Zobrazeno 1 - 10
of 33
pro vyhledávání: '"H. C. McKirdy"'
Publikováno v:
British Journal of Surgery. 91:229-234
Background Nicotine has been shown to release nitric oxide from nerves in human sigmoid colon. This effect has been used to investigate the innervation and functional relationship of the longitudinal and circular muscle layers. Methods Strips of long
Publikováno v:
Digestive Diseases and Sciences. 39:2229-2234
Strips from human gallbladder removed at surgery were exposed to cholecystokinin octopeptide CCK-OP 15 nM and were subjected to electrical field stimulation (EFS) in vitro using parameters for selective stimulation of nerves (5- to 10-sec trains of 0
Publikováno v:
ANZ Journal of Surgery. 64:322-326
A prospective study of anorectal physiological testing in 26 patients with obstructed defecation and 20 patients with faecal incontinence was performed. There were overlaps in individual test parameters between the two groups of patients. However, pa
Publikováno v:
Diseases of the Esophagus. 14:54-56
Assessment of the effect of balloon dilation of the lower esophageal sphincter in achalasia currently relies on symptom scores, radiologic studies, or manometry. We have used vector volume analysis which constructs a three-dimensional (3D) pressure p
Autor:
J T, Green, C, Richardson, R W, Marshall, J, Rhodes, H C, McKirdy, G A, Thomas, G T, Williams
Publikováno v:
Alimentary pharmacologytherapeutics. 14(11)
Ulcerative colitis is a condition of nonsmokers in which nicotine is of therapeutic benefit.To examine the in vitro effect of nicotine on colonic smooth muscle activity and the role of nitric oxide (NO) as a mediator.Nicotine, 1-10 microM, was admini
Publikováno v:
Gut. 35(3)
Non-adrenergic non-cholinergic (NANC) inhibitory nerves have been described in all regions of the gastrointestinal tract, but have not been shown previously in the human gall bladder. Electrical field stimulation was used in the presence of various a
Publikováno v:
Digestion. 54(4)
Circular muscle strips from the human ileocaecal junction developed myogenic tone (sustained resting tension) in vitro and showed an obvious component of relaxation in response to electrical field stimulation. These features are considered typical of
Publikováno v:
Experimental physiology. 77(3)
Electrical field stimulation of circular muscle strips from human lower oesophageal sphincter reveals a predominant relaxation response. This relaxation is non-adrenergic non-cholinergic (NANC). The nitric oxide synthesis-blocking agent N omega-nitro
Autor:
H. C. McKirdy
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 295:G209-G209
to the editor: In their recent paper, Cong et al. ([1][1]) argue that nitric oxide (NO) does not play a role in the relaxation of gallbladder muscle strips since a nitric oxide synthase inhibitor (NOSI) does not change gallbladder tonic contraction o
Publikováno v:
Diseases of the Colon & Rectum. 38:669-670