Zobrazeno 1 - 10
of 108
pro vyhledávání: '"H. Cool"'
Autor:
Shanshan Song, Bin Liu, Habibie Habibie, Jelle van den Bor, Martine J. Smit, Reinoud Gosens, Xinhui Wu, Corry-Anke Brandsma, Robbert H. Cool, Hidde J. Haisma, Gerrit J. Poelarends, Barbro N. Melgert
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103412- (2021)
Background: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MI
Externí odkaz:
https://doaj.org/article/a7399c7a248040bd8afada968c7d249c
Autor:
Jinfeng Shao, Bastiaan P. Kuiper, Andy-Mark W. H. Thunnissen, Robbert H. Cool, Liang Zhou, Chenxi Huang, Bauke W. Dijkstra, Jaap Broos
Publikováno v:
Journal of the American Chemical Society, 144(30):04986, 13815-13822. AMER CHEMICAL SOC
Journal of the American Chemical Society 144(30), 13815-13822 (2022). doi:10.1021/jacs.2c04986
Journal of the American Chemical Society 144(30), 13815-13822 (2022). doi:10.1021/jacs.2c04986
Journal of the American Chemical Society 144(30), 13815 - 13822 (2022). doi:10.1021/jacs.2c04986
In proteins, the amino acids Phe, Tyr, and especially Trp are frequently involved in π interactions such as $π–π$, cation−$π$, and CH−$π$
In proteins, the amino acids Phe, Tyr, and especially Trp are frequently involved in π interactions such as $π–π$, cation−$π$, and CH−$π$
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dffa154ce31011240397343ae48b1d6
https://doi.org/10.1021/jacs.2c04986
https://doi.org/10.1021/jacs.2c04986
Autor:
Steven de Jong, Ate G.J. van der Zee, Afshin Samali, Wim J. Quax, Robbert H. Cool, Go M. van Dam, Marjolijn N. Lub-de Hooge, Harry Hollema, Wytske Boersma-van Ek, Gert Jan Meersma, Devalingam Mahalingam, Elisabeth G.E. de Vries, Evelien W. Duiker
Purpose: Recombinant human tumor necrosis factor-related apoptosis-inducing ligand (rhTRAIL) is clinically evaluated as novel anticancer drug. rhTRAIL-DR5, a rhTRAIL variant that specifically binds to DR5 receptor, has recently been developed. We inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de1aa6de34f8c61e65e11b595f96203
https://doi.org/10.1158/1078-0432.c.6517572
https://doi.org/10.1158/1078-0432.c.6517572
Autor:
Steven de Jong, Ate G.J. van der Zee, Afshin Samali, Wim J. Quax, Robbert H. Cool, Go M. van Dam, Marjolijn N. Lub-de Hooge, Harry Hollema, Wytske Boersma-van Ek, Gert Jan Meersma, Devalingam Mahalingam, Elisabeth G.E. de Vries, Evelien W. Duiker
Supplementary Data from Enhanced Antitumor Efficacy of a DR5-Specific TRAIL Variant over Recombinant Human TRAIL in a Bioluminescent Ovarian Cancer Xenograft Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffe0a61c021d5d18b2c2caa625e976e
https://doi.org/10.1158/1078-0432.22440219
https://doi.org/10.1158/1078-0432.22440219
Autor:
Zhangping Xiao, Gerrit J. Poelarends, Wim J. Quax, Shanshan Song, Barbro N. Melgert, Frank J. Dekker, Robbert H. Cool, Deng Chen, Ronald van Merkerk, Petra E van der Wouden
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International ed. in English), 60(32), 17514-17521. WILEY-V C H VERLAG GMBH
Angewandte Chemie (International ed. in English), 60(32), 17514-17521. WILEY-V C H VERLAG GMBH
Macrophage migration inhibitory factor (MIF) is involved in protein‐protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF tauto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d51164a0c04702db2c8059a858ded3
https://doi.org/10.1002/anie.202101864
https://doi.org/10.1002/anie.202101864
Autor:
Zhangping, Xiao, Angelina, Osipyan, Shanshan, Song, Deng, Chen, Reinder A, Schut, Ronald, van Merkerk, Petra E, van der Wouden, Robbert H, Cool, Wim J, Quax, Barbro N, Melgert, Gerrit J, Poelarends, Frank J, Dekker
Publikováno v:
Journal of medicinal chemistry. 65(3)
The homologous cytokines macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT or MIF2) play key roles in cancers. Molecules binding to the MIF tautomerase active site interfere with its biological activity. In contrast, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f4a2932dbe26ff7dda594b028812747
https://pubmed.ncbi.nlm.nih.gov/35041425
https://pubmed.ncbi.nlm.nih.gov/35041425
Autor:
Zhangping Xiao, Frank J. Dekker, Shanshan Song, Robbert H. Cool, Fabian Mulder, Deng Chen, Barbro N. Melgert, Petra E van der Wouden, Gerrit J. Poelarends
Publikováno v:
Chemistry, 28(1):e202103030. Wiley-VCH Verlag GmbH & Co. KGaA
Macrophage migration inhibitory factor (MIF) and its homolog MIF2 (also known as D-dopachrome tautomerase or DDT) play key roles in cell growth and immune responses. MIF and MIF2 expression is dysregulated in cancers and neurodegenerative diseases. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c23129d373dc0f1773f9f19268eb5a
https://research.rug.nl/en/publications/4380903a-9d91-4662-8ef1-9828d3a7c6bd
https://research.rug.nl/en/publications/4380903a-9d91-4662-8ef1-9828d3a7c6bd
Autor:
Barbro N. Melgert, Xinhui Wu, Shanshan Song, Gerrit J. Poelarends, Martine J. Smit, Reinoud Gosens, Hidde J. Haisma, Habibie Habibie, Robbert H. Cool, Bin Liu, Corry-Anke Brandsma, Jelle van den Bor
Publikováno v:
European Respiratory Journal, 58. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6710c2ba33d29954a2319fdb80b489e7
https://doi.org/10.1183/13993003.congress-2021.OA2700
https://doi.org/10.1183/13993003.congress-2021.OA2700
Autor:
Gerrit J. Poelarends, Xinhui Wu, Martine J. Smit, Bin Liu, Jelle van den Bor, Reinoud Gosens, Shanshan Song, Barbro N. Melgert, Hidde J. Haisma, Habibie Habibie, Corry-Anke Brandsma, Robbert H. Cool
Publikováno v:
EBioMedicine
Song, S, Liu, B, Habibie, H, van den Bor, J, Smit, M J, Gosens, R, Wu, X, Brandsma, C-A, Cool, R H, Haisma, H J, Poelarends, G J & Melgert, B N 2021, ' D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling ', Ebiomedicine, vol. 68, 103412 . https://doi.org/10.1016/j.ebiom.2021.103412
EBioMedicine, Vol 68, Iss, Pp 103412-(2021)
EBioMedicine, 68:103412. ELSEVIER SCIENCE BV
Ebiomedicine, 68:103412. Elsevier BV
Song, S, Liu, B, Habibie, H, van den Bor, J, Smit, M J, Gosens, R, Wu, X, Brandsma, C-A, Cool, R H, Haisma, H J, Poelarends, G J & Melgert, B N 2021, ' D-dopachrome tautomerase contributes to lung epithelial repair via atypical chemokine receptor 3-dependent Akt signaling ', Ebiomedicine, vol. 68, 103412 . https://doi.org/10.1016/j.ebiom.2021.103412
EBioMedicine, Vol 68, Iss, Pp 103412-(2021)
EBioMedicine, 68:103412. ELSEVIER SCIENCE BV
Ebiomedicine, 68:103412. Elsevier BV
Background: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be0ae37e712e8db25b12d96f0abccbe
http://europepmc.org/articles/PMC8185224
http://europepmc.org/articles/PMC8185224
Autor:
Robbert H. Cool, Hidde J. Haisma, Xinhui Wu, J Van Den Bor, Shanshan Song, Corry-Anke Brandsma, Bin Liu, Gerrit J. Poelarends, Martine J. Smit, Reinoud Gosens, Barbro N. Melgert, Habibie Habibie
Publikováno v:
03.03 - Mechanisms of lung injury and repair.
Background: Emphysematous COPD is characterized by aberrant alveolar repair. Macrophage migration inhibitory factor (MIF) contributes to alveolar repair, but for its structural and functional homolog D-dopachrome tautomerase (DDT) this is unknown. MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b936f76dbfd4d53df6bde939fec80d9c
https://doi.org/10.1183/23120541.lsc-2021.85
https://doi.org/10.1183/23120541.lsc-2021.85