Zobrazeno 1 - 10
of 944
pro vyhledávání: '"H. Burke"'
Autor:
T. J. M. Wallis, E. Heiden, J. Horno, B. Welham, H. Burke, A. Freeman, L. Dexter, A. Fazleen, A. Kong, C. McQuitty, M. Watson, S. Poole, N. J. Brendish, T. W. Clark, T. M. A. Wilkinson, M. G. Jones, B. G. Marshall
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background The long-term consequences of COVID-19 remain unclear. There is concern a proportion of patients will progress to develop pulmonary fibrosis. We aimed to assess the temporal change in CXR infiltrates in a cohort of patients follow
Externí odkaz:
https://doaj.org/article/f6a3be9c15764e13b239b4f1f1405b17
Autor:
H. Burke, A. Freeman, D. C. Cellura, B. L. Stuart, N. J. Brendish, S. Poole, F. Borca, H. T. T. Phan, N. Sheard, S. Williams, C. M. Spalluto, K. J. Staples, T. W. Clark, T. M. A. Wilkinson, on behalf of the REACT COVID investigators
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-9 (2020)
Abstract Background The COVID-19 pandemic has led to more than 760,000 deaths worldwide (correct as of 16th August 2020). Studies suggest a hyperinflammatory response is a major cause of disease severity and death. Identitfying COVID-19 patients with
Externí odkaz:
https://doaj.org/article/b0917f231c514b73ab849e7bead217ad
Autor:
Brian J. Thomas, Caitlyn Guldenpfennig, Yue Guan, Calvin Winkler, Margaret Beecher, Michaela Beedy, Ashley F. Berendzen, Lixin Ma, Mark A. Daniels, Donald H. Burke, David Porciani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102046- (2023)
A significant fraction of non-small cell lung cancer (NSCLC) cases are due to oncogenic mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR). Anti-EGFR antibodies have shown limited clinical benefit for NSCLC, wherea
Externí odkaz:
https://doaj.org/article/a21d444d7c774c959bf15916e11144f4
Autor:
Khalid K. Alam, Jonathan L. Chang, Margaret J. Lange, Phuong D.M. Nguyen, Andrew W. Sawyer, Donald H. Burke
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 605-619 (2018)
Aptamer selections often yield distinct subpopulations, each with unique phenotypes that can be leveraged for specialized applications. Although most selections aim to attain ever higher specificity, we sought to identify aptamers that recognize incr
Externí odkaz:
https://doaj.org/article/21625fee9d3f4cffbf55bb529e64a415
Autor:
John S. Samuelian, Thomas J. Gremminger, Zhenwei Song, Raghav R. Poudyal, Jun Li, Yuanzhe Zhou, Seth A. Staller, Johan A. Carballo, Manami Roychowdhury-Saha, Shi-Jie Chen, Donald H. Burke, Xiao Heng, Dana A. Baum
Publikováno v:
Nature Chemical Biology. 18:1263-1269
The discovery of ribozymes has inspired exploration of RNA’s potential to serve as primordial catalysts in a hypothesized RNA world. Modern oxidoreductase enzymes employ differential binding between reduced and oxidized forms of redox cofactors to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ffd8a9f69d1a86aafe6c5f87d62b68
https://doi.org/10.1038/s41589-022-01121-4
https://doi.org/10.1038/s41589-022-01121-4
Autor:
Paul J. Griffin, Bronte J. Charette, John H. Burke, Josh Vura-Weis, Richard D. Schaller, David J. Gosztola, Lisa Olshansky
Publikováno v:
Journal of the American Chemical Society. 144:12116-12126
The continued development of solar energy as a renewable resource necessitates new approaches to sustaining photodriven charge separation (CS). We present a bioinspired approach in which photoinduced conformational rearrangements at a ligand are tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90b9d48ccac8c80ca5b5a6dfc079e8d6
https://doi.org/10.1021/jacs.2c02580
https://doi.org/10.1021/jacs.2c02580
Autor:
Kamal Singh, Fabio Gallazzi, Kyle J. Hill, Donald H. Burke, Margaret J. Lange, Thomas P. Quinn, Ujjwal Neogi, Anders Sönnerborg
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Recently reported HIV-1 capsid (CA) inhibitors GS-CA1 and GS-6207 (an analog of GS-CA1) are first-in-class compounds with long-acting potential. Reportedly, both compounds have greater potency than currently approved anti-HIV drugs. Due to the limite
Externí odkaz:
https://doaj.org/article/ecd49d6f831444949e23e5d46496fd9a
Autor:
Mathew D. Sorensen, Jonathan D. Harper, Michael S. Borofsky, Tariq A. Hameed, Kimberly J. Smoot, Barbara H. Burke, Branda J. Levchak, James C. Williams, Ziyue Liu, Michael R. Bailey, James E. Lingeman
Publikováno v:
Journal of Urology. 209
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9104b0f12e654b3fc99df287808b3bb5
https://doi.org/10.1097/ju.0000000000003248.11
https://doi.org/10.1097/ju.0000000000003248.11
Autor:
Adrienne M. Dorrance, Ramiro Garzon, Clara D. Bloomfield, Xiaoli Zhang, Mikhail M. Dikov, Aharon G. Freud, Ansel P. Nalin, Zachary J. Brannan, Allison E. Walker, Allison LaRocco, Katiri Snyder, Nina C. Zitzer, Dimitrios Papaioannou, Parvathi Ranganathan, Matthew H. Burke, Changxian Shen, Malith Karunasiri, Aparna Pathmanathan, Marius Bill
Purpose:EGF-like domain 7 (EGFL7) is a secreted protein and recently has been shown to play an important role in acute myeloid leukemia (AML); however, the underlying mechanism by which EGFL7 promotes leukemogenesis is largely unknown.Experimental De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a28f5404bd945ccc838b74dcdb20b3
https://doi.org/10.1158/1078-0432.c.6529856.v1
https://doi.org/10.1158/1078-0432.c.6529856.v1
Autor:
Adrienne M. Dorrance, Ramiro Garzon, Clara D. Bloomfield, Xiaoli Zhang, Mikhail M. Dikov, Aharon G. Freud, Ansel P. Nalin, Zachary J. Brannan, Allison E. Walker, Allison LaRocco, Katiri Snyder, Nina C. Zitzer, Dimitrios Papaioannou, Parvathi Ranganathan, Matthew H. Burke, Changxian Shen, Malith Karunasiri, Aparna Pathmanathan, Marius Bill
Additional Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e06d19c7156925a911b941f23ae234
https://doi.org/10.1158/1078-0432.22478123.v1
https://doi.org/10.1158/1078-0432.22478123.v1