Zobrazeno 1 - 10
of 10
pro vyhledávání: '"H. Chris Segar"'
Autor:
Syreeta L Tilghman, Melyssa R Bratton, H Chris Segar, Elizabeth C Martin, Lyndsay V Rhodes, Meng Li, John A McLachlan, Thomas E Wiese, Kenneth P Nephew, Matthew E Burow
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32754 (2012)
Several environmental agents termed "endocrine disrupting compounds" or EDCs have been reported to bind and activate the estrogen receptor-α (ER). The EDCs DDT and BPA are ubiquitously present in the environment, and DDT and BPA levels in human bloo
Externí odkaz:
https://doaj.org/article/98285dda656c419db9a34314ca93cba1
Autor:
Bridgette M. Collins-Burow, Lyndsay V. Rhodes, Matthew E. Burow, Elizabeth C. Martin, H. Chris Segar, Aaron Buechlein, Douglas B. Rusch, David F.B. Miller, Kenneth P. Nephew
Publikováno v:
Oncotarget
// Lyndsay V. Rhodes 4, * , Elizabeth C. Martin 1, * , H. Chris Segar 1 , David F. B. Miller 3 , Aaron Buechlein 5 , Douglas B. Rusch 5 , Kenneth P. Nephew 3 , Matthew E. Burow 1, 2 , Bridgette M. Collins-Burow 1 1 Department of Medicine, Section of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658b832ea6f4cadb92b9a146bd64956f
http://europepmc.org/articles/PMC4599295
http://europepmc.org/articles/PMC4599295
Autor:
Steven Elliott, Hope E. Burks, Diari Gilliam, Bridgette M. Collins-Burow, Muralidharan Anbalagan, Douglas B. Chrisey, H. Chris Segar, Van T. Hoang, Lyndsay V. Rhodes, Brian G. Rowan, Chandra R. Tate, Matthew E. Burow, F. Nell Pounder, Theresa B. Phamduy
Publikováno v:
Breast Cancer Research and Treatment. 145:593-604
Triple-negative breast cancer (TNBC) is a highly aggressive breast cancer subtype that lacks effective targeted therapies. The epithelial-to-mesenchymal transition (EMT) is a key contributor in the metastatic process. We previously showed the pan-dea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2cbbdb180909adf454d3c37ba8b31b3
https://doi.org/10.1007/s10549-014-2979-6
https://doi.org/10.1007/s10549-014-2979-6
Autor:
Matthew E. Burow, Kenneth P. Nephew, Thomas E. Wiese, Melyssa R. Bratton, Daniel E. Frigo, H. Chris Segar, John A. McLachlan
Publikováno v:
Environmental Health Perspectives
Background: The organochlorine dichlorodiphenyltrichloroethane (DDT), a known estrogen mimic and endocrine disruptor, has been linked to animal and human disorders. However, the detailed mechanism(s) by which DDT affects cellular physiology remains i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864af45d292f1b906d966a19085c4ed6
https://doi.org/10.1289/ehp.1104296
https://doi.org/10.1289/ehp.1104296
Autor:
Lyndsay V. Rhodes, Melyssa R. Bratton, Charles E. Wood, Yongkun Wei, Juan P. Fonseca, Barbara S. Beckman, Virgilio A. Salvo, Nicole F. Neel, Menghong Sun, Steven G. Elliott, Ann Richmond, Yun Zhu, Tammy Sobolik-Delmaire, Linda W. Horton, Kenneth P. Nephew, H. Chris Segar, Bridgette M. Collins-Burow, Snjezana Zaja-Milatovic, Rebecca A. Worthylake, Shannon E. Muir, Dihua Yu, Sarah P. Short, Syreeta L. Tilghman, Suzanne A. W. Fuqua, Paul Dent, Tyler J. Curiel, Mien Chie Hung, Matthew E. Burow, Scott Wadsworth
Publikováno v:
Cancer Research. 71:603-613
Estrogen independence and progression to a metastatic phenotype are hallmarks of therapeutic resistance and mortality in breast cancer patients. Metastasis has been associated with chemokine signaling through the SDF-1–CXCR4 axis. Thus, the develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79114ba6cb25c99ffbbbf3f0cf74ba0
https://doi.org/10.1158/0008-5472.can-10-3185
https://doi.org/10.1158/0008-5472.can-10-3185
Autor:
Stephen M. Boue, Steven Elliott, Matthew E. Burow, Melanie H. Howell, H. Chris Segar, John A. McLachlan, Thomas E. Wiese, Florastina Payton-Stewart, Carol H. Carter-Wientjes, K. Y. Williams, Barbara S. Beckman, Allen P. Miraflor, Betty Y. Shih, Thomas E. Cleveland, Syreeta L. Tilghman, M. Carla Zimmerman
Publikováno v:
Endocrinology. 150:2446-2453
The primary induced isoflavones in soybean, the glyceollins, have been shown to be potent estrogen antagonists in vitro and in vivo. The discovery of the glyceollins' ability to inhibit cancer cell proliferation has led to the analysis of estrogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994c63220a605f5e67c6416c5abc03bb
https://doi.org/10.1210/en.2008-1235
https://doi.org/10.1210/en.2008-1235
Autor:
Lyndsay V. Rhodes, F. Nell Pounder, Bridgette M. Collins-Burow, Jennifer L. Driver, H. Chris Segar, Chandra R. Tate, Matthew E. Burow
Publikováno v:
Breast Cancer Research : BCR
Introduction Of the more than one million global cases of breast cancer diagnosed each year, approximately fifteen percent are characterized as triple-negative, lacking the estrogen, progesterone, and Her2/neu receptors. Lack of effective therapies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50281546e357def180747c9093c1f286
https://doi.org/10.1186/bcr3192
https://doi.org/10.1186/bcr3192
Autor:
Meng Li, Melyssa R. Bratton, Lyndsay V. Rhodes, Matthew E. Burow, Thomas E. Wiese, Elizabeth C. Martin, H. Chris Segar, John A. McLachlan, Syreeta L. Tilghman, Kenneth P. Nephew
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32754 (2012)
PLoS ONE
PLoS ONE
Background Several environmental agents termed “endocrine disrupting compounds” or EDCs have been reported to bind and activate the estrogen receptor-α (ER). The EDCs DDT and BPA are ubiquitously present in the environment, and DDT and BPA level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b85392d59547c658d3996bb42cdc03b
http://europepmc.org/articles/PMC3293845?pdf=render
http://europepmc.org/articles/PMC3293845?pdf=render
Autor:
Bridgette M. Collins-Burow, Steven Elliott, Meng Li, Elizabeth C. Martin, Lyndsay V. Rhodes, Ashley M. Nitschke, Matthew E. Burow, Seung Yoon Nam, Jennifer L. Driver, H. Chris Segar, Kenneth P. Nephew
Publikováno v:
Oncology Reports.
The development of drug resistance represents a major complication in the effective treatment of breast cancer. Epigenetic therapy, through the use of histone deacetylase inhibitors (HDACi) or demethylation agents, is an emerging area of therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7233ea69ba7e439cdff153ea6e3eabcf
https://doi.org/10.3892/or.2011.1488
https://doi.org/10.3892/or.2011.1488
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