Zobrazeno 1 - 10
of 10
pro vyhledávání: '"H. D. GILES"'
Publikováno v:
Toxicological Sciences. 17:159-176
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 45(1)
Combination therapy with anti-HIV drugs and opportunistic infection drugs is a common practice in treatment of AIDS patients. Although toxic effects of most individual therapies are known, the toxic potential of most combination therapies has not bee
Publikováno v:
Cancer research. 56(20)
2',3'-dideoxycytidine (ddC) is a synthetic pyrimidine nucleoside analogue approved for treatment of HIV-positive patients. Previous studies indicated that ddC has the potential to cause thymic lymphoma in C57BL/6 x C3H F1 (hereafter called B6C3F1) mi
Autor:
C, Lindamood, D R, Farnell, H D, Giles, J D, Prejean, J J, Collins, K, Takahashi, R R, Maronpot
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 19(1)
The purpose of this study was to evaluate the toxicity of t-butyl alcohol, an important commodity chemical, an additive to unleaded gasoline, and a contaminant of drinking water. Ninety-day toxicity studies were conducted in B6C3F1 mice and Fischer 3
Autor:
C, Lindamood, F O, Cope, D L, Dillehay, M P, Everson, H D, Giles, E W, Lamon, D J, McCarthy, J L, Sartin, D L, Hill
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(1)
Studies were conducted to define primary pharmacological and toxicological properties of two arotinoids, SMR-2 and SMR-6, in male B6D2F1 mice. Mice were gavaged daily for up to 22 days with retinoids in corn oil (0.1, 0.2, or 0.4 mg/kg day SMR-2 or S
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 12(3)
Menhaden oil, which has hypolipidemic and anticarcinogenic activity, reduces the hypertriglyceridemia caused by retinyl acetate. Male Sprague-Dawley rats were dosed daily for 30 days by gavage with either corn oil (CO); menhaden oil (MO); 20, 80, and
Publikováno v:
Cancer treatment reports. 63(8)
Publikováno v:
Veterinary pathology. 25(1)
Tissue sections and records of 56 rats with chordoma, identified in the National Toxicology Program's (NTP) data base of approximately 115,000 rats, were examined to determine morphological characteristics, incidence, and aspects of biological behavi
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 8(4)
Arotinoids, which are analogs of retinoic acid (RA) and retinol (RO) with the carbon skeleton in a rigid conformation, have more favorable therapeutic indices relative to all-trans-RA and all-trans-RO. The purpose of this investigation was to obtain
Autor:
B T, Robertson, H D, Giles
Publikováno v:
Journal of the American Veterinary Medical Association. 161(2)