Zobrazeno 1 - 8
of 8
pro vyhledávání: '"H. E. Barksby"'
Autor:
John J. Taylor, RM Al-Shahwani, Katrin M. Jaedicke, Philip M. Preshaw, RC Davies, Paiboon Jitprasertwong, H. E. Barksby
Publikováno v:
Journal of Periodontal Research. 46:663-672
BACKGROUND AND OBJECTIVE: Complex relationships exist between diabetes and periodontal disease. Diabetes is accepted as a risk factor for periodontal disease, and recent evidence supports the existence of a bidirectional relationship between these tw
Publikováno v:
Clinical and Experimental Immunology. 156:479-487
Summary Porphyromonas gingivalis lipopolysaccharide (LPS) (strain W50) interacts with Toll-like receptor 2 (TLR-2) leading to cytokine expression and inflammation, and thereby plays a key role in the pathogenesis of periodontal disease. The aims of t
The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders
Publikováno v:
Clinical and Experimental Immunology. 149:217-225
Summary Understanding cytokine immunobiology is central to the development of rational therapies for destructive inflammatory diseases such as rheumatoid arthritis (RA) and periodontitis. The classical interleukin-1 (IL-1) family cytokines, IL-1α an
Autor:
Andrew D. Rowan, Carl D. Richards, Tim E. Cawston, H. E. Barksby, J. M. Milner, Wang Hui, Heiko Peters, Ilka Wappler
Publikováno v:
Arthritis & Rheumatism. 54:540-550
Objective To identify the genes up-regulated by interleukin-1 (IL-1) in combination with oncostatin M (OSM) in chondrocytes that may be involved in mechanisms of cartilage repair and degradation. Methods Gene microarray and real-time polymerase chain
Publikováno v:
Annals of the Rheumatic Diseases. 64:1624-1632
Objective: To determine whether oncostatin M (OSM) + tumour necrosis factor α (TNFα) induces aggrecanase activity in chondrocyte membranes, to determine the effects of transforming growth factor s1 (TGFs1), interleukin 4 (IL4), and tissue inhibitor
Autor:
R C, Davies, K M, Jaedicke, H E, Barksby, P, Jitprasertwong, R M, Al-Shahwani, J J, Taylor, P M, Preshaw
Publikováno v:
Journal of periodontal research. 46(6)
Complex relationships exist between diabetes and periodontal disease. Diabetes is accepted as a risk factor for periodontal disease, and recent evidence supports the existence of a bidirectional relationship between these two diseases. It has been hy
Autor:
Angela M. Patterson, T. Robson, Tim E. Cawston, H. E. Barksby, Jim Middleton, J. M. Milner, N. J. Peake, Wang Hui, Andrew D. Rowan, Carl D. Richards, Rachel L. Lakey
Publikováno v:
Arthritis and rheumatism. 54(10)
Objective We have previously reported the up-regulation of matrix metalloproteinase 10 (MMP-10) following treatment with the procatabolic stimulus of interleukin-1 (IL-1) and oncostatin M (OSM) in chondrocytes. Although MMP-10 is closely related to M
Autor:
H. E. Barksby, W. Hui, I. Wappler, H. H. Peters, J. M. Milner, C. D. Richards, T. E. Cawston, A. D. Rowan
Publikováno v:
Arthritis & Rheumatism; Feb2006, Vol. 54 Issue 2, p540-550, 11p