Výsledky vyhledávání - "H. C. J. Van Rooij"

The mouse androgen receptor. Functional analysis of the protein and characterization of the gene

Autor: H. C. J. Van Rooij, N. J. De Both, A King, P.W. Faber, Jan Trapman, Albert O. Brinkmann

Publikováno v: Biochemical Journal. 278:269-278

Screening a mouse genomic DNA library with human androgen-receptor (hAR) cDNA probes resulted in the isolation and characterization of eight genomic fragments that contain the eight exons of the mouse androgen-receptor (mAR) gene. On the basis of sim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f9a3389a6479609ee2287d4692d147
https://doi.org/10.1042/bj2780269

Zobrazit plný text záznamu

Characterization of the human androgen receptor transcription unit

Autor: J. A. Grootegoed, Albert O. Brinkmann, H. C. J. Van Rooij, Jan Trapman, H. A. G. M. Van Der Korput, Willy M. Baarends, P.W. Faber

Publikováno v: Journal of Biological Chemistry. 266:10743-10749

A full length human androgen receptor (hAR) cDNA was constructed from cDNA and genomic clones. Structurally the 10.6-kilobase (kb) hAR cDNA consists of a long 5'-untranslated region (5'-UTR, 1.1 kb), a previously described open reading frame (ORF, 2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::527689fccac2c069c499cbb3d4782d93
https://doi.org/10.1016/s0021-9258(18)99080-0

Zobrazit plný text záznamu

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

Autor: Eric Claassen, Jan Trapman, Eppo Mulder, Cor A. Berrevoets, H. C. J. Van Rooij, Jos Veldscholte, C. Ris-Stalpers, Albert O. Brinkmann, George G. J. M. Kuiper, Guido Jenster

Publikováno v: Biochemical and biophysical research communications, 173(2), 534-540. Academic Press Inc.

LNCaP prostate tumor cells contain an abnormal androgen receptor system. Progestagens, estradiol and anti-androgens can compete with androgens for binding to the androgen receptor and can stimulate both cell growth and excretion of prostate specific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17378883e474f7689a8e8c0a6a5fccba
https://doi.org/10.1016/s0006-291x(05)80067-1

Zobrazit plný text záznamu

Substitution of aspartic acid-686 by histidine or asparagine in the human androgen receptor leads to a functionally inactive protein with altered hormone-binding characteristics

Autor: L Pinsky, Morris Kaufman, Sai Tj, Jan Trapman, H.U. Schweikert, Albert O. Brinkmann, Gabriela Romalo, Robert L. Rosenfield, George G. J. M. Kuiper, Shutsung Liao, Mark Trifiro, Guido Jenster, H. C. J. Van Rooij, C. Ris-Stalpers

Publikováno v: Molecular endocrinology (Baltimore, Md.), 5(10), 1562-1569. The Endocrine Society

We have identified two different single nucleotide alterations in codon 686 (GAC; aspartic acid) in exon 4 of the human androgen receptor gene in three unrelated families with the complete form of androgen insensitivity. One mutation (G----C) results

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e816b26479461d5d2d44fd90f1e0b6c3
https://pubmed.ncbi.nlm.nih.gov/1775137

Zobrazit plný text záznamu

Androgen receptor abnormalities

Autor: Leonard Pinsky, Albert O. Brinkmann, Jan Trapman, C. Ris-Stalpers, George G. J. M. Kuiper, Mark Trifiro, Gabriela Romalo, H.U. Schweikert, Eppo Mulder, H. C. J. Van Rooij

Publikováno v: Journal of steroid biochemistry and molecular biology, 40(1-3), 349-352. Elsevier Limited

The human androgen receptor is a member of the superfamily of steroid hormone receptors. Proper functioning of this protein is a prerequisite for normal male sexual differentiation and development. The cloning of the human androgen receptor cDNA and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9972931f14ae90f6dd635afaa79daabc
https://pubmed.ncbi.nlm.nih.gov/1958538

Zobrazit plný text záznamu

Aberrant splicing of androgen receptor mRNA results in synthesis of a nonfunctional receptor protein in a patient with androgen insensitivity

Autor: C. Ris-Stalpers, M. B. Hodgins, Albert O. Brinkmann, H. C. J. Van Rooij, H. U. Schweikert, N.D. Zegers, George G. J. M. Kuiper, H J Degenhart, P.W. Faber, Jan Trapman

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 87(20), 7866-7870. National Academy of Sciences

Androgen insensitivity is a disorder in which the correct androgen response in an androgen target cell is impaired. The clinical symptoms of this X chromosome-linked syndrome are presumed to be caused by mutations in the androgen receptor gene. We re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0298924be5870b2761b889b394b302
https://pure.amc.nl/en/publications/aberrant-splicing-of-androgen-receptor-mrna-results-in-synthesis-of-a-nonfunctional-receptor-protein-in-a-patient-with-androgen-insensitivity(3eab41f8-7b00-4884-bfb6-6422b2c9895b).html

Zobrazit plný text záznamu

Hormonal control of glycogenolysis in parenchymal liver cells by Kupffer and endothelial liver cells

Autor: Johan F. Koster, H. C. J. Van Rooij, Jan A. A. M. Kamps, J Kuiper, T.J.C. van Berkel, Eric Casteleijn

Publikováno v: Journal of Biological Chemistry. 263:2699-2703

Conditioned media of isolated Kupffer and endothelial liver cells were added to incubations of parenchymal liver cells, in order to test whether secretory products of Kupffer and endothelial liver cells could influence parenchymal liver cell metaboli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::16aaa25428e4ec1506dd00feb91a3764
https://doi.org/10.1016/s0021-9258(18)69124-0

Zobrazit plný text záznamu

Enhancement and suppression of DTH reactivity to Rauscher murine leukaemia virus induced tumour cell lines

Autor: A. C. Knulst, H. C. J. Van Rooij, C. Bazuin, D. Berends, N. J. De Both, R. Benner

Publikováno v: British Journal of Cancer

Delayed-type hypersensitivity (DTH) to Rauscher murine leukaemia virus (R-MuLV) encoded or induced determinants was induced in mice by three syngeneic R-MuLV-induced tumour cell lines, i.e. a myeloid tumour, RMB-1, an erythroid tumour, RED-1, and a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8dee0963d5a4aeabea7b634c1ebbaa4
https://doi.org/10.1038/bjc.1989.284

Zobrazit plný text záznamu

Prostaglandin D2 mediates the stimulation of glycogenolysis in the liver by phorbol ester

Autor: J. F. Koster, Johan Kuiper, E. Casteleijn, Jan A. A. M. Kamps, H. C. J. Van Rooij, T. J. C. Van Berkel

Publikováno v: Biochemical Journal. 250:77-80

The tumour-promoting phorbol ester, phorbol 12-myristate 13-acetate (PMA), when added to the perfused liver, stimulates glycogenolysis 2-fold. This stimulation is not seen when aspirin is present in the perfusion medium. In isolated parenchymal liver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2494844e01ed0b02bc855af625f1088e
https://doi.org/10.1042/bj2500077

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání