Zobrazeno 1 - 5
of 5
pro vyhledávání: '"H. Christopher Meijndert"'
Autor:
Justin Chun, James R. Wright, Henry J. Duff, Paul W.M. Fedak, Daniel A. Muruve, H. Christopher Meijndert, Benjamin Gershkovich, Paul L. Beck, Nathan A. Bracey, Akosua Vilaysane
Publikováno v:
Journal of Biological Chemistry. 289:19571-19584
Nucleotide-binding domain and leucine-rich repeat containing PYD-3 (NLRP3) is a pattern recognition receptor that is implicated in the pathogenesis of inflammation and chronic diseases. Although much is known regarding the NLRP3 inflammasome that reg
Autor:
Holly E.M. Mewhort, H. Christopher Meijndert, Jeannine D. Turnbull, Janet M.C. Ngu, Paul W.M. Fedak
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 147(5):1650-1659
ObjectivesDysregulation of extracellular matrix (ECM) following myocardial infarction is a key contributor to myocardial fibrosis, chamber dilation, and progression to heart failure. Basic fibroblast growth factor is a potent inhibitor of fibrosis. W
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:1366-1376
Mitochondrial morphology is dynamic and controlled by coordinated fusion and fission pathways. The role of mitochondrial chaperones in mitochondrial morphological changes and pathology is currently unclear. Here we report that altered levels of DnaJA
Autor:
Sharon A. Clark, Akosua Vilaysane, Daniel A. Muruve, H. Christopher Meijndert, Virginie Pétrilli, Anne K. Zaiss, Pina Colarusso, Matthew J. Cotter, Jürg Tschopp, Robin M. Yates
Publikováno v:
The Journal of Immunology. 182:7058-7068
Adenovirus is a nonenveloped dsDNA virus that activates intracellular innate immune pathways. In vivo, adenovirus-immunized mice displayed an enhanced innate immune response and diminished virus-mediated gene delivery following challenge with the ade
Autor:
Kaiyu Wu, Craig N. Jenne, Stephen E. Malawista, Davide Salina, Paul Kubes, H. Christopher Meijndert, Björn Petri, Anne de Boisfleury Chevance, Kunyan Zhang, Brittney N V Scott, John Conly, Muhammad Asaduzzaman, Bryan G. Yipp, Keir Pittman, Lori Zbytnuik
Publikováno v:
Nature medicine. 18(9)
Gram-positive bacteria such as Staphylococcus aureus1–4 and Streptococcus pyogenes5 are highly invasive pathogens causing severe skin infections and sepsis in humans. Neutrophils are critical for host survival and NETs may represent a novel defense