Zobrazeno 1 - 10
of 45
pro vyhledávání: '"H. C. Gonick"'
Autor:
N D, Vaziri, H C, Gonick
Publikováno v:
The Indian journal of medical research. 128(4)
Several epidemiological and clinical studies have found a link between chronic lead exposure and elevated blood pressure. In addition, a few population studies have shown possible connection between lead exposure and other cardiovascular disorders in
Publikováno v:
American journal of hypertension. 12(4 Pt 1)
It has been demonstrated that human plasma contains a low molecular weight sodium-potassium-stimulated adenosine triphosphatase (Na-K-ATPase) inhibitor, which can be dissociated from a circulating protein with a molecular weight of approximately 12,0
Publikováno v:
Environmental research. 76(2)
Administration of 100 ppm lead acetate daily for 3 months caused hypertension in Sprague-Dawley rats, with reversal by treatment with 2,3-dimercaptosuccinic acid (DMSA) (0.5% for 2 weeks). Animals from each group were infused sequentially in 30-min i
Publikováno v:
Mineral and electrolyte metabolism. 23(2)
The skeleton, the major site for Pb accumulation, is responsible for the largest fraction of the total body burden, but long-term effects of low-level exposure in adults remain unclear. In this study rats were exposed to low (0.01%; 100 ppm, LoPb) or
Autor:
Ralph E. Purdy, Elmar W. J. Weiler, L F Saldanha, H C Gonick, F Khalil-Manesh, Bruce A. Prins
Publikováno v:
Journal of the American Society of Nephrology : JASN. 7(3)
Inhibitors of sodium-potassium-activated adenosine triphosphatase (Na-K-ATPase) have been implicated in the pathogenesis of hypertension. In the study presented here, an attempt was made to determine whether differences in the plasma levels and the r
Publikováno v:
Journal of trace elements and electrolytes in health and disease. 8(1)
Adverse effects on hematopoiesis and renal function have been reported in both animals and humans exposed to high doses of lead for a protracted period of time, but little is known about the interrelationship between these two target organ systems. T
Publikováno v:
Environmental research. 58(1)
Male Sprague-Dawley rats were exposed to high-dose (0.5%) lead acetate for periods ranging from 1 to 9 months; then lead exposure was discontinued, and animals were sacrificed after 12 months. Controls were pair-fed. Two additional groups of low-dose
Publikováno v:
Clinical Science. 53:329-334
1. Serum was collected from normal rats and from rats volume-expanded with isotonic sodium chloride solution. 2. The serum was fractionated by gel filtration on Sephadex G-25 and each fraction was tested for inhibitory activity against sodium—potas
Autor:
H C Gonick, L F Saldanha
Publikováno v:
Journal of Clinical Investigation. 56:247-255
Homogenates of kidneys from hydropenic and volume-expanded rats were subjected to gel filtration with Sephadex G-25. A fraction of the eluate coincident with the fourth UV peak was injected into the aorta of rats with one kidney excluded. A fraction
Publikováno v:
Circulation Research. 38:250-255
Boiled homogenates of kidneys from volume-expanded and hydropenic rats were subjected to column chromatography. The fraction eluting within the range of partition coefficients (Kav) 0.76-0.89 (fraction III) was lyophilized and the effects of this sem