Zobrazeno 1 - 10 of 45 pro vyhledávání: '"H. E. Howard-Lock"'
1
Structures of Gold(I) and Silver(I) Thiolate Complexes of Medicinal Interest: A Review and Recent Results
Autor: H. E. Howard-Lock
Publikováno v: Metal-Based Drugs
We review the crystal structures, electrospray ionization mass spectra (ESI-MS) data and chiral HPLC data for the racemic and optically pure mononuclear AuL2 complexes, and for racemic [AuLI]n and optically pure [AgLII]n polymers (LI = thiomalate, LI
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22e85c8fe63ab0290ac9c1c8dcba672
http://europepmc.org/articles/PMC2365178
Zobrazit plný text záznamu
2
N10-(2′-Mercaptoethanoyl)-2,2,5,5-tetramethyl-3,4-diathia-7,10-diaza-bicyclo[5.3.0]decane and its reaction with oxotrichlorobis(triphenylphosphine)rhenium(V)
Autor: H. E. Howard-Lock, Colin J. L. Lock, Russell A. Bell, H. Alarabi, J. Kowanetz
Publikováno v: Canadian Journal of Chemistry. 74:574-582
The ligand molecule N10-(2′-mercaptoethanoyl)-2,2,5,5-tetramethyl-3,4-dithia-7,10-diazabicyclo[5.3.0]decane has been prepared and characterized by 1H and 13C NMR spectroscopy and by mass spectrometry. The protected analogue, N10-[(2′-triphenylmet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9aa2c023d1fc835e0e372bd4ffead8d4
https://doi.org/10.1139/v96-061
Zobrazit plný text záznamu
4
The interaction of D-penicillamine with aldehydes and ketones: 2-phenyl-5,5-dimethylthiazolidine-4-carboxylic acid
Autor: Colin J. L. Lock, M. Schmidt, James F. Britten, H. E. Howard-Lock, Russell A. Bell
Publikováno v: Canadian Journal of Chemistry. 72:1621-1624
The reaction of D-penicillamine and benzaldehyde yielded 2-phenyl-5,5-dimethylthiazolidine-4-carboxylic acid. The structure was determined by single crystal X-ray diffraction. Crystals were monoclinic, P21, a = 9.785(2), b = 6.941(1), c = 10.399(2)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68ff0d46f890c3eed775e85954b61de1
https://doi.org/10.1139/v94-203
Zobrazit plný text záznamu
6
Amino acid/zwitterion equilibria II: vibrational and NMR studies of substituted thiazolidine-4-carboxylic acids
Autor: H. E. Howard-Lock, Colin J. L. Lock, M. L. Martins
Publikováno v: Canadian Journal of Chemistry. 69:1721-1727
Infrared and Raman spectra (4000–100 cm) of solid samples of seven different 2-phenyl-, N-benzoyl-, and 2-ethyl-2 methyl derivatives of L-cysteine and D-penicillamine have been observed and assigned. Proton and 13C nuclear magnetic resonance spectr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab402e3c581ccc048bc9d5623c1d8013
https://doi.org/10.1139/v91-252
Zobrazit plný text záznamu
7
Gold complex research in medical science. Difficulties with experimental design
Autor: Colin J. L. Lock, Walter F. Kean, H. E. Howard-Lock
Publikováno v: Inflammopharmacology. 1:103-114
Despite the use of gold complexes in modern medicine for over 100 years and the use of gold complexes in the management of rheumatoid disease for more than 60 years, the definitive mechanisms of action for efficacy and for toxicity have not been esta
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::673005598d4c1e6e607692b96364a42f
https://doi.org/10.1007/bf02735392
Zobrazit plný text záznamu
8
Action of Gold Sodium Thiomalate on Experimental Thrombosis In Vivo
Autor: H. E. Howard-Lock, D. Somers, Colin J. L. Lock, Janice Rischke, W. Watson Buchanan, M. G. Hogan, Walter F. Kean, Y. B. Kassam, L. Nablo
Publikováno v: Journal of Pharmaceutical Sciences. 80:113-118
In order to study the effect of gold compounds on the action of thrombin in vivo, experiments were performed to measure platelet survival and the weight of thrombus formation in experimental models of intra-aortic thrombosis by two indwelling aortic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676250f60015765c5bff8ed44784d56a
https://doi.org/10.1002/jps.2600800205
Zobrazit plný text záznamu
9
2R,4S-2-(2′-Methyl-3′-hydroxy-5′-hydroxymethylenepyridine-C4′)-5,5-dimethylthiazolidine-4-carboxylic acid, the product of the reaction of D-penicillamine and vitamin B6
Autor: Colin J. L. Lock, H. E. Howard-Lock, R. Orgias, Romolo Faggiani
Publikováno v: Canadian Journal of Chemistry. 69:1-7
We have studied the reaction of both D- and L-penicillamine with pyridoxal hydrochloride and examined the products by single crystal X-ray diffraction. The structure of the title compound, A, formed by the reaction of D-penicillamine and pyridoxal wa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e159f9d2ee08cb27787e5170ab79c64
https://doi.org/10.1139/v91-001
Zobrazit plný text záznamu
10
Monoammonium Bis(D-penicillaminato-S)aurate(I) 3.667-Hydrate
Autor: Colin J. L. Lock, Zhixian Wang, Daren J. LeBlanc, James F. Britten, H. E. Howard-Lock
Publikováno v: Acta Crystallographica Section C Crystal Structure Communications. 53:1763-1765
The anion of the title compound, (NH 4 )[Au(C 5 H 10 NO 2 S) 2 ].3.667H 2 O, has roughly linear coordination of the Au atom to the S atoms of the ligands [Au-S 2.2900(13)A and S-Au-S 178.47(7)°]. The C-S...S-C torsion angle is 29.3 (2)°. The packin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae657e30995edc20ca944aab99945ba5
https://doi.org/10.1107/s0108270197009724
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje