Zobrazeno 1 - 10
of 127
pro vyhledávání: '"H. Diana Rosas"'
Autor:
Patrick Lao, Natalie Edwards, Lisi Flores-Aguilar, Mohamad Alshikho, Batool Rizvi, Dana Tudorascu, H. Diana Rosas, Michael Yassa, Bradley T. Christian, Mark Mapstone, Benjamin Handen, Molly E. Zimmerman, Jose Gutierrez, Donna Wilcock, Elizabeth Head, Adam M. Brickman
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Adults with Down syndrome have a genetic form of Alzheimer’s disease (AD) and evidence of cerebrovascular disease across the AD continuum, despite few systemic vascular risk factors. The onset and progression of AD in Down syndrome is high
Externí odkaz:
https://doaj.org/article/4a432bd6f9aa4c0fbc74fe1536e6faa9
Autor:
Emily K. Schworer, Benjamin L. Handen, Melissa Petersen, Sid O'Bryant, Jamie C. Peven, Dana L. Tudorascu, Laisze Lee, Sharon J. Krinsky‐McHale, Christy L. Hom, Isabel C. H. Clare, Bradley T. Christian, Nicole Schupf, Joseph H. Lee, Elizabeth Head, Mark Mapstone, Ira Lott, Beau M. Ances, Shahid Zaman, Adam M. Brickman, Florence Lai, H. Diana Rosas, Sigan L. Hartley, the Alzheimer Biomarker Consortium‐Down Syndrome
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION People with Down syndrome (DS) have a 75% to 90% lifetime risk of Alzheimer's disease (AD). AD pathology begins a decade or more prior to onset of clinical AD dementia in people with DS. It is not clear if plasma biomarkers of A
Externí odkaz:
https://doaj.org/article/13dbf3a21419485bb2909612d2c5af23
Autor:
Natalie DiProspero, Mithra Sathishkumar, John Janecek, Anna Smith, Liv McMillan, Melissa Petersen, Nicholas Tustison, David B. Keator, Eric Doran, Christy L. Hom, Dana Nguyen, Howard Andrews, Sharon Krinsky‐McHale, Adam M. Brickman, H. Diana Rosas, Florence Lai, Elizabeth Head, Mark Mapstone, Wayne Silverman, Ira T. Lott, Sid O'Bryant, Michael A. Yassa
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract INTRODUCTION Virtually all people with Down syndrome (DS) develop neuropathology associated with Alzheimer's disease (AD). Atrophy of the hippocampus and entorhinal cortex (EC), as well as elevated plasma concentrations of neurofilament ligh
Externí odkaz:
https://doaj.org/article/7422d877af6a4072bb0972d4b84616f7
Autor:
Ali Demir, H. Diana Rosas
Publikováno v:
Neuroimage: Reports, Vol 3, Iss 2, Pp 100174- (2023)
The corpus callosum (CC) is one of the most important interhemispheric white matter tracts that connects interrelated regions of the cerebral cortex. Its disruption has been investigated in previous studies and has been found to play an important rol
Externí odkaz:
https://doaj.org/article/a2076e79cf2e476eb9ffd221ec682b88
Autor:
David Mengel, Wen Liu, Robert J. Glynn, Dennis J. Selkoe, Andre Strydom, Florence Lai, H. Diana Rosas, Amy Torres, Vasiliki Patsiogiannis, Brian Skotko, Dominic M. Walsh
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Down syndrome (DS) is the most common genetic cause of Alzheimer’s disease (AD), but diagnosis of AD in DS is challenging due to the intellectual disability which accompanies DS. When disease-modifying agents for AD are approved
Externí odkaz:
https://doaj.org/article/765d7c94e9064dc89f729ff61c72457b
Autor:
H. Diana Rosas, Lydia R. Lewis, Nathaniel D. Mercaldo, Shahin Nasr, Adam M. Brickman, Viviana Siless, Michael Yassa, Mithra Sathishkumar, Ira Lott, Nicole Schupf, Wayne Silverman, Florence Lai, the Alzheimer's Disease in Down Syndrome (ADDS) Consortium
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Most individuals with Down syndrome (DS) have the neuropathological changes of Alzheimer's disease (AD) by age 40 and will have developed dementia by age 60. Alterations of the intrinsic connectivity of the default mode network
Externí odkaz:
https://doaj.org/article/7b450d28ff07496abbab6db8053073bb
Autor:
Michael S. Rafii, Beau M. Ances, Nicole Schupf, Sharon J. Krinsky‐McHale, Mark Mapstone, Wayne Silverman, Ira Lott, William Klunk, Elizabeth Head, Brad Christian, Florence Lai, H. Diana Rosas, Shahid Zaman, Melissa E. Petersen, Andre Strydom, Juan Fortea, Benjamin Handen, Sid O'Bryant
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract The National Institute on Aging in conjunction with the Alzheimer's Association (NIA‐AA) recently proposed a biological framework for defining the Alzheimer's disease (AD) continuum. This new framework is based upon the key AD biomarkers (
Externí odkaz:
https://doaj.org/article/26343955218246fdbf706ffb828d3c44
Autor:
Melissa E. Petersen, Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone, Amrita Cheema, Wayne Silverman, Ira Lott, Michael S. Rafii, Benjamin Handen, William Klunk, Elizabeth Head, Brad Christian, Tatiana Foroud, Florence Lai, H. Diana Rosas, Shahid Zaman, Beau M. Ances, Mei‐Cheng Wang, Benjamin Tycko, Joseph H. Lee, Sid O'Bryant, the Alzheimer's Biomarker Consortium – Down Syndrome (ABC‐DS)
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Previously generated serum and plasma proteomic profiles were examined among adults with Down syndrome (DS) to determine whether these profiles could discriminate those with mild cognitive impairment (MCI‐DS) and Alzheimer's d
Externí odkaz:
https://doaj.org/article/6198ea4b42bc4c93a83dd033c6ae686d
Autor:
Margaret B. Pulsifer, Casey L. Evans, Christy Hom, Sharon J. Krinsky‐McHale, Wayne Silverman, Florence Lai, Ira Lott, Nicole Schupf, Jiyang Wen, H. Diana Rosas
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Adults with Down syndrome (DS) are at high risk for early onset Alzheimer's disease (AD), characterized by a progressive decline in multiple cognitive domains including language, which can impact social interactions, behavior, a
Externí odkaz:
https://doaj.org/article/6dfef41ad0e447f28b6b439868dfab74
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)
Abstract Introduction Adults with Down syndrome (DS) older than 40 have Alzheimer's disease (AD) neuropathology and high risk for dementia, but little is known about the relationship of sex to AD risk in this population. Methods Using nonparametric m
Externí odkaz:
https://doaj.org/article/a6d68a7b44854998b0a3181c5d0aeb80