Zobrazeno 1 - 10
of 20
pro vyhledávání: '"H. D. Shine"'
Autor:
H. D. Shine, Brian J. Baumgartner
Publikováno v:
Journal of Neuroscience Research. 54:766-777
Axotomy of peripheral nerves in neonatal rats induces motoneuron death that can be delayed but not arrested by the application of several neurotrophic factors (NFs) or adenoviral vectors carrying genes for NFs. We tested whether an adenoviral vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e438f3d8f5f27a4c0976039a93e99fda
https://doi.org/10.1002/(sici)1097-4547(19981215)54:6<766::aid-jnr4>3.0.co
https://doi.org/10.1002/(sici)1097-4547(19981215)54:6<766::aid-jnr4>3.0.co
Autor:
Savio L. C. Woo, Sheng Chen, Philip R. Wyde, Estuardo Aguilar-Cordova, Jerry C. Goodman, Robert G. Grossman, H. D. Shine
Publikováno v:
Gene Therapy. 4:275-279
The neurotoxicity of an adenoviral vector (Adv.RSVtk) carrying the gene for herpes simplex virus thymidine kinase (HSVtk) was tested in the cotton rat, a semipermissive host. Adv.RSVtk was injected intracerebrally in cotton rats at a dose of 5.0 x 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24822f09dcad6d220a1212756300c9d
https://doi.org/10.1038/sj.gt.3300397
https://doi.org/10.1038/sj.gt.3300397
Autor:
Savio L. C. Woo, Jerry C. Goodman, Sheng Chen, Robert G. Grossman, M. J. Perez-Cruet, H. D. Shine, Todd Trask
Publikováno v:
Journal of Neuroscience Research. 39:506-511
The efficacy of adenovirus (ADV)-mediated gene therapy to treat brain tumors was tested in a syngeneic glioma model. Tumor cells were transduced in situ with a replication-defective ADV carrying the herpes simplex virus thymidine kinase (HSV-tk) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7485ec272220cf8fc92edca35fa365
https://doi.org/10.1002/jnr.490390417
https://doi.org/10.1002/jnr.490390417
Publikováno v:
Journal of Neuroscience Research. 34:257-264
To study the effect of SV40 large T-antigen expression in myelin-forming cells of both the central and peripheral nervous system, a series of transgenic mice were generated expressing the SV40 large T-antigen under control of the myelin basic protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d479384a1459760a81e616acded806
https://doi.org/10.1002/jnr.490340302
https://doi.org/10.1002/jnr.490340302
Autor:
L.A. Mamounas, M.H. Grider, W-D. Le, H. D. Shine, D. A. Menesses-Diaz, Lijun Zhou, X. Zheng, L. R. McGowen
Publikováno v:
Journal of Neurochemistry. 81:85-86
A successful treatment for spinal cord injury (SCI) must include means to induce axonal regeneration and synaptogenesis. Though much research has demonstrated the effectiveness of neurotrophic factors (NFs) in supporting axonal regeneration, systemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b4625643c8cbaaf7b4bfacb1ea20310
https://doi.org/10.1046/j.1471-4159.81.s1.54_5.x
https://doi.org/10.1046/j.1471-4159.81.s1.54_5.x
Autor:
B J, Baumgartner, H D, Shine
Publikováno v:
Journal of neuroscience research. 54(6)
Axotomy of peripheral nerves in neonatal rats induces motoneuron death that can be delayed but not arrested by the application of several neurotrophic factors (NFs) or adenoviral vectors carrying genes for NFs. We tested whether an adenoviral vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::848835b7670be27f8f3bd24a710b8fc9
https://pubmed.ncbi.nlm.nih.gov/9856860
https://pubmed.ncbi.nlm.nih.gov/9856860
Autor:
Brian J. Baumgartner, H D Shine
Application of neurotrophic factors (NFs) to the cut stump of motor nerves of neonatal rats confers neuroprotection from trauma-induced neuronal death. To test whether motoneurons are capable of responding to endogenously produced NFs, facial motoneu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16206921039752ba35eeecc6d21c11ed
https://europepmc.org/articles/PMC6573127/
https://europepmc.org/articles/PMC6573127/
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 16(16)
Axon caliber may be influenced by intrinsic neuronal factors and extrinsic factors related to myelination. To understand these extrinsic influences, we studied how axon-caliber expansion is related to changes in neurofilament and microtubule organiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74b92a267f201faa60cdab7df10caa14
https://pubmed.ncbi.nlm.nih.gov/8756439
https://pubmed.ncbi.nlm.nih.gov/8756439
Autor:
Robert G. Grossman, G. B. Hubbard, D. A. Carrier, S. Rajagopalan, E. Aguilar-Cordova, Todd Trask, Shu-Hsia Chen, H. D. Shine, Jerry C. Goodman, K. D. Carey, Savio L. C. Woo
Publikováno v:
Human gene therapy. 7(10)
Transduction of experimental gliomas with the herpes simplex virus thymidine kinase gene (HSV-tk) using a replication-defective adenoviral vector (ADV/RSV-tk) confers sensitivity to ganciclovir (GCV) leading to tumor destruction and prolonged host su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b27b1207e4ac87988214c77087edf1
https://pubmed.ncbi.nlm.nih.gov/8793548
https://pubmed.ncbi.nlm.nih.gov/8793548
Autor:
Jerry C. Goodman, Savio L. C. Woo, Shu-Hsia Chen, Robert G. Grossman, Ahmet Çolak, H. D. Shine
Publikováno v:
Human gene therapy. 6(10)
We investigated the therapeutic efficacy of adenovirus-mediated gene therapy to treat malignant mammary tumors in vitro and in vivo in the brain. A mammary adenocarcinoma cell line derived from Fischer rats (13762 MAT B III; MAT-B) was used. In vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3387fe1d574fda00aeecc020cc8b48a0
https://pubmed.ncbi.nlm.nih.gov/8590736
https://pubmed.ncbi.nlm.nih.gov/8590736