26:13
Autor:
A H, Fretz
Publikováno v:
Science (New York, N.Y.). 87(2259)