Zobrazeno 1 - 10 of 129 pro vyhledávání: '"H. Des Abbayes"'
1
Biodistribution study of phosphonolipids: a class of non-viral vectors efficient in mice lung-directed gene transfer
Autor: F. Berthou, A. Le Pape, Claude Férec, Jean-Jacques Yaouanc, Pascal Delépine, J.‐C. Clement, Tristan Montier, Christine Guillaume, H. Des Abbayes
Publikováno v: The Journal of Gene Medicine. 5:600-608
Background A multitude of cationic lipids have been synthesized since they were first proposed for use in gene therapy. Cationic lipids are able to efficiently transfect cells both in vitro and in vivo. Whereas most research groups have focused their
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f8d84da4684508ff4a34c1ade638de2
https://doi.org/10.1002/jgm.385
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2
Cationic Phosphonolipids as Nonviral Gene Transfer Agents in the Lungs of Mice
Autor: Jean-Jacques Yaouanc, J.P. Leroy, E Gobin, Claude Férec, Virginie Floch, J.‐C. Clement, Marie-Pierre Audrézet, Bernard Mercier, H. Des Abbayes, G Le Bolch, V Morin, C Guillaume-Gable
Publikováno v: Human Gene Therapy. 9:2309-2319
With the aim of developing new gene transfer tools for treating CF with gene therapy, we have synthesized a novel family of molecules named cationic phosphonolipids. The most efficient among them were selected by in vitro screening to compare their a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6656e3ad4131717285f91a3e25f5007
https://doi.org/10.1089/hum.1998.9.16-2309
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3
Transgene expression kinetics after transfection with cationic phosphonolipids in hematopoietic non adherent cells
Autor: E Gobin, Jean-François Abgrall, G Le Bolch, J.P. Leroy, Christine Guillaume, H. Des Abbayes, Jean-Jacques Yaouanc, Marie-Pierre Audrézet, Bernard Mercier, Virginie Floch, J.‐C. Clement, Claude Férec
Publikováno v: Biochimica et Biophysica Acta:Biomembranes
Biochimica et Biophysica Acta:Biomembranes, Elsevier, 1998, 1371, pp.53--70. ⟨10.1016/S0005-2736(98)00002-9⟩
International audience; Cationic lipids are considered to be capable of efficiently and safely mediating DNA transfer into cells, although expression is transient. A new family of cationic lipids, called phosphonolipids, has been developed, with the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7860e1e7a9abdedd528d8643cde798dc
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4
Novel Cationic Phosphonolipids Agents for in Vitro Gene Transfer to Epithelial Cell Lines
Autor: Jean-Jacques Yaouanc, Arpita Paul, Claude Férec, Virginie Floch, J.‐C. Clement, G Le Bolch, Marie-Pierre Audrézet, Bernard Mercier, H. Des Abbayes
Publikováno v: Journal of Liposome Research. 7:273-300
The use of cationic liposomes is one of the main approaches currently investigated to introduce into a cell a gene with therapeutic properties. This study presents in vitro results obtained with a new family of gene transfer agents, the phosphonolipi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67024dd0a76a7d1ac167c3017e12ed62
https://doi.org/10.3109/08982109709035502
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6
Mono N-alkylation and N-acylation of cyclen and cyclam via their metaltricarbonyl complexes (M = Cr, Mo)
Autor: J.‐C. Clement, Véronique Patinec, Henri Handel, Jean-Jacques Yaouanc, H. Des Abbayes
Publikováno v: Tetrahedron Letters. 36:79-82
Reaction of metaltricarbonyl complexes of cyclen and cyclam with enolisable aldehydes or acid chlorides yields, after removal of the protecting M(CO) 3 moiety, selectively mono N-functionalized derivatives.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c340b9653506190e25dac3bc3315a2d6
https://doi.org/10.1016/0040-4039(94)02157-7
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