Zobrazeno 1 - 10
of 11
pro vyhledávání: '"H. C. T. Van Zaanen"'
Publikováno v:
The Netherlands journal of medicine. 78(1)
Rituximab is increasingly used in the treatment of CD20-positive B-cell-mediated disease. Prolonged use may cause B-cell dysfunction, dose-dependent T-cell dysfunction, and hypogammaglobulinaemia and result in severe non-neutropenic infections. We pr
Publikováno v:
The Netherlands journal of medicine. 73(5)
Autor:
L, Seghers, H C T, van Zaanen
Publikováno v:
The Netherlands journal of medicine. 72(3)
Autor:
Lucien A. Aarden, S. O. Warnaar, H. J. A. M. Rensink, J. Van Der Lelie, H. C. T. Van Zaanen, M. H. J. Van Oers, H. M. Lokhorst
Publikováno v:
British Journal of Haematology. 102:783-790
Interleukin 6 plays a key role in the pathogenesis of multiple myeloma (MM). Therefore we conducted a phase I dose-escalating study with chimaeric monoclonal anti-IL6 antibodies (cMab) in MM patients resistant to second-line chemotherapy. The cMab (C
Autor:
H. J. A. M. Rensink, H. C. T. Van Zaanen, M. H. J. Van Oers, S. O. Warnaar, H. M. Lokhorst, Lucien A. Aarden
Publikováno v:
Leukemia & lymphoma, 31(5-6), 551-558. Informa Healthcare
Interleukin-6 (IL6) plays a major role in the pathogenesis of multiple myeloma. In patients with monoclonal gammopathy serum levels of sIL6R have been found to be increased. The role of IL6 in the regulation of soluble receptors is still unclear. In
Autor:
Ed J. Kuijper, H. C. T. Van Zaanen, H. Van Der Lelie, B. L. M. Thomas, M. Mertens, A. E. G. K. Von Dem Borne, R. H. J. Van Oers, M. A. Leverstein-Van Hall
Publikováno v:
Scandinavian journal of infectious diseases, 27(6), 581-584. Informa Healthcare
We describe 3 patients with Corynebacterium jeikeium sepsis in neutropenic phase during treatment for acute myeloid leukaemia. Fever was the first symptom. All had a central venous catheter which was removed. Two patients developed subcutaneous nodul
Autor:
J. van der Lelie, H. C. T. van Zaanen
Publikováno v:
Cancer. 69:1710-1713
The case is reported of a patient with acute myeloid leukemia with severe right-sided congestive heart failure that responded to treatment with thiamine. Leukocytes cells contain relatively high concentrations of thiamine-dependent enzymes compared w
Publikováno v:
The Netherlands journal of medicine. 66(4)
We report a case of an adult, immunocompetent male with lymphadenopathy of both groins, para-aortal lymph nodes and multiple lesions in the spleen. A neoplasm was excluded by histology of the largest lymph node from the left groin. The diagnosis of c
Autor:
H. C. T. Van Zaanen, J. M. L. Stouthard, Lucien A. Aarden, Richard P. Koopmans, H. J. A. M. Rensink, M. H. J. Van Oers, S. O. Warnaar, H. M. Lokhorst
Publikováno v:
Journal of clinical investigation, 98(6), 1441-1448. The American Society for Clinical Investigation
In vitro as well as in vivo observations have shown that IL6 plays a key role in the pathogenesis of multiple myeloma. Therefore we started a phase I/II dose escalating study with chimeric monoclonal anti-IL6 antibodies (cMab) in multiple myeloma (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb8b5d78472ef7cc18731d75d9ad575c
https://pure.amc.nl/en/publications/endogenous-interleukin-6-production-in-multiple-myeloma-patients-treated-with-chimeric-monoclonal-antiil6-antibodies-indicates-the-existence-of-a-positive-feedback-loop(c3faf382-30ac-42b8-af6f-c91e87c28943).html
https://pure.amc.nl/en/publications/endogenous-interleukin-6-production-in-multiple-myeloma-patients-treated-with-chimeric-monoclonal-antiil6-antibodies-indicates-the-existence-of-a-positive-feedback-loop(c3faf382-30ac-42b8-af6f-c91e87c28943).html
Autor:
H. C. T. Van Zaanen, R. J. W. M. Vet, M. H. J. Van Oers, A. E. G. K. Von Dem Borne, C. M. De Jong
Publikováno v:
British journal of haematology. 91(1)
In this paper we describe a new, rapid and sensitive method to determine plasma cell isotype and clonality in bone marrow using flowcytometry. With the use of a new fixation and permeabilization reagent (Permeafix), which preserves cell structure and