Zobrazeno 1 - 10
of 129
pro vyhledávání: '"H. Criss Hartzell"'
Autor:
Alec A. Schmaier, Papa F. Anderson, Siyu M. Chen, Emale El-Darzi, Ivan Aivasovsky, Milan P. Kaushik, Kelsey D. Sack, H. Criss Hartzell, Samir M. Parikh, Robert Flaumenhaft, Sol Schulman
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Endothelial cells (ECs) normally form an anticoagulant surface under physiological conditions, but switch to support coagulation following pathogenic stimuli. This switch promotes thrombotic cardiovascular disease. To generate thrombin at physiologic
Externí odkaz:
https://doaj.org/article/9e71fa5130a2448fa08eb8ede82391f7
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229041 (2020)
MethodsMuscle sections were stained for cell boundary (laminin) and myofiber type (myosin heavy chain isoforms). Myosoft, running in the open access software platform FIJI (ImageJ), was used to analyze myofiber size and type in transverse sections of
Externí odkaz:
https://doaj.org/article/1a0000fdbc7d46818924297362257edb
Publikováno v:
Am J Physiol Cell Physiol
Limb-girdle muscular dystrophy R12 (LGMD-R12) is caused by recessive mutations in the Anoctamin-5 gene ( ANO5, TMEM16E). Although ANO5 myopathy is not X-chromosome linked, we performed a meta-analysis of the research literature and found that three-q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d623ffd77c7db7262e1191944de9870
https://doi.org/10.1152/ajpcell.00350.2021
https://doi.org/10.1152/ajpcell.00350.2021
Publikováno v:
eLife, Vol 6 (2017)
From bacteria to mammals, different phospholipid species are segregated between the inner and outer leaflets of the plasma membrane by ATP-dependent lipid transporters. Disruption of this asymmetry by ATP-independent phospholipid scrambling is import
Externí odkaz:
https://doaj.org/article/647ac68601fe4128ab845db07b947def
Autor:
Skylar ID Fisher, H Criss Hartzell
Publikováno v:
eLife, Vol 6 (2017)
Cryo-electron microscopy reveals the structure of a chloride channel that is closely related to a protein that transports lipids.
Externí odkaz:
https://doaj.org/article/48dcd18b3ee142b488778f45c9927975
Autor:
Trisha Lala, Juleva K. Doan, Hiroyuki Takatsu, H. Criss Hartzell, Hye-Won Shin, Randy A. Hall
Publikováno v:
Journal of Biological Chemistry. 298:102685
Brain-specific angiogenesis inhibitor 1 (BAI1; also called ADGRB1 or B1) is an adhesion G protein-coupled receptor known from studies on macrophages to bind to phosphatidylserine (PS) on apoptotic cells via its N-terminal thrombospondin repeats. A se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf8e75a5e95fb0c38764fdef5edf9d2
https://doi.org/10.1016/j.jbc.2022.102685
https://doi.org/10.1016/j.jbc.2022.102685
Publikováno v:
eLife, Vol 4 (2015)
Phospholipid scrambling (PLS) is a ubiquitous cellular mechanism involving the regulated bidirectional transport of phospholipids down their concentration gradient between membrane leaflets. ANO6/TMEM16F has been shown to be essential for Ca2+-depend
Externí odkaz:
https://doaj.org/article/5549572609ba4bd18256773581c27d21
Publikováno v:
Proceedings of the National Academy of Sciences. 116:19952-19962
ANO1 (TMEM16A) is a Ca2+-activated Cl- channel that regulates diverse cellular functions including fluid secretion, neuronal excitability, and smooth muscle contraction. ANO1 is activated by elevation of cytosolic Ca2+ and modulated by phosphatidylin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38efdfca0cd97a3bc32c4f8e000d6612
https://doi.org/10.1073/pnas.1904012116
https://doi.org/10.1073/pnas.1904012116
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58875 (2013)
Cell swelling induced by hypo-osmotic stress results in activation of volume-regulated anion channels (VRAC) that drive a compensatory regulatory volume decrease. We have previously shown that the Best1 gene in Drosophila encodes a VRAC that is also
Externí odkaz:
https://doaj.org/article/9b0b4356f72f4676b185257e3618bed8
Publikováno v:
The Journal of Cell Biology
Mutations in ANO5 cause a limb-girdle muscular dystrophy characterized by membrane repair defects that make muscles more susceptible to permanent damage from normal use. This work links failed membrane repair in ANO5-deficient muscle to altered traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf7669620e6b0787419edf07aacffc4
https://pubmed.ncbi.nlm.nih.gov/33496727
https://pubmed.ncbi.nlm.nih.gov/33496727