Zobrazeno 1 - 10
of 45
pro vyhledávání: '"H. E. Shannon"'
Publikováno v:
Computational and Mathematical Methods in Medicine, Vol 8, Iss 4, Pp 225-234 (2007)
Using wavelet analysis we have detected the presence of chirps in seizure EEG signals recorded from kindled epileptic rats. Seizures were induced by electrical stimulation of the amygdala and the EEG signals recorded from the amygdala were analyzed u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b14334d7a3c62ba16ddcf24cf801826c
https://doi.org/10.1080/17486700701528970
https://doi.org/10.1080/17486700701528970
Publikováno v:
Behavioural Pharmacology. 12:613-620
The ability of m-CPP [1-(m-chlorophenyl)piperazine] to produce hypolocomotion is well documented. This effect has been postulated to be due to activation of the 5-HT(2C) receptor. It is only recently that the tools necessary to clearly delineate whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48230b1843ae8ddc7192ee0a019a3ce
https://doi.org/10.1097/00008877-200112000-00005
https://doi.org/10.1097/00008877-200112000-00005
Autor:
C K, Jones, H E, Shannon
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 294(3)
The purpose of the present study was to determine the effects of muscarinic cholinergic receptor antagonists and agonists on prepulse inhibition (PPI) of the acoustic startle reflex in rats. The muscarinic receptor antagonist scopolamine (0.03-1.0 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f879f7d8d0c858c35eda03fba02337d
https://pubmed.ncbi.nlm.nih.gov/10945854
https://pubmed.ncbi.nlm.nih.gov/10945854
Autor:
H E Shannon, E A Lutz
Publikováno v:
Psychopharmacology. 149(1)
Rationale: Previous studies have suggested that the α2-adrenergic receptor antagonist yohimbine produced antinociceptive effects in the formalin test in rats. However, yohimbine is also an agonist at serotonin (5-HT)1A receptors, suggesting the poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfb5f31ab4ca1347e8ca19070c9a144
https://pubmed.ncbi.nlm.nih.gov/10789888
https://pubmed.ncbi.nlm.nih.gov/10789888
Autor:
M J, Sheardown, H E, Shannon, M D, Swedberg, P D, Suzdak, F P, Bymaster, P H, Olesen, C H, Mitch, J S, Ward, P, Sauerberg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(2)
The analgesic effects of a series of muscarinic agonists were investigated by use of the mouse acetic acid writhing, grid-shock, hot-plate and tail-flick tests. The compounds tested were oxotremorine, pilocarpine, arecoline, aceclidine, RS86 and four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::79ecf1e43cfe545617ce8048e2834e84
https://pubmed.ncbi.nlm.nih.gov/9152396
https://pubmed.ncbi.nlm.nih.gov/9152396
Autor:
M D, Swedberg, M J, Sheardown, P, Sauerberg, P H, Olesen, P D, Suzdak, K T, Hansen, F P, Bymaster, J S, Ward, C H, Mitch, D O, Calligaro, N W, Delapp, H E, Shannon
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(2)
Butylthio[2.2.2] ((+)-(S)-3-(4-(Butylthio)-1,2,5-thiadiazol-3-yl)-1-azabicyclo[2.2. 2] octane) is an agonist/antagonist at muscarinic receptors. The analgesic potential of butylthio[2.2.2] was assessed in the mouse by use of the grid-shock, tail-flic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f53abf6a2ac73b4b6897589c371673a
https://pubmed.ncbi.nlm.nih.gov/9152397
https://pubmed.ncbi.nlm.nih.gov/9152397
Autor:
H E, Shannon, M J, Sheardown, F P, Bymaster, D O, Calligaro, N W, Delapp, J, Gidda, C H, Mitch, B D, Sawyer, P W, Stengel, J S, Ward, D T, Wong, P H, Olesen, P D, Suzdak, P, Sauerberg, M D, Swedberg
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 281(2)
Butylthio[2.2.2], ((+)-(S)-3-(4-butylthio-1,2,5-thiadiazol-3-yl)-1-azabicyclo[2.2.2] octane; LY297802/NNC11-1053) is a muscarinic receptor ligand which is equiefficacious to morphine in producing antinociception. In vitro, butylthio[2.2.2] had high a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::60ea834b475d911247439bbb12b0e68f
https://pubmed.ncbi.nlm.nih.gov/9152398
https://pubmed.ncbi.nlm.nih.gov/9152398
Publikováno v:
Alzheimer disease and associated disorders. 11
The therapeutic effects of selective cholinergic replacement using oral xanomeline, an m1/m4 receptor agonist, were assessed in a multicenter study of 343 patients with Alzheimer disease (AD). Patients were randomized to parallel treatment arms (plac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c56df22bb865cdcca8823119b9e0b5a6
https://pubmed.ncbi.nlm.nih.gov/9339268
https://pubmed.ncbi.nlm.nih.gov/9339268
Autor:
L, Farde, T, Suhara, C, Halldin, H, Nybäck, Y, Nakashima, C G, Swahn, P, Karlsson, N, Ginovart, F P, Bymaster, H E, Shannon, C, Foged, P D, Suzdak, P, Sauerberg
Publikováno v:
Dementia (Basel, Switzerland). 7(4)
Xanomeline, a substituted TZTP, is a new M1 selective muscarinic agonist in clinical trials for Alzheimer's disease. The brain uptake of [11C]xanomeline and the analog [11C]butylthio-TZTP was examined by positron emission tomography (PET). Radioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac54b9cd670e6fe91d63e52f9bf28896
https://pubmed.ncbi.nlm.nih.gov/8835881
https://pubmed.ncbi.nlm.nih.gov/8835881
Publikováno v:
The Journal of urology. 155(1)
To evaluate functional characteristics of regenerated bladder induced by small intestinal submucosa (SIS).Strips from bladder regenerated from SIS and normal rat bladder were evaluated by in vitro muscle bath contractility studies.The present results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::88ff38e2304a40e276bbfabb5c031874
https://pubmed.ncbi.nlm.nih.gov/7490890
https://pubmed.ncbi.nlm.nih.gov/7490890