Zobrazeno 1 - 10
of 11
pro vyhledávání: '"H. E. Scribner"'
Publikováno v:
Toxicological Sciences. 46:324-332
Autor:
K. V. Maher, R. H. Larkin, E. D. Weiler, K. H. Reinert, H. M. Ellis, W. T. Lynch, C. B. Frederick, S. D. Boyce, Michael A. Jayjock, H. E. Scribner
Publikováno v:
American Industrial Hygiene Association Journal. 58:814-819
The object of this effort was to organize and manage product risk assessment as a consistent and scientifically based process in which the specific elements, the relationship with clients, and the boundaries of the procedure were analyzed and defined
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 46(2)
To develop a better understanding of the relationship between ethyl acrylate (EA)-induced cytotoxicity and mutation frequency in the mouse lymphoma assay (MLA) we measured the effects of EA treatment to ML cells on: (1) nonprotein sulfhydryl (NPS) le
Autor:
H E, Scribner, E D, Weiler
Publikováno v:
Quality assurance (San Diego, Calif.). 4(3)
Quality improvement initiatives for a corporate toxicology group require a high level of managerial commitment to a bring about lasting change, a well-enunciated plan, professional training, effective communication, and reward and accountability syst
Publikováno v:
Quality assurance (San Diego, Calif.). 1(4)
One cannot manage a health or environmental risk of unknown dimension. Thus, the rational and cost-effective control of any risk lies first in its reasoned assessment. The assessment of risk is a scientific endeavor which embodies the intellectual us
Publikováno v:
Toxicological Sciences. 8:549-561
Publikováno v:
Journal of Applied Toxicology. 4:66-74
Genetic Toxicology Association members from governmental, contract and industrial laboratories were surveyed to determine the status of 28 recognized genetic toxicology assays in their laboratories. Compiled results of the 1982 questionnaire indicate
Publikováno v:
Journal of Toxicology and Environmental Health. 22:63-78
The in vivo-in vitro DNA repair and DNA replication assay in mouse hepatocytes has promise as a short-term test for detecting potential mouse liver carcinogens. In addition, this assay may provide information on the mode of action of known hepatic ca
Publikováno v:
Fundamental and Applied Toxicology. 8:549-561
Following oral dosing of [2,3-14C]acrylic acid (AA; 4, 40, or 400 mg/kg) and [2,3-14C]ethyl acrylate (EA; 2, 20, or 200 mg/kg), the dosed radioactivity was rapidly excreted, with 50-75% of the dose for both compounds eliminated within 24 hr. The prim
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 8(4)
Following oral dosing of [2,3-14C]acrylic acid (AA; 4, 40, or 400 mg/kg) and [2,3-14C]ethyl acrylate (EA; 2, 20, or 200 mg/kg), the dosed radioactivity was rapidly excreted, with 50-75% of the dose for both compounds eliminated within 24 hr. The prim