Zobrazeno 1 - 10
of 34
pro vyhledávání: '"H. C. Stephen Chan"'
Autor:
Qi An, Na Li, Zhehui Zhao, Nuoqi Wang, Xueying Wang, Xiuying Yang, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du, H. C. Stephen Chan
Publikováno v:
ACS Omega, Vol 8, Iss 50, Pp 48028-48041 (2023)
Externí odkaz:
https://doaj.org/article/5e5d85721e1344268765d67fe1421010
Autor:
H. C. Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 274-282 (2020)
Externí odkaz:
https://doaj.org/article/bde47fbe587a4a428ff5afaf4a97398e
Publikováno v:
Molecules, Vol 27, Iss 5, p 1668 (2022)
Neural networks and deep learning have been successfully applied to tackle problems in drug discovery with increasing accuracy over time. There are still many challenges and opportunities to improve molecular property predictions with satisfactory ac
Externí odkaz:
https://doaj.org/article/5afb8fc66abf4098b927587e93b8e927
Autor:
Hua Yuan, Jinru Zhang, Yujuan Cai, Sheng Wu, Kui Yang, H. C. Stephen Chan, Wei Huang, Wen-Bing Jin, Yan Li, Yue Yin, Yasuhiro Igarashi, Shuguang Yuan, Jiahai Zhou, Gong-Li Tang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
GyrI-like proteins are small-molecule binding proteins that are widely distributed in prokaryotes and eukaryotes, with functions that are poorly characterized. Here, the authors identify GyrI-like proteins as cyclopropanoid cyclopropyl hydrolases tha
Externí odkaz:
https://doaj.org/article/266a1355c538408382157a4388d51a1c
Publikováno v:
Molecules, Vol 26, Iss 15, p 4625 (2021)
Protein–ligand interaction analysis is important for drug discovery and rational protein design. The existing online tools adopt only a single conformation of the complex structure for calculating and displaying the interactions, whereas both prote
Externí odkaz:
https://doaj.org/article/61bccf60148b46fdb84611f09764e26e
Publikováno v:
Journal of Chemical Information and Modeling. 62:3090-3095
Publikováno v:
Crystal Growth & Design.
Autor:
Paul Stainton, Elisa Nauha, Tudor Grecu, James F. McCabe, Tasnim Munshi, Ian Scowen, H. C. Stephen Chan, Sten Nilsson, Nicholas Blagden
Publikováno v:
Crystal Growth & Design. 22:1665-1679
This contribution presents a previously unreported example and comparative study of a binary crystalline adduct which exhibits a salt form in a 1:1 stoichiometry. Specifically, a new salt form of a novel 1:1 form of 3-(aminocarbonyl) pyridinium malon
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629734
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24d8089a11b73714cc78bf1b3abf702
https://doi.org/10.1007/978-1-0716-2974-1_10
https://doi.org/10.1007/978-1-0716-2974-1_10
Autor:
Shuguang Yuan, Pei-Hui Wang, Ximing Shao, H. C. Stephen Chan, Xueying Wang, Junlin Dong, Hongpei Li, Ke Liu, Wu Su, Meiqing Li, Hongchun Li, Hongchang Li, Rongfeng Zou, Cui Wenqiang
Publikováno v:
ACS Pharmacology & Translational Science
The outbreak of COVID-19 by the end of 2019 has posed serious health threats to humanity and jeopardized the global economy. However, no effective drugs are available to treat COVID-19 currently and there is a great demand to fight against it. Here,