Zobrazeno 1 - 10
of 52
pro vyhledávání: '"H. F. Hoff"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 7, Pp 1347-1360 (1997)
Accumulation of the insoluble lipid-protein complex, ceroid, is a characteristic of atherosclerotic plaques. To determine whether deficient processing of cholesteryl esters in oxidized (ox) low density lipoprotein (LDL) contributes to ceroid formatio
Externí odkaz:
https://doaj.org/article/ae0645a42fb449e9a93af78c3e1a81cd
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 11, Pp 1124-1134 (1990)
A lipoprotein particle designated A-LDL, which contains apolipoprotein B (apoB) and which is the size of plasma low density lipoproteins (LDL), was isolated from homogenates of human aortic athersclerotic plaques by a combination of affinity chromato
Externí odkaz:
https://doaj.org/article/7a5685d59f984d89a82eb7f0e5c352f6
Autor:
R K Randolph, H F Hoff
Publikováno v:
Journal of Lipid Research, Vol 27, Iss 3, Pp 307-315 (1987)
Exchange and net mass efflux of cholesterol were investigated in [3H]cholesterol-labeled or cholesteryl ester-loaded murine peritoneal macrophages, respectively. Macrophages were subjected to mild proteolysis prior to measurements of mass efflux or e
Externí odkaz:
https://doaj.org/article/e49d21dec0524fa793abf39d27a85fbb
Autor:
J. A. O'Neil, H. F. Hoff
Publikováno v:
Klinische Wochenschrift. 69:1032-1038
Oxidation of LDL is proposed to accelerate atherogenesis by the following sequence of events. LDL accumulates in atherosclerotic plaques, presumably due to interaction with intimal proteoglycans. The LDL then undergoes oxidation, and aldehydic produc
Publikováno v:
Cellular and molecular life sciences : CMLS. 61(13)
Lipid peroxidation has been implicated in many age-associated disorders including macular degeneration of the retina. We sought to elucidate the mechanism by which accumulation of oxidized LDL (oxLDL) reduces the ability of retinal pigment epithelium
Publikováno v:
Investigative ophthalmologyvisual science. 42(11)
To examine the effects of oxidized low-density lipoproteins (oxLDL) on phagocytosis and processing of photoreceptor outer segments (OS) by retinal pigment epithelial (RPE) cells.Confluent cultures of RPE-J cells were pretreated with oxLDL or LDL, and
Publikováno v:
Journal of lipid research. 41(9)
Oxidation of low density lipoproteins (LDL) induced by incubation with Cu(2+) ions results in the formation of a heterogeneous group of aldehydic adducts on lysyl residues (Lys) of apolipoprotein B (apoB) that are thought to be responsible for the up
Autor:
G B, Smejkal, H F, Hoff
Publikováno v:
BioTechniques. 16(1)
Autor:
G B, Smejkal, H F, Hoff
Publikováno v:
BioTechniques. 15(5)
Publikováno v:
Journal of lipid research. 34(11)
Aggregation is a characteristic of extensively oxidized (ox-) LDL. We wished to determine whether this structural change contributed even more to the documented poor degradation in macrophages of ox-LDL than the chemical changes. When protein degrada