Zobrazeno 1 - 10
of 235
pro vyhledávání: '"H. C. Pitot"'
Publikováno v:
Toxicological Sciences. 52:17-23
Studies of the multistage nature of hepatocarcinogenesis in the rat have led to the development of models having significant potential application to carcinogenesis in other tissues as well as other species. Whereas the initial and final stages of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63fbbd8635fc34b6480a8b880a8c260
https://doi.org/10.1093/toxsci/52.2.17
https://doi.org/10.1093/toxsci/52.2.17
Autor:
R M, O'Regan, A, Cisneros, G M, England, J I, MacGregor, H D, Muenzner, V J, Assikis, M M, Bilimoria, M, Piette, Y P, Dragan, H C, Pitot, R, Chatterton, V C, Jordan
Publikováno v:
JNCI Journal of the National Cancer Institute. 90:1552-1558
Background Tamoxifen has been shown to promote the growth of human endometrial tumors implanted in athymic mice, and it has been associated with a twofold to threefold increase in endometrial cancer. Toremifene, a chlorinated derivative of tamoxifen,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5113053f0e2b383e004dfd92452299a3
https://doi.org/10.1093/jnci/90.20.1552
https://doi.org/10.1093/jnci/90.20.1552
Autor:
Michael Camilleri, George M. Thomforde, James S. Scolapio, Joseph Rubin, Lee A. Forstrom, H C Pitot, S B Saslow, Duane Burton, Alan R. Zinsmeister
Publikováno v:
Gut. 42:628-634
Background—Carcinoid diarrhoea is associated with rapid small bowel and proximal colonic transit. Intravenous administration of a serotonin type 3 receptor (5HT3) antagonist restores postprandial colonic tone towards normal in carcinoid patients.Ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ca4229e78b6e6a14e0fcea1b9c3a4e
https://doi.org/10.1136/gut.42.5.628
https://doi.org/10.1136/gut.42.5.628
Publikováno v:
Toxicological Sciences. 43:129-138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::559b867c4134dc021e7ce78a6eb7b020
https://doi.org/10.1093/toxsci/43.2.129
https://doi.org/10.1093/toxsci/43.2.129
Publikováno v:
Journal of Biological Chemistry. 268:12530-12536
Expression of class 3 aldehyde dehydrogenase (ALDH-3) is constitutive or inducible, depending on the tissue. ALDH-3 induction occurs both during neoplastic development and after exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In order to stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60045e507b20ce18cbb62977fef4a782
https://doi.org/10.1016/s0021-9258(18)31421-2
https://doi.org/10.1016/s0021-9258(18)31421-2
Autor:
Larry K. Kvols, Patricia A. Pellikka, John A. Callahan, H C Pitot, Bijoy K. Khandheria, James B. Seward, Abdul J. Tajik
Publikováno v:
Circulation. 87:1188-1196
BACKGROUND The carcinoid syndrome is a rare cause of acquired valvular heart disease. Although the typical echocardiographic features of carcinoid heart disease are well recognized, this large series provides new information about unusual manifestati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e3e44a222fa7c9c8c34217e88b2315
https://doi.org/10.1161/01.cir.87.4.1188
https://doi.org/10.1161/01.cir.87.4.1188
Autor:
Y. P. DRAGAN, T. RIZVI, Y-H. XU, J. R. HULLY, N. BAWA, H. A. CAMPBELL, R. R. MARONPOT, H. C. PITOT
Publikováno v:
Toxicological Sciences. 16:525-547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375e53c1d6b3b645527ed472cfdefff3
https://doi.org/10.1093/toxsci/16.3.525
https://doi.org/10.1093/toxsci/16.3.525
Autor:
H C, Pitot
Publikováno v:
Developments in biologicals. 106
The basic animal model for neoplastic development used by regulatory agencies is the two-year chronic bioassay developed more than 30 years ago and based on the presumed mechanism of action of a few potential chemical carcinogens. Since that time, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a0fec6c06480bf5a3f56c239b5919ca
https://pubmed.ncbi.nlm.nih.gov/11761267
https://pubmed.ncbi.nlm.nih.gov/11761267
Autor:
H C, Pitot, R M, Goldberg
Publikováno v:
Oncology (Williston Park, N.Y.). 15(3 Suppl 5)
The current recommendation for adjuvant chemotherapy for patients with newly diagnosed stage III colon cancer involves 6 months of fluorouracil (5-FU) plus low- or high-dose leucovorin. In clinical trials performed throughout the world, several drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25e93244fbcaa56321f3c888813cdcc8
https://pubmed.ncbi.nlm.nih.gov/11301838
https://pubmed.ncbi.nlm.nih.gov/11301838