Zobrazeno 1 - 10
of 275
pro vyhledávání: '"H. C. Birnboim"'
Autor:
H. C. Birnboim, Olle M. de Bruin
Publikováno v:
BMC Microbiology
Background DNA-based testing is becoming the preferred method both for identifying microorganisms and for characterizing microbial communities. However, no single DNA extraction method exists that is suitable for all types of microorganisms because b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cef8f31f6a36fc67399d58f5498a961
https://doi.org/10.1186/s12866-016-0815-3
https://doi.org/10.1186/s12866-016-0815-3
Publikováno v:
British Journal of Cancer
Thymidylate synthase (TS) is the enzyme that catalyses the last step in de novo thymidylate synthesis. It is of interest clinically because it is an effective target for drugs such as 5-fluorouracil, often used in combination therapy. Despite a numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e89bee49ecd7a29f2885ccbcc17f0f3b
http://europepmc.org/articles/PMC2360461
http://europepmc.org/articles/PMC2360461
Autor:
H C Birnboim, Randy T. Cowling
Publikováno v:
Journal of Leukocyte Biology. 67:240-248
Stimulation of human peripheral blood granulocytes with the proinflammatory cytokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), increases incorporation of [3H]uridine into RNA. We investigated the nature of the RNA synthesized under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67b79404a4df82113d33620be59550d0
https://doi.org/10.1002/jlb.67.2.240
https://doi.org/10.1002/jlb.67.2.240
Publikováno v:
Journal of Histochemistry & Cytochemistry. 47:1563-1573
Measurement of thymidylate synthase (hTS) using immunohistochemical techniques has been reported in several clinical studies. However, its value as a prognostic indicator is still not clear. To pursue this, we have developed a new rabbit polyclonal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9421844884d686dc13314f365279da97
https://doi.org/10.1177/002215549904701208
https://doi.org/10.1177/002215549904701208
Publikováno v:
Arthritis & Rheumatism. 41:1772-1782
Objective To investigate the frequency and characteristics of hprt- mutant T lymphocytes in the peripheral blood and synovium of rheumatoid arthritis (RA) patients compared with controls, and to correlate these findings with disease parameters. Metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9774638daa72cbe0e307c869d59ac982
https://doi.org/10.1002/1529-0131(199810)41:10<1772::aid-art9>3.0.co
https://doi.org/10.1002/1529-0131(199810)41:10<1772::aid-art9>3.0.co
Autor:
H. C. Birnboim, Steffany A. L. Bennett
Publikováno v:
Molecular Carcinogenesis. 20:366-375
Chronic inflammation is a recognized risk factor for human cancer, but the causal mechanisms are poorly understood. We previously demonstrated that platelet activating factor (PAF) can induce alterations in the in vitro growth properties of primary r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44c687208e849f1ee07bac73be5c1807
https://doi.org/10.1002/(sici)1098-2744(199712)20:4<366::aid-mc6>3.0.co
https://doi.org/10.1002/(sici)1098-2744(199712)20:4<366::aid-mc6>3.0.co
Autor:
J K Sandhu, H C Birnboim
Publikováno v:
Journal of Cellular Biochemistry. 66:219-228
Phorbol ester treatment of granulocytes triggers release of superoxide (O2.-) and a concomitant burst of DNA strand breaks. The relationship between the amount of O2.- and the number of DNA breaks has not previously been explored. To quantify the rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10fd52fda762b294c298042046aba731
https://doi.org/10.1002/(sici)1097-4644(19970801)66:2<219::aid-jcb9>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19970801)66:2<219::aid-jcb9>3.0.co
Publikováno v:
Journal of Virological Methods. 50:245-255
Although a useful and important method of gene transfer, retroviral vectors can be genetically unstable. In the course of experiments using DOEJS, a retroviral vector able to confer expression of a H-ras oncogene and a neomycin resistance gene (neo)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0267cb6162c4a8713c1542c817983da
https://doi.org/10.1016/0166-0934(94)90181-3
https://doi.org/10.1016/0166-0934(94)90181-3
Autor:
H C Birnboim, Randy T. Cowling
Publikováno v:
Journal of Biological Chemistry. 269:9480-9485
When human peripheral blood granulocytes were metabolically labeled at 37 degrees C with [32P]orthophosphate, inorganic polyphosphates became preferentially radiolabeled. Incorporation of radiolabel into the polymer appeared to be ATP-independent. [3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0812f40deb2f5f0cab9be170f6356771
https://doi.org/10.1016/s0021-9258(17)36906-5
https://doi.org/10.1016/s0021-9258(17)36906-5
Publikováno v:
Free Radical Research. 20:113-117
8-Hydroxydeoxyguanosine (8-OHdG) is now widely used as a sensitive marker of oxidative damage to DNA. When human granulocytes are stimulated with TPA, they release a large quantity of reactive oxygen species (superoxide, hydrogen peroxide) which migh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0dd669d039b056d505a034a0c421c3
https://doi.org/10.3109/10715769409147508
https://doi.org/10.3109/10715769409147508