Zobrazeno 1 - 10
of 117
pro vyhledávání: '"H. Erasmus"'
Autor:
Shanna S. Leventhal, Thomas Bisom, Dean Clift, Deepashri Rao, Kimberly Meade-White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy Hinkley, Steven J. Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, Heinz Feldmann, David W. Hawman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a negative-sense RNA virus spread by Hyalomma genus ticks across Europe, Asia, and Africa. CCHF disease begins as a non-specific febrile illness which may progress into a severe hemorrhagic di
Externí odkaz:
https://doaj.org/article/a6d956186c9942bda98b2bc1f3d16cfd
Autor:
Kristina R. Edwards, Harman Malhi, Karina Schmidt, Amelia R. Davis, Leah J. Homad, Nikole L. Warner, Crystal B. Chhan, Samuel C. Scharffenberger, Karen Gaffney, Troy Hinkley, Nicole B. Potchen, Jing Yang Wang, Jason Price, M. Juliana McElrath, James Olson, Neil P. King, Jennifer M. Lund, Zoe Moodie, Jesse H. Erasmus, Andrew T. McGuire
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Epstein-Barr virus (EBV) is associated with several malignancies, neurodegenerative disorders and is the causative agent of infectious mononucleosis. A vaccine that prevents EBV-driven morbidity and mortality remains an unmet need. EBV is or
Externí odkaz:
https://doaj.org/article/fab2a8de7ed045b19c19552e4e00f12e
Autor:
Zachary MacMillen, Kiara Hatzakis, Adrian Simpson, Melanie J. Shears, Felicia Watson, Jesse H. Erasmus, Amit P. Khandhar, Brandon Wilder, Sean C. Murphy, Steven G. Reed, James W. Davie, Marion Avril
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-15 (2024)
Abstract Malaria, caused by Plasmodium parasites, remains one of the most devastating infectious diseases worldwide, despite control efforts to lower morbidity and mortality. Both advanced candidate vaccines, RTS,S and R21, are subunit (SU) vaccines
Externí odkaz:
https://doaj.org/article/9795eb7e6c784cf78f5439f20cf26fbb
Autor:
Jean Mukherjee, Celinia A. Ondeck, Jacqueline M. Tremblay, Jacob Archer, Michelle Debatis, Alexa Foss, Junya Awata, Jesse H. Erasmus, Patrick M. McNutt, Charles B. Shoemaker
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Single domain antibodies (sdAbs), also called nanobodies, have substantial biophysical advantages over conventional antibodies and are increasingly being employed as components of immunotherapeutic agents. One particularly favorable property
Externí odkaz:
https://doaj.org/article/fbf6a19e8929440a86eeb6f344288f44
Autor:
Megan A O'Connor, David W Hawman, Kimberly Meade-White, Shanna Leventhal, Wenjun Song, Samantha Randall, Jacob Archer, Thomas B Lewis, Brieann Brown, Megan N Fredericks, Kaitlin R Sprouse, Hillary C Tunggal, Mara Maughan, Naoto Iwayama, Chul Ahrens, William Garrison, Solomon Wangari, Kathryn A Guerriero, Patrick Hanley, Jamie Lovaglio, Greg Saturday, David Veesler, Paul T Edlefsen, Amit P Khandhar, Heinz Feldmann, Deborah Heydenburg Fuller, Jesse H Erasmus
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011298 (2023)
The global SARS-CoV-2 pandemic prompted rapid development of COVID-19 vaccines. Although several vaccines have received emergency approval through various public health agencies, the SARS-CoV-2 pandemic continues. Emergent variants of concern, waning
Externí odkaz:
https://doaj.org/article/d4af23eb43be40bcaa467db922cd5121
Autor:
David W. Hawman, Kimberly Meade-White, Chad Clancy, Jacob Archer, Troy Hinkley, Shanna S. Leventhal, Deepashri Rao, Allie Stamper, Matthew Lewis, Rebecca Rosenke, Kyle Krieger, Samantha Randall, Amit P. Khandhar, Linhue Hao, Tien-Ying Hsiang, Alexander L. Greninger, Michael Gale, Jr, Peter Berglund, Deborah Heydenburg Fuller, Kyle Rosenke, Heinz Feldmann, Jesse H. Erasmus
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104196- (2022)
Summary: Background: In late 2021, the SARS-CoV-2 Omicron (B.1.1.529) variant of concern (VoC) was reported with many mutations in the viral spike protein that were predicted to enhance transmissibility and allow viral escape of neutralizing antibodi
Externí odkaz:
https://doaj.org/article/ab324282f355407caf9cfe9a89fda64c
Autor:
Shanna S. Leventhal, Kimberly Meade-White, Deepashri Rao, Elaine Haddock, Jacqueline Leung, Dana Scott, Jacob Archer, Samantha Randall, Jesse H. Erasmus, Heinz Feldmann, David W. Hawman
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104188- (2022)
Summary: Background: Crimean-Congo hemorrhagic fever virus is the cause of a severe hemorrhagic fever with cases reported throughout a wide-geographic region. Spread by the bite of infected ticks, contact with infected livestock or in the health care
Externí odkaz:
https://doaj.org/article/2faa9f27af3c480298ba8bdae9797f88
Autor:
Krisangel López, Sarah N. Wilson, Sheryl Coutermash-Ott, Manette Tanelus, William B. Stone, Danielle L. Porier, Dawn I. Auguste, John A. Muller, Orchid M. Allicock, Sally L. Paulson, Jesse H. Erasmus, Albert J. Auguste
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 1649-1659 (2021)
Cache Valley virus (CVV) is a prevalent emerging pathogen of significant importance to agricultural and human health in North America. Emergence in livestock can result in substantial agroeconomic losses resulting from the severe embryonic lethality
Externí odkaz:
https://doaj.org/article/68f3e42532554a6b9d16fcf4c0e39ffc
Autor:
Alexandra C Willcox, Kevin Sung, Meghan E Garrett, Jared G Galloway, Jesse H Erasmus, Jennifer K Logue, David W Hawman, Helen Y Chu, Kim J Hasenkrug, Deborah H Fuller, Frederick A Matsen Iv, Julie Overbaugh
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010155 (2022)
Macaques are a commonly used model for studying immunity to human viruses, including for studies of SARS-CoV-2 infection and vaccination. However, it is unknown whether macaque antibody responses resemble the response in humans. To answer this questi
Externí odkaz:
https://doaj.org/article/d06c3815d7874833bff7c9995c4d3884
Autor:
Jesse H. Erasmus, Jacob Archer, Jasmine Fuerte-Stone, Amit P. Khandhar, Emily Voigt, Brian Granger, Robin G. Bombardi, Jennifer Govero, Qing Tan, Lorellin A. Durnell, Rhea N. Coler, Michael S. Diamond, James E. Crowe, Jr., Steven G. Reed, Larissa B. Thackray, Robert H. Carnahan, Neal Van Hoeven
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 402-414 (2020)
Monoclonal antibody (mAb) therapeutics are an effective modality for the treatment of infectious, autoimmune, and cancer-related diseases. However, the discovery, development, and manufacturing processes are complex, resource-consuming activities tha
Externí odkaz:
https://doaj.org/article/caf03de341314d739fa7688cad7cbd42