Zobrazeno 1 - 10
of 188
pro vyhledávání: '"H. E. Hudson"'
Autor:
Mria Chowdhury, Robert H. E. Hudson
Publikováno v:
Chemical record (New York, N.Y.).
Over the past two decades, it has become abundantly clear that nucleic acid biochemistry, especially with respect to RNA, is more convoluted and complex than previously appreciated. Indeed, the application and exploitation of nucleic acids beyond the
Publikováno v:
Molecules, Vol 25, Iss 8, p 1995 (2020)
There has been much effort to exploit fluorescence techniques in the detection of nucleic acids. Canonical nucleic acids are essentially nonfluorescent; however, the modification of the nucleobase has proved to be a fruitful way to engender fluoresce
Externí odkaz:
https://doaj.org/article/fca7fc78b261431c8b13ecf7ba680c91
Publikováno v:
BiopolymersREFERENCES. 113(1)
Peptide nucleic acid (PNA) is a mimic of nucleic acids that is able to bind complementary oligonucleotides with high affinity and excellent selectivity. As such, the use of PNA has been proposed in numerous applications in biochemistry, medicine, and
Autor:
Alexandra Joubert, Pauline Lejault, Anton Granzhan, Julien Boudon, Jean-Baptiste Boulé, Jeremie Mitteaux, Filip Wojciechowski, Robert H. E. Hudson, Claude P. Gros, David Monchaud, Nicolas Desbois
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
Journal of the American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
Journal of the American Chemical Society, 2021, 143 (32), pp.12567-12577. ⟨10.1021/jacs.1c04426⟩
International audience; The quest for small molecules that strongly bind to Gquadruplex-DNA (G4), so-called G4 ligands, has invigorated the G4 research field from its very inception. Massive efforts have been invested to discover or rationally design
Publikováno v:
Microporous and Mesoporous Materials. 284:366-377
Magnetic MCM-41 nanoparticles were synthesized via Fe3O4-doped into mesoporous channels of MCM-41 nanoparticles and further, a new organometallic complex of palladium was supported on its inner surface (Pd-imi@MCM-41/Fe3O4). This immobilized catalyst
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 5, Pp o556-o557 (2014)
In the title compound, C18H23N5O4·CH2Cl2, the dichloromethane solvent molecule is disordered over two sets of sites in a 0.630 (13):0.370 (13) ratio. The dihedral angle between the uracil and phenyl rings is 30.2 (1)°. In the crystal, the principal
Externí odkaz:
https://doaj.org/article/d7ff8bd95a464bf0b97f82fca55a17b2
Publikováno v:
Canadian Journal of Chemistry. 96:1093-1100
Three new fluorescent 7-deaza-2′-deoxyadenosine analogs were synthesized via the Sonogashira cross-coupling reaction of 7-iodo-7-deaza-2′-deoxyadenosine with 1-ethynylpyrene, 2-ethynyl-6-methoxynaphthalene, and 9-ethynylphenanthrene. The spectral
Publikováno v:
Catalysis Letters. 149:228-247
A new acidic mesoporous catalyst (FSM-16/AEPC-SO3H) was successfully synthesized and characterized by FT-IR, TGA, XRD, SEM, TEM, EDS and BET techniques. The FSM-16/AEPC-SO3H showed excellent catalytic activity for the synthesis of 1,8-dioxo-octahydro
Autor:
Alexandra Joubert, Nicolas Desbois, Pauline Lejault, Jean-Baptiste Boulé, Anton Granzhan, Filip Wojciechowski, David Monchaud, Robert H. E. Hudson, Marc Pirrotta, Jeremie Mitteaux, Claude P. Gros
The quest for small molecules that avidly bind to G-quadruplex-DNA (G4-DNA, or G4), so called G4-ligands, has invigorated the G4 research field from its very inception. Massive efforts have been invested to i- screen or design G4-ligands, ii- evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ae530f5ce376ec2f2de1798406f8df
https://doi.org/10.1101/2020.11.16.382176
https://doi.org/10.1101/2020.11.16.382176
Autor:
Sreenivas Kanugula, Melanie S. Rogers, Delshanee Kotandeniya, Natalia Y. Tretyakova, Jenna Fernandez, Robert H. E. Hudson, Freddys Rodriguez, John D. Lipscomb
Publikováno v:
Biopolymers
Cellular exposure to tobacco-specific nitrosamines causes formation of promutagenic O(6)-[4-oxo-4-(3-pyridyl)but-1-yl]guanine (O(6)-POB-G) and O(6)-methylguanine (O(6)-Me-G) adducts in DNA. These adducts can be directly repaired by O(6)-alkylguanine-