Zobrazeno 1 - 6
of 6
pro vyhledávání: '"H. C. Neijt"'
Publikováno v:
Behavioural pharmacology. 14(5-6)
The non-competitive NMDA receptor antagonist phencyclidine (PCP) is known to produce a discriminative stimulus in rats. The first aim of the present study was to investigate which NMDA receptor subtype(s) is involved in this effect of PCP. Rats were
Autor:
W P, Spooren, A, Vassout, H C, Neijt, R, Kuhn, F, Gasparini, S, Roux, R D, Porsolt, C, Gentsch
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 295(3)
Recently, selective and systemically active antagonists for the metabotropic glutamate 5 receptor (mGlu(5)) were discovered, and the most potent derivative was found to be MPEP (2-methyl-6-(phenylethynyl)pyridine). Given the high expression of mGlu(5
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(2)
Noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine are psychotomimetics and disrupt prepulse inhibition (PPI), a measure of sensorimotor gating that is deficient in schizophrenia. Systemically administered competiti
Publikováno v:
Behavioural Pharmacology. 16:S70-S71
Autor:
G. J. Blauw, P. van Brummelen, P. Vermeij, P. A. van Zvieten, H. W. C. M. Boddeke, H. N. Doods, P. A. van Zwieten, A. H. Bom, D. J. Duncker, P. D. Verdouw, P. R. Saxena, M. J. A. P. Daemen, H. T. M. Vervoort-Peters, H. H. W. Thijssen, D. Davidesko, H. D. Batink, H. D. Bangik, K. J. van Charldrop, S. F. de Boer, J. L. Slangen, J. van der Gugten, W. S. De Loos, B. Bohus, W. De Jong, D. De Wied, M. A. H. de Zwart, H. van der Goot, H. Timmerman, A. Garritsen, A. P. IJzerman, W. Soudijn, J. B. Heynis, H. W. G. M. Boddeke, B. J. A. Janssen, H. van Essen, H. A. J. Struyker Boudier, J. F. M. Smits, T. J. W. Jap, C. E. J. Ketelaars, J. Bruinvels, M. J. Krielaart, D. M. J. Veenstra, G. J. T. H. Stolze, L. M. L. le Noble, D. W. Slaaf, G. J. Tangelder, H. C. Neijt, I. J. te Duits, J. J. Plomp, H. P. M. Vijverberg, J. A. M. Raaijmakers, R. J. E. van den Eijnde, F. S. Radhakishun, J. C. Stoof, A. H. Mulder, D. H. G. Versteeg, J. M. van Ree, F. A. M. Redegeld, J. Noordhoek, J. M. H. M. Reul, J. A. D. M. Tonnaer, E. R. de Kloet, J. Riezebos, A. de Jonge, C. G. J. Sweep, V. M. Wiegant, F. Th. M. van Amsterdam, M. Haas, J. Zaagsma, R. G. M. van Amsterdam, F. Brouwer, K. J. van Charldorp, R. van de Straat, J. de Vries, N. P. E. Vermeulden, P. L. M. van Giersbergen, J van Harten, RRECM Zeegers, P van Brumnelen, DD Breimer, P. N. M. van Heiningen, E. J. van Hoogdalem, A. G. de Boer, D. D. Breimer, J. van Wijngaarden, H. Wesseling
Publikováno v:
Pharmaceutisch Weekblad. 8:270-278
Autor:
D, Hoyer, H C, Neijt
Publikováno v:
Molecular pharmacology. 33(3)
[3H]ICS 205-930 recognition sites were analyzed in membranes prepared from murine neuroblastoma N1E-115 cells. [3H]ICS 205-930 bound rapidly, reversibly, and stereoselectively to a homogeneous population of high affinity recognition sites: Bmax = 40