Zobrazeno 1 - 10 of 78 pro vyhledávání: '"H. Fai Poon"'
2
Akademický článek
Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: Insights into the development of Alzheimer's disease
Autor: D. Allan Butterfield, H. Fai Poon, Daret St. Clair, Jeffery N. Keller, William M. Pierce, Jon B. Klein, William R. Markesbery
Publikováno v: Neurobiology of Disease, Vol 22, Iss 2, Pp 223-232 (2006)
Mild cognitive impairment (MCI) is generally referred to the transitional zone between normal cognitive function and early dementia or clinically probable Alzheimer's disease (AD). Oxidative stress plays a significant role in AD and is increased in t
Externí odkaz: https://doaj.org/article/342e87a756104355a1145783e660ef7e
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3
Akademický článek
Identification of nitrated proteins in Alzheimer's disease brain using a redox proteomics approach
Autor: Rukhsana Sultana, H. Fai Poon, Jian Cai, William M. Pierce, Michael Merchant, Jon B. Klein, William R. Markesbery, D. Allan Butterfield
Publikováno v: Neurobiology of Disease, Vol 22, Iss 1, Pp 76-87 (2006)
Nitric oxide (NO) has been implicated in the pathophysiology of a number of neurodegenerative diseases including Alzheimer's disease (AD). In the present study, using a proteomics approach, we identified enolase, glyceraldehyde-3-phosphate dehydrogen
Externí odkaz: https://doaj.org/article/18810c0f3ede42178373bfd509e8feae
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4
Akademický článek
Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease
Autor: H. Fai Poon, Mark Frasier, Nathan Shreve, Vittorio Calabrese, Benjamin Wolozin, D. Allan Butterfield
Publikováno v: Neurobiology of Disease, Vol 18, Iss 3, Pp 492-498 (2005)
Parkinson's disease (PD) is the most common neurodegenerative movement disorder and is characterized by the loss of dopaminergic neurons in the substantia nigra compacta. α-Synuclein is strongly implicated in the pathophysiology of PD because aggreg
Externí odkaz: https://doaj.org/article/f2267929dbc44b1297b692ce78da5293
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6
Soy hydrolysate mimic autocrine growth factors effect of conditioned media to promote single CHO-K1 cell proliferation
Autor: Xu Wenyan, Sasi Bhushan, Yu Xiaoyu, Jiewei Zhang, Siddalinga Prasad, Yuan Jun, Wu Fan, H. Fai Poon, Kamal Prasad
Publikováno v: Tissue and Cell. 58:130-133
The increasingly competitive biopharmaceutical industry requires companies to focus on rapid and low-cost cell line development. Single-cell cloning (SCC) is a critical and high-value process for cell line development, and typically problematic becau
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc49b830e7173c81b97418ee1ce4944
https://doi.org/10.1016/j.tice.2019.05.005
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7
Chemometric identification of canonical metabolites linking critical process parameters to monoclonal antibody production during bioprocess development
Autor: H. Fai Poon, Haibin Wang, Lei Nie, Xu Yan, Lijuan Shen, Haibin Qu, Wenyan Xu, Shiwei Miao
Publikováno v: Chinese Journal of Chemical Engineering. 27:1171-1176
A deeper understanding of the biological events occurring when bioprocess parameters changed will be of great value in improving the monoclonal antibodies (mAbs) production. Design of experiment (DoE) was applied to investigate the effect of process
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d832d4dcb8009d1c94bfc9601dc81c2
https://doi.org/10.1016/j.cjche.2018.10.009
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9
The Scattered Twelve Tribes of HEK293
Autor: Wayne W. Xu, Snake Jiang, H. Fai Poon, Henry Yu, Jun Yuan
Publikováno v: Biomedical and Pharmacology Journal. 11:621-623
Their ease of growth and transfection makes HEK293 cells a common cell culture in academic research. In addition, high transfection efficiency of HEK293 cells enable production of exogenous proteins or viruses for pharmaceutical and biomedical resear
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31a0da0a85b4956e0212e43df04126e2
https://doi.org/10.13005/bpj/1414
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