Zobrazeno 1 - 10 of 69 pro vyhledávání: '"H. Cooksley"'
1
Akademický článek
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2
Differential Expression of Immune Inhibitory Checkpoint Signatures on Antiviral and Inflammatory T Cell Populations in Chronic Hepatitis B
Autor: H. Cooksley, K. Katzarov, Roger Williams, Marieta Simonova, Shilpa Chokshi, Antonio Riva, S. Pavlova, Tanya Hadzhiolova-Lebeau
Publikováno v: Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 38(7)
Virus-specific T cells are critical in mediating the pathogenesis of hepatitis B virus (HBV) infection. Interferon gamma (IFNγ)-producing T cells are associated with resolution; in contrast, interleukin-17 (IL-17)-producing T cells are linked to exa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b0f6ec625e602b509b954c08510928
https://pubmed.ncbi.nlm.nih.gov/30016182
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3
Akademický článek
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4
Peg-interferon lambda Treatment induces robust innate and adaptive immunity in chronic hepatitis B Patients
Autor: Megan Wind-Rotolo, Michael Dao, Pei-Jer Chen, S. Phillips, Moon Seok Choi, Heng Chen Chu, Clive Woffendin, E. Cooney, H. Cooksley, Tanya Hadzhiolova-Lebeau, Shilpa Chokshi, Roger Williams, K. Katzarov, Robert J. de Knegt, Cheng Yuan Peng, Stefan Lueth, Ting-Tsung Chang, Stephan Zeuzem, Slava Plavova, Antonio Riva, Chang Wook Kim, S. Mistry, Heiner Wedemeyer, Marieta Simonova
Publikováno v: Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, 8:621. Frontiers Media S.A.
Frontiers in Immunology
IFN-lambda (IFNλ) is a member of the type III IFN family and is reported to possess anti-pathogen, anti-cancer, and immunomodulatory properties; however, there are limited data regarding its impact on host immune responses in vivo. We performed long
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a75ca4be11e3485a07c3fe7bf68ca49
https://doi.org/10.3389/fimmu.2017.00621
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5
Identification of Serum Cytokine Profiles Associated with HBeAg Seroconversion Following Antiviral Treatment Interruption
Autor: Roger Williams, H. Cooksley, Antonio Riva, Shilpa Chokshi, Anuj Gaggar, S. Phillips, Nikolai V. Naoumov
Publikováno v: Viral Immunology. 27:235-244
The major shortcoming of nucleos(t)ide analogue therapy for chronic hepatitis B (CHB) is the frequent requirement for indefinite therapy. Withdrawal of treatment can result in viral rebound with an alanine aminotransferase (ALT) flare leading to hepa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a7aee5b11733c2b222640bbaada483
https://doi.org/10.1089/vim.2014.0022
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6
Akademický článek
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7
Akademický článek
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8
Impact of Early Viral Kinetics on T-Cell Reactivity during Antiviral Therapy in Chronic Hepatitis B
Autor: Franck Rousseau, Emi Shudo, Ruy M. Ribeiro, H. Cooksley, Jane Anderson, Sharon R Lewin, Chee Kin Hui, George K. K. Lau, Elsa Mondou, Stephen Locarnini, Alan S. Perelson, Kimberly A. Powers, Jeff Sorbel, Scott Bowden, Nikolai V. Naoumov
Publikováno v: Scopus-Elsevier
Europe PubMed Central
BackgroundThe patterns of hepatitis B viral dynamics during different antiviral therapies and the associated changes in HBV-specific T-cell reactivity are not well defined.MethodsWe investigated the impact of early viral load decline on virus-specifi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19756c6a5e755b7d588ddf170017037
https://doi.org/10.1177/135965350701200513
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9
Hepatitis C Virus Persistence after Spontaneous or Treatment-Induced Resolution of Hepatitis C
Autor: H. Cooksley, Sonya A. MacParland, Nikolai V. Naoumov, Tomasz I. Michalak, Patricia M. Mulrooney, Tram N. Q. Pham
Publikováno v: Journal of Virology. 78:5867-5874
It is presumed that resolution of hepatitis C, as evidenced by normalization of liver function tests and disappearance of hepatitis C virus (HCV) RNA from serum, as determined by conventional laboratory assays, reflects virus eradication. In this stu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5cc7ee38273596c0a1458678141e681
https://doi.org/10.1128/jvi.78.11.5867-5874.2004
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10
Adhesion Molecule–dependent Mechanisms Regulate the Rate of Macrophage Clearance During the Resolution of Peritoneal Inflammation
Autor: Helen Cauldwell, Geoffrey J. Laurent, Stephen E. Bottoms, H. Cooksley, Anthony Shock, Steven E. Mutsaers, G Bellingan, Ping Xu, Christopher Haslett
Publikováno v: The Journal of Experimental Medicine
Macrophage clearance is essential for the resolution of inflammation. Much is known about how monocytes enter the inflammatory site but little is known about how resultant macro-phages are cleared. We have previously demonstrated that macrophage clea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e344d399592f515834c4fd184d3505d2
https://doi.org/10.1084/jem.20011794
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