Zobrazeno 1 - 10
of 60
pro vyhledávání: '"H. Creemers"'
Autor:
Debbie S. Deben, Rob H. Creemers, Arjan J. van Adrichem, Roosmarie Drent, Audrey H. H. Merry, Mathie P. G. Leers, Adriaan A. van Bodegraven, Dennis R. Wong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The thiopurine derivatives azathioprine (AZA), mercaptopurine (MP) and tioguanine (TG) remain standard treatment of inflammatory bowel disease (IBD). The immune suppressive effect of thiopurines is primarily based on blocking the Ras-related
Externí odkaz:
https://doaj.org/article/86bc34ef56764200be389c6b655d2aa3
Autor:
Debbie S. Deben, Luc J. J. Derijks, Bianca J. C. van den Bosch, Rob H. Creemers, Annick van Nunen, Adriaan A. van Bodegraven, Dennis R. Wong
Publikováno v:
Metabolites, Vol 13, Iss 10, p 1054 (2023)
Tioguanine is metabolised by fewer enzymatic steps compared to azathioprine and mercaptopurine, without generating 6-methylmercaptopurine ribonucleotides. However, thiopurine S-methyl transferase (TPMT) plays a role in early toxicity in all thiopurin
Externí odkaz:
https://doaj.org/article/5fbf9405476044e988f385599d3ddcd0
Autor:
Merve Sivridaş, Rob H. Creemers, Dennis R. Wong, Paul J. Boekema, Tessa E. H. Römkens, Lennard P. L. Gilissen, Adriaan A. van Bodegraven, Floris C. Loeff, Theo Rispens, Luc J. J. Derijks
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 972 (2023)
There are limited data on therapeutic drug monitoring (TDM) in inflammatory bowel disease (IBD) patients treated with vedolizumab (VDZ). Although an exposure–response relation has been demonstrated in the post-induction phase, this relationship is
Externí odkaz:
https://doaj.org/article/935e6f04083545d584795100813406b1
Autor:
Phoebe Heenan, Rob H. Creemers, Shriya Sharma, Jacqueline Keenan, Simone Bayer, Wayne Young, Janine Cooney, Kelly Armstrong, Karl Fraser, Paula M. Skidmore, Nicholas J. Talley, Nicole Roy, Richard B. Gearry
Publikováno v:
Inflammatory Intestinal Diseases, Vol 5, Iss 3, Pp 132-143 (2020)
Background and aims: This cross-sectional observational case-control study was initiated in July 2016 with the aim of increasing an understanding of the underlying disease mechanisms in functional gastrointestinal disorders (FGIDs) including irritabl
Externí odkaz:
https://doaj.org/article/80144aa091cb4dbcbcf5b5a95c2b2c4d
Autor:
Rob H Creemers, Ashkan Rezazadeh Ardabili, Daisy M Jonkers, Mathie P G Leers, Mariëlle J Romberg-Camps, Marie J Pierik, Ad A van Bodegraven
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0258271 (2021)
ObjectiveData on the course of severe COVID-19 in inflammatory bowel disease (IBD) patients remains limited. We aimed to determine the incidence rate and clinical course of severe COVID-19 in the heavily affected South-Limburg region in the Netherlan
Externí odkaz:
https://doaj.org/article/b08a7013f9574e53a736557758fdb14c
Autor:
Sofia A. W. van Moorsel, Debbie S. Deben, Rob H. Creemers, Bjorn Winkens, Paul Bus, Marieke J. Pierik, Melek Simsek, Nanne K. H. de Boer, Adriaan A. van Bodegraven, Dennis R. Wong
Publikováno v:
van Moorsel, S A W, Deben, D S, Creemers, R H, Winkens, B, Bus, P, Pierik, M J, Simsek, M, de Boer, N K H, van Bodegraven, A A & Wong, D R 2022, ' Predictive Algorithm for Thiopurine-Induced Hepatotoxicity in Inflammatory Bowel Disease Patients ', Therapeutic Drug Monitoring, vol. 44, no. 6, pp. 747-754 . https://doi.org/10.1097/FTD.0000000000001031
Therapeutic Drug Monitoring, 44(6), 747-754. LIPPINCOTT WILLIAMS & WILKINS
Therapeutic Drug Monitoring, 44(6), 747-754. Lippincott Williams and Wilkins
Therapeutic Drug Monitoring, 44(6), 747-754. LIPPINCOTT WILLIAMS & WILKINS
Therapeutic Drug Monitoring, 44(6), 747-754. Lippincott Williams and Wilkins
BACKGROUND: Approximately 25% of patients with inflammatory bowel disease (IBD) discontinue azathioprine (AZA) or mercaptopurine (MP) therapy within 3 months of treatment initiation due to adverse drug reactions. Of these side-effects, about half are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1762b9e57e970c9f0c6f875b45af6234
http://www.scopus.com/inward/record.url?scp=85141934898&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85141934898&partnerID=8YFLogxK
Publikováno v:
Journal of Crohn's and Colitis.
Introduction The traditional long-term treatment goal of Crohn’s disease(CD) is maintenance of corticosteroid free clinical remission. Additional treatment targets, such as biochemical, endoscopic, and patient reported remission, are advocated. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9131ff5d7bdc051127bc1acf5001dc79
https://doi.org/10.1093/ecco-jcc/jjad037
https://doi.org/10.1093/ecco-jcc/jjad037
Autor:
Tessa Straatmijer, Vince B.C. Biemans, Marijn Visschedijk, Frank Hoentjen, Annemarie de Vries, Adriaan A. van Bodegraven, Alexander Bodelier, Nanne K.H. de Boer, Gerard Dijkstra, Noortje Festen, Carmen Horjus, Jeroen M. Jansen, Bindia Jharap, Wout Mares, Fiona D.M. van Schaik, Cyriel Ponsioen, Tessa Romkens, Nidhi Srivastava, Michael M.P. J.A. van der Voorn, Rachel West, Janneke van der Woude, Marije D.J. Wolvers, Marieke Pierik, Andrea E. van der Meulen-de Jong, Marjolijn Duijvestein, Malena Schlotter, Martine van Workum, Dirk de Jong, Willemijn van Dop, S. van der Marel, Hayat El Ghabzouri, Kamila Talhaoui, Bas Oldenburg, Nynke Boontje, Herma Fidder, Meike Hirdes, Rob H. Creemers, J. Hoekstra, Jael Smid, Zlatan Mujagic, Marthe François-Verweij, Toos Schakel- van den Berge, Jeroen Maljaars, Rosaline Theeuwen, Denise van den Berg, Suzanne Gerretsen, Xenia Yocarini, Geert D’Haens, Mark Lowenberg, Joep Grootjans, Krisztina Gecse, Gerd Bouma, Petra Waaijenberg, Bart Muskens
Publikováno v:
Clinical Gastroenterology and Hepatology, 21(1), 182-191.e2. ELSEVIER SCIENCE INC
Clinical Gastroenterology and Hepatology, 21, 1, pp. 182-191.e2
Clinical Gastroenterology and Hepatology, 21(1), 182-191.e2. W.B. Saunders Ltd
Clinical Gastroenterology and Hepatology, 21, 182-191.e2
Clinical gastroenterology and hepatology. Elsevier Science
Clinical gastroenterology and hepatology, 21(1), 182-191.e2. W.B. Saunders Ltd
Initiative on Crohn and Colitis 2023, ' Superior Effectiveness of Tofacitinib Compared to Vedolizumab in Anti-TNF-experienced Ulcerative Colitis Patients : A Nationwide Dutch Registry Study ', Clinical Gastroenterology and Hepatology, vol. 21, no. 1, pp. 182-191.e2 . https://doi.org/10.1016/j.cgh.2022.04.038
Clinical Gastroenterology and Hepatology, 21(1), 182-191.e2. W.B. Saunders
Clinical Gastroenterology and Hepatology, 21, 1, pp. 182-191.e2
Clinical Gastroenterology and Hepatology, 21(1), 182-191.e2. W.B. Saunders Ltd
Clinical Gastroenterology and Hepatology, 21, 182-191.e2
Clinical gastroenterology and hepatology. Elsevier Science
Clinical gastroenterology and hepatology, 21(1), 182-191.e2. W.B. Saunders Ltd
Initiative on Crohn and Colitis 2023, ' Superior Effectiveness of Tofacitinib Compared to Vedolizumab in Anti-TNF-experienced Ulcerative Colitis Patients : A Nationwide Dutch Registry Study ', Clinical Gastroenterology and Hepatology, vol. 21, no. 1, pp. 182-191.e2 . https://doi.org/10.1016/j.cgh.2022.04.038
Clinical Gastroenterology and Hepatology, 21(1), 182-191.e2. W.B. Saunders
Background & Aims: Clinicians face difficulty in when and in what order to position biologics and Janus kinase inhibitors in patients with anti-tumor necrosis factor-alpha (TNF) refractory ulcerative colitis (UC). We aimed to compare the effectivenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c5fd40e67e975df5ce34fd01d6aa67
https://research.rug.nl/en/publications/4d7e144b-6332-47f9-9cee-542a2092238d
https://research.rug.nl/en/publications/4d7e144b-6332-47f9-9cee-542a2092238d
Autor:
Femke Crouwel, Melek Simsek, Marjon A de Boer, Chris J J Mulder, Emma M van Andel, Rob H Creemers, Dirk P van Asseldonk, Ad A van Bodegraven, Carmen S Horjus, Marijn C Visschedijk, Angelique L M Weusthuis, Margien L Seinen, Bindia Jharap, Fiona D M van Schaik, Ishfaq Ahmad, Paul J Boekema, Greetje J Tack, Louktje Wormmeester, Maurice W M D Lutgens, Petra G A van Boeckel, Lennard P L Gilissen, Marjon Kerkhof, Maurice G V M Russel, Frank Hoentjen, Maartje E Bartelink, Johan P Kuijvenhoven, Jeroen W J Maljaars, Willemijn A van Dop, Janneke Wonders, Michael M P J A van der Voorn, Hans J C Buiter, Nanne K de Boer
Publikováno v:
Journal of Crohn's & colitis, 17(5), 738-745. Elsevier
Journal of Crohn's and Colitis. OXFORD UNIV PRESS
Journal of Crohn's and Colitis
Journal of Crohn's and Colitis, 17, 738-745
Crouwel, F, Simsek, M, de Boer, M A, Mulder, C J J, van Andel, E M, Creemers, R H, van Asseldonk, D P, van Bodegraven, A A, Horjus, C S, Visschedijk, M C, Weusthuis, A L M, Seinen, M L, Jharap, B, van Schaik, F D M, Ahmad, I, Boekema, P J, Tack, G J, Wormmeester, L, Lutgens, M W M D, van Boeckel, P G A, Gilissen, L P L, Kerkhof, M, Russel, M G V M, Hoentjen, F, Bartelink, M E, Kuijvenhoven, J P, Maljaars, J W J, van Dop, W A, Wonders, J, van der Voorn, M M P J A, Buiter, H J C & de Boer, N K 2023, ' Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease ', Journal of Crohn's & colitis, vol. 17, no. 5, pp. 738-745 . https://doi.org/10.1093/ecco-jcc/jjac183, https://doi.org/10.1093/ecco-jcc/jjac183
Journal of Crohn's and Colitis, 17, 5, pp. 738-745
Journal of Crohn's and Colitis. OXFORD UNIV PRESS
Journal of Crohn's and Colitis
Journal of Crohn's and Colitis, 17, 738-745
Crouwel, F, Simsek, M, de Boer, M A, Mulder, C J J, van Andel, E M, Creemers, R H, van Asseldonk, D P, van Bodegraven, A A, Horjus, C S, Visschedijk, M C, Weusthuis, A L M, Seinen, M L, Jharap, B, van Schaik, F D M, Ahmad, I, Boekema, P J, Tack, G J, Wormmeester, L, Lutgens, M W M D, van Boeckel, P G A, Gilissen, L P L, Kerkhof, M, Russel, M G V M, Hoentjen, F, Bartelink, M E, Kuijvenhoven, J P, Maljaars, J W J, van Dop, W A, Wonders, J, van der Voorn, M M P J A, Buiter, H J C & de Boer, N K 2023, ' Exposure to Thioguanine During 117 Pregnancies in Women With Inflammatory Bowel Disease ', Journal of Crohn's & colitis, vol. 17, no. 5, pp. 738-745 . https://doi.org/10.1093/ecco-jcc/jjac183, https://doi.org/10.1093/ecco-jcc/jjac183
Journal of Crohn's and Colitis, 17, 5, pp. 738-745
Background Safety of thioguanine in pregnant patients with inflammatory bowel disease [IBD] is sparsely recorded. This study was aimed to document the safety of thioguanine during pregnancy and birth. Methods In this multicentre case series, IBD pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5eec57469089c4cf6a4da189d0a517
https://hdl.handle.net/1887/3593862
https://hdl.handle.net/1887/3593862
Autor:
Wayne Young, Janine M. Cooney, Karl Fraser, Richard B. Gearry, Paula M L Skidmore, Nicholas J Talley, Rob H Creemers, Jacqueline I. Keenan, Nicole C. Roy, Kelly M. Armstrong, Simone Bayer, Phoebe Heenan, Shriya Sharma
Publikováno v:
Inflammatory Intestinal Diseases, Vol 5, Iss 3, Pp 132-143 (2020)
Inflamm Intest Dis
Inflamm Intest Dis
Background and aims: This cross-sectional observational case-control study was initiated in July 2016 with the aim of increasing an understanding of the underlying disease mechanisms in functional gastrointestinal disorders (FGIDs) including irritabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72621a4e21083c13832b6ddbef12990c
https://doi.org/10.1159/000508160
https://doi.org/10.1159/000508160