Zobrazeno 1 - 10
of 13
pro vyhledávání: '"H. Dudley Sinnett"'
Publikováno v:
The Breast. 14:419-424
Summary Objective : To review the mammographic and ultrasound appearances in patients who have invasive ductal carcinoma with a central acellular zone (ring carcinoma), as this feature has been reported to be associated with a poorer outcome. Materia
Autor:
Clare Peckitt, Samantha Fox, Nicholas C.P. Cross, Emma Hall, Helen Graham, Brendan M. Smith, Gopi Tripuraneni, Margreet Lüchtenborg, H. Dudley Sinnett, R. Charles Coombes, Anjana Singh, Martin J. Slade
Publikováno v:
International Journal of Cancer. 114:94-100
We have previously developed a quantitative PCR (QPCR) technique for the detection of cytokeratin 19 (CK19) transcripts in blood and bone marrow and compared this to immunocytochemistry (ICC). Together, both have shown promise for monitoring therapeu
Autor:
Sami Shousha, H. Dudley Sinnett
Publikováno v:
The Breast Journal. 10:150-153
Two recently seen patients presenting with large breast lumps that proved to be pure mesenchymal tumors arising from the underlying chest wall are presented. One tumor proved to be a giant cell tumor of soft tissue and the other an osteogenic sarcoma
Autor:
H. Dudley Sinnett, Brendan M. Smith, Helen Graham, Margreet Lüchtenborg, Jacqueline English, Martin J. Slade, Nicholas C.P. Cross, R. Charles Coombes
Publikováno v:
Journal of Clinical Oncology. 18:1432-1439
PURPOSE: We previously developed a quantitative system for the detection of cytokeratin 19 (CK-19) transcripts using reverse transcriptase polymerase chain reaction (PCR) to detect breast carcinoma cells in blood and bone marrow. The aim of this stud
Autor:
Dharsha Shivapatham, Hemant Singhal, Simak Ali, Jie Jiang, Dimitri Hadjiminas, R. Charles Coombes, Nigel Barrett, Martin J. Slade, David M. Vigushin, Andreas Polychronis, David Peston, Emma Beresford, Ken Morrison, Janine Mansi, Sami Shousha, H. Dudley Sinnett
Publikováno v:
The Lancet. Oncology. 6(6)
Summary Background Some oestrogen-receptor (ER) positive breast cancers express epidermal growth factor receptor (EGFR), but whether inhibition of EGFR can suppress proliferation of breast cancer cells and ER function is not known. Methods In a doubl
Autor:
Martin J, Slade, Anjana, Singh, Brendan M, Smith, Gopi, Tripuraneni, Emma, Hall, Clare, Peckitt, Samantha, Fox, Helen, Graham, Margreet, Lüchtenborg, H Dudley, Sinnett, Nicholas C P, Cross, R Charles, Coombes
Publikováno v:
International journal of cancer. 114(1)
We have previously developed a quantitative PCR (QPCR) technique for the detection of cytokeratin 19 (CK19) transcripts in blood and bone marrow and compared this to immunocytochemistry (ICC). Together, both have shown promise for monitoring therapeu
Autor:
Nicholas C.P. Cross, Brendan M. Smith, H. Dudley Sinnett, R. Charles Coombes, Martin J. Slade
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 17(3)
PURPOSE: Previous reports have indicated that reverse transcriptase polymerase chain reaction (RT-PCR) for cytokeratin 19 (CK-19) may be useful in the management of patients with breast cancer. However, the specificity of this technique is low, princ
Autor:
Ian Judson, Janet Hardy, Caroline L. Ellin, H. Dudley Sinnett, Trevor J. Powles, R. Charles Coombes, Sue Ashley
Publikováno v:
European journal of cancer (Oxford, England : 1990). 26(7)
Seventy-four post-menopausal women with metastatic breast cancer were treated with a combination hormonal regimen consisting of tamoxifen, aminoglutethimide danazol and medroxyprogesterone acetate (POND). 72% of the patients had received no previous
Autor:
Trevor J. Powles, Jane B. Davey, Mitchell Dowsett, Janet Hardy, H. Dudley Sinnett, Alan McKinna, Jennifer Treleaven, Colin R. Tillyer, Sue Ashley, David O. Cosgrove, A. G. Nash, Susan K. Rundle
Publikováno v:
Breast Cancer Research and Treatment. 14:23-31
The hypothesis that oestrogen is an important promoter of human breast cancer raises the possibility that endocrine intervention could prevent the disease. Various methods of reducing oestrogenic activity have been proposed including dietary control,
Autor:
P.A. Trott, G. Walsh, J. Alan McKinna, Clive Harmer, Roger A'Hern, Cyril Fisher, Ian E. Smith, Janine L. Mansi, H. Dudley Sinnett
Publikováno v:
European journal of cancerclinical oncology. 25(11)
Fifty-seven patients with large but potentially operable primary breast cancer were treated with primary medical therapy rather than initial mastectomy, using chemotherapy (15) or endocrine therapy (42) with the tumour remaining in situ . Of patients