Zobrazeno 1 - 10
of 654
pro vyhledávání: '"H. Drummond"'
Autor:
N. T. Ventham, N. A. Kennedy, A. T. Adams, R. Kalla, S. Heath, K. R. O'Leary, H. Drummond, IBD BIOM consortium, IBD CHARACTER consortium, D. C. Wilson, I. G. Gut, E. R. Nimmo, J. Satsangi
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Epigenetic perturbations may be an important factor in diseases where both genes and environment play a role. Here, Ventham and colleagues show that DNA methylation changes in inflammatory bowel disease are related to the underlying genotype, and are
Externí odkaz:
https://doaj.org/article/03f4cfccee3b45d1b75ae6adcb9da079
Publikováno v:
African Journal of Hospitality, Tourism and Leisure, Vol 11, Iss SE1, Pp 578-594 (2022)
Present-mindedness is a defining characteristic of the majority of research on niche tourism. In many respects this is unsurprising as interest in niche tourism has been driven by policy imperatives and potential contributions to destination developm
Externí odkaz:
https://doaj.org/article/192509582f9f4095a54f16412f65a80c
Autor:
Faith E. Davies, Gareth J. Morgan, Leon Hooftman, Alan H. Drummond, David Krige, Brian A. Walker, Alan S. Dunlop, Srikanth Muralikrishnan, Emma M. Smith, Emma L. Davenport, Hannah E. Moore
Myeloma cells are highly dependent on the unfolded protein response to assemble folded immunoglobulins correctly. Therefore, targeting protein handling within a myeloma cell by inhibiting the aminopeptidase enzyme system, which catalyses the hydrolys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac1a66c236bf11a16b5b187d19a3964
https://doi.org/10.1158/1535-7163.c.6531419.v1
https://doi.org/10.1158/1535-7163.c.6531419.v1
Autor:
Faith E. Davies, Gareth J. Morgan, Leon Hooftman, Alan H. Drummond, David Krige, Brian A. Walker, Alan S. Dunlop, Srikanth Muralikrishnan, Emma M. Smith, Emma L. Davenport, Hannah E. Moore
Supplementary Table from Aminopeptidase inhibition as a targeted treatment strategy in myeloma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f6e9e3991c493a06b86dec7e567b1c
https://doi.org/10.1158/1535-7163.22484465
https://doi.org/10.1158/1535-7163.22484465
Autor:
Alan H. Drummond, Andrew Ayscough, Elisabeth A. Bone, Suzanne A. Eccles, L. Michael Wood, Annette Wright, Rajesh Odedra, David Laber, Gary Box, Steve Wood, Thakor Patel, Jo Owen, Valérie Legris, Patricia Kirwin-Jones, Vanessa L. Clark, Stephen Chandler, Juliana Callaghan, Erica Stone, Lauren E.C. Miles, Hannah Farmer, Nicolas Flores, Lindsay J. Bawden, Lindsey A. Needham, David Krige
Supplementary Table 4 from CHR-2797: An Antiproliferative Aminopeptidase Inhibitor that Leads to Amino Acid Deprivation in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09283a6bb96997d03f13654b66fe6fa3
https://doi.org/10.1158/0008-5472.22373576
https://doi.org/10.1158/0008-5472.22373576
Autor:
Alan H. Drummond, Andrew Ayscough, Elisabeth A. Bone, Suzanne A. Eccles, L. Michael Wood, Annette Wright, Rajesh Odedra, David Laber, Gary Box, Steve Wood, Thakor Patel, Jo Owen, Valérie Legris, Patricia Kirwin-Jones, Vanessa L. Clark, Stephen Chandler, Juliana Callaghan, Erica Stone, Lauren E.C. Miles, Hannah Farmer, Nicolas Flores, Lindsay J. Bawden, Lindsey A. Needham, David Krige
CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacologically active acid product (CHR-79888) inside cells. CHR-79888 is a potent inhibitor of a number of intracellular aminopeptidases, including leucine aminopeptidase. CHR-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a2ca42194c35dcfa53e5c81a05d9b3
https://doi.org/10.1158/0008-5472.c.6497138
https://doi.org/10.1158/0008-5472.c.6497138
Autor:
Alan H. Drummond, Andrew Ayscough, Elisabeth A. Bone, Suzanne A. Eccles, L. Michael Wood, Annette Wright, Rajesh Odedra, David Laber, Gary Box, Steve Wood, Thakor Patel, Jo Owen, Valérie Legris, Patricia Kirwin-Jones, Vanessa L. Clark, Stephen Chandler, Juliana Callaghan, Erica Stone, Lauren E.C. Miles, Hannah Farmer, Nicolas Flores, Lindsay J. Bawden, Lindsey A. Needham, David Krige
Supplementary Methods and Materials from CHR-2797: An Antiproliferative Aminopeptidase Inhibitor that Leads to Amino Acid Deprivation in Human Leukemic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03cde35dbe728b3cd9eede6ce467677c
https://doi.org/10.1158/0008-5472.22373582
https://doi.org/10.1158/0008-5472.22373582
Publikováno v:
Behavioral Ecology and Sociobiology. 76
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Akademický článek
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