Zobrazeno 1 - 10
of 12
pro vyhledávání: '"H. F. Bakkeren"'
Autor:
H. C. P. F. Roelen, J. H. Van Boom, Martin K. Bijsterbosch, H. J. M. Kempen, T. J. C. Van Berkel, H. F. Bakkeren
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 12:1153-1160
We described earlier the effect of tris-gal-chol (a triantennary galactose structure coupled to cholesterol) on the fate of low density lipoprotein (LDL) and high density lipoprotein (HDL). Tris-gal-chol-loaded LDL and HDL are both efficiently cleare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15448cdfc7a3b0dfbdf190a560bb69d3
https://doi.org/10.1161/01.atv.12.10.1153
https://doi.org/10.1161/01.atv.12.10.1153
Autor:
Antonio M. Gotto, T. J. C. Van Berkel, H. F. Bakkeren, Martin K. Bijsterbosch, L. C. Smith, F. Bernini
Publikováno v:
Arteriosclerosis and Thrombosis: A Journal of Vascular Biology. 11:1806-1813
Reduction of the blood levels of low density lipoprotein (LDL) is important for lowering the incidence of atherosclerosis. In this study, LDL was directed to rat parenchymal liver cells by lactosaminated Fab fragments of anti-apolipoprotein B antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bda769428bd5b3ef5529b24a8b31c53
https://doi.org/10.1161/01.atv.11.6.1806
https://doi.org/10.1161/01.atv.11.6.1806
Autor:
H.J.M. Kempen, H. C. P. F. Roelen, H. F. Bakkeren, J. H. Van Boom, T. J. C. Van Berkel, G. A. Van Der Marel, M. Buytenhek, Martin K. Bijsterbosch
Publikováno v:
Journal of Medicinal Chemistry. 34:1036-1042
The synthesis of several monogalactoside-terminated phosphorothiolated cholesteryl derivatives is described. Monogalactosyl derivatives are coupled by phosphorothiolation to cholesterol by using ethylene glycol units as hydrophilic spacer moieties. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a771dbfc09e80ffe7b551357bd6d0cc
https://doi.org/10.1021/jm00107a024
https://doi.org/10.1021/jm00107a024
Publikováno v:
Biochemical Journal. 268:685-691
Acetylated low-density lipoprotein (acetyl-LDL), biologically labelled in the cholesterol moiety of cholesteryl oleate, was injected into control and oestrogen-treated rats. The serum clearance, the distribution among the various lipoproteins, the he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5f8cd6a9993d36b2dfb5986c82c489
https://doi.org/10.1042/bj2680685
https://doi.org/10.1042/bj2680685
Publikováno v:
The Biochemical journal. 299
Previous in vivo studies have demonstrated that small galactose-exposing particles are preferentially internalized by the asialoglycoprotein receptor on the parenchymal liver cell and large particles by the galactose-particle receptor on the Kupffer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9277495a5406dc151bbc70da3a127d35
https://pubmed.ncbi.nlm.nih.gov/8166653
https://pubmed.ncbi.nlm.nih.gov/8166653
Publikováno v:
The Biochemical journal. 299
The characteristics of the recognition system involved in the binding of galactose-exposing particles to freshly isolated rat Kupffer cells were determined. For this purpose we used iodinated lactosylated low-density lipoprotein (125I-Lac-LDL) as a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a0178363171608d2a8e99e040988a9
https://pubmed.ncbi.nlm.nih.gov/8166651
https://pubmed.ncbi.nlm.nih.gov/8166651
Autor:
D. Schouten, B Esbach, T. J. C. Van Berkel, Dick Knook, Adriaan Brouwer, H. F. Bakkeren, M N Pieters
Publikováno v:
The Biochemical journal. 280
[3H]Cholesteryl ester-labelled human high-density lipoprotein (HDL) was injected into rats and its decay, intrahepatic cellular distribution and the kinetics of biliary secretion were determined. At 10 min after injection the hepatic uptake of choles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60ae0ca185a85f9e23eb8d4a887281b
https://pubmed.ncbi.nlm.nih.gov/1747108
https://pubmed.ncbi.nlm.nih.gov/1747108
Autor:
M F, Kleinherenbrink-Stins, J, van der Boom, H F, Bakkeren, P J, Roholl, A, Brouwer, T J, van Berkel, D L, Knook
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 63(1)
The in vivo interaction of low density lipoproteins (LDL) with the liver was investigated by visualizing the endocytic route using light- and immunoelectron microscopic methods in control and 17 alpha-ethinyl estradiol (EE)-treated rats. The fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bef3dafd673c167d691c4091ccb6afb
https://pubmed.ncbi.nlm.nih.gov/2374402
https://pubmed.ncbi.nlm.nih.gov/2374402
Publikováno v:
Journal of Biological Chemistry. 261:8908-8913
Human low density lipoprotein (LDL), radiolabeled in the cholesteryl ester moiety, was injected into estrogen-treated and -untreated rats. The hepatic and extrahepatic distribution and biliary secretion of [3H]cholesteryl esters were determined at va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7184f6bb4839307a0a856b2498647fc8
https://doi.org/10.1016/s0021-9258(19)84468-x
https://doi.org/10.1016/s0021-9258(19)84468-x
Autor:
Roel J. Vonk, Rick Havinga, T. J. C. Van Berkel, J F Nagelkerke, Folkert Kuipers, H. F. Bakkeren
Publikováno v:
Biochemical Journal, 257(3), 699-704. PORTLAND PRESS LTD
Biliary secretion of the cholesteryl ester moiety of (modified) low-density lipoprotein (LDL) was examined under various experimental conditions in the rat. Human LDL or acetylated LDL (acetyl-LDL), radiolabelled with [3H]cholesteryl oleate, was admi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2482a411996ec0a1c8d934f3975a0a0e
https://doi.org/10.1042/bj2570699
https://doi.org/10.1042/bj2570699