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Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial

Autor: M B Manning, D A Streja, C Keller, C H Chung, P L Beckett, A Özdemir, Y M Cho, I Colin, L J Aronne, Erik Christiansen, Markus Laimer, L Van Gaal, S N Lederman, T M O'Connor, L J Klaff, S Aronoff, S H Baik, A V Murray, Signe O R Wallenstein, N A Godbole, H O Høivik, Dilek Gogas Yavuz, A Golay, G T'Sjoen, B Delgado, I N El Ebrashy, E S Kang, C Wium, Bruce W. Bode, Ramazan Sari, B A Palchick, J Geohas, P R Nicol, M Winnie, N Aladağ, E W Braun, C Vercammen, S A Shelbaya, K Sivalingam, S Gorban de Lapertosa, E Riffer, F G Eliaschewitz, J B Buse, B Schultes, C H Sorli, K-W Lee, Mark Warren, T Pieber, S Stäuble, R Prager, A Mertens, A A Arif, D C Eagerton, A Scheen, I J Kim, J A Seo, S Ong, E Ataoglu, John B. Buse, D Berker, A White, F Helland, J C LaRocque, Young Min Cho, Christin L. Hertz, E M Palace, L H S Canani, M P Finneran, S H A Khalil, H L Gulseth, D Weiss, J Condit, E Fließer-Görzer, L Rista, S Akın, M H M F El Hefnawy, N H Kim, C Issa, S Bilz, H Bays, S Fischli, V Preumont, J Pereles-Ortiz, B Bode, E J Morawski, Aytekin Oguz, J Cooper, Tamer Tetiker, Ann Mertens, G Rudofsky, Thomas R. Pieber, W R Litchfield, J L Gross, D L Weinstein

Publikováno v: The lancet. Diabetesendocrinology. 7(7)

BACKGROUND: Oral semaglutide is the first oral formulation of a glucagon-like peptide-1 (GLP-1) receptor agonist developed for the treatment of type 2 diabetes. We aimed to compare the efficacy and safety of flexible dose adjustments of oral semaglut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e132376f3cbf48c52376523aef27e59f
https://pubmed.ncbi.nlm.nih.gov/31320282

Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial

Autor: Erin A Bohula, Benjamin M Scirica, Silvio E Inzucchi, Darren K McGuire, Anthony C Keech, Steven R Smith, Estella Kanevsky, Sabina A Murphy, Lawrence A Leiter, Jamie P Dwyer, Ramon Corbalan, Christian Hamm, Lee Kaplan, Jose Carlos Nicolau, Ton Oude Ophuis, Kausik K Ray, Mikhail Ruda, Jindrich Spinar, Tushar Patel, Wenfeng Miao, Carlos Perdomo, Bruce Francis, Shobha Dhadda, Marc P Bonaca, Christian T Ruff, Marc S Sabatine, Stephen D Wiviott, Silvio Inzucchi, Anthony Keech, Andrew Satlin, Conville Brown, Andrzej Budaj, Jamie Dwyer, Armando Garcia-Castillo, Milan Gupta, Kauski Ray, Neil Weissman, Harvey D White, J Amerena, M Arstall, D Colquhoun, R Jayasinghe, A Lee, R Lehman, R Moses, J Proietto, P Purnell, J Waites, P Blombery, D Cross, M Worthley, M d'Emden, J Selvanayagam, RE Oqueli, A Whelan, P Garrahy, F de Looze, D Ninio, J Horowitz, M William, M Suranyi, G Wittert, M Le May, AS Pandey, S Vizel, R Labonte, Y Beaudry, C Fortin, A Bell, S Kouz, É St-Amour, I Bata, F St Maurice, R Chehayeb, C Constance, G Wong, A Hess, J Liutkus, P Poirier, I Teitelbaum, J Berlingieri, J Cha, M Hartleib, M Heffernan, D Twum-Barima, V Pandith, R Aronson, R Goldenberg, B Ajala, A Jain, S Ross, H Bajaj, H Khandwala, Z Yared, N Gupta, J Bédard, S Wharton, F Blouin, D Savard, D Shukla, J Cobos, G Godoy, L Perez, C Pincetti, V Saavedra Guajardo, P Varleta, C Conejeros, F Lanas, E Bayram Llamas, E Cardona Muñoz, R Garcia, J Garza Ruiz, G Llamas Esperon, E Lopez Rosas, G Melendez Mier, G Ramos, H Hart, D Scott, I Ternouth, J Benatar, J Elliott, R Cutfield, P Manning, M Williams, K Ferrier, R Scott, S Wilson, R Leikis, BK Nirmalaraj, E Krzyżagórska, P Miękus, M Bronisz, E Mirek-Bryniarska, K Łanda, A Stasiewski, T Żechowicz, D Zytkiewicz-Jaruga, J Korecki, M Ogórek, L Pawłowicz, M Piepiorka, J Skierkowska, A Stankiewicz, E Szyprowska, R Witek, A Bochenek, P Kończakowski, Ł Wojnowski, M Wujkowski, K Cymerman, R Korzeniak, P Mąder, B Mikłaszewicz, P Stachlewski, A Goch, W Pomiećko, M Skórski, L Romanowski, K Jusiak, E Laskowska-Derlaga, R Bijata-Bronisz, J Kaźmierczak, R Goldberg, D Henderson, E Korban, K Rohr, E Claxton, R Weiss, D Angiolillo, F Boccalandro, K Chu, E Thorn, P Randhawa, N Singh, G Bittar, T Guarnieri, S Saeed, S Sharma, M Shepard, W French, P Desai, R Bernstein, W Rogers, R Singal, R Schneider, J Shanes, S Ong, J Condit, S Donahoe, D Brill, D Einhorn, R Ebrahimi, A Labroo, R Graf, J Scott, J Hoekstra, P Jetty, G Luckasen, P O'Donnell, W Gonte, D Pomposini, M Quadrel, M Koren, D Schlager, E Schramm, D Singal, S Lupovitch, A Soni, P Seigel, J Roberts, J Soufer, S Reza, E Quinlan, T Moretto, B First, M Khan, S Chilka, H Colfer, A Teklinski, K Wallace-Wilding, H Ellison, D Muse, S Aronoff, A Higgins, S Patel, V Elinoff, A Karim, V Awasty, R Chuang, H Roseman, P Dugano-Daphnis, M Albert, K Sheikh, H Bays, S Kaster, M Goldstein, D Rubino, G Calatayud, H Snyder, T Williams, K Hershon, M Hagan, S Isserman, B Kahn, J Anderson, MP Gimness, A Raisinghani, M Christina, M Raikhel, E Gillespie, E Portnay, M Heiman, M Qureshi, J Lee, R Blonder, F Cucher, G Miller, D Kotlaba, G Cornett, J Beavins, C Augenbraun, S Reinhardt, A Bartkowiak, A Salacata, T Blevins, S Benjamin, J Diener, W George, B Barker, R Richwine, D Baldari, A Alfieri, A Barreto, L Zhang, R Shah, E Hendrix, V Subramaniyam, S Hurley, M Lillestol, M O'Donoghue, S Shayani, E Ryan, R Call, L Zemel, A Chang, A Kivitz, B Freyne, V Bland, K Shore, E Mostel, E Uzoaga, N Andrawis, N Gabra, A Ghitis, K Sabatino, D Browder, S Varma, S Smith, R Fink, GR Aycock, WD Doty, T Alfonso, S Eshaghian, R Karlsberg, S Zarich, C Landau, M McKenzie, R Krause, W Davis, T Haddad, S Voyce, C Alford, J LeDoux, D O'Dea, J Park, V Aroda, A Getaneh, B Graham, R Bhagwat, D Korn, G Ruoff, A Wiseman, I Lieber, J Fialkow, JM Gonzalez-Campoy, C Bayron, B Bertolet, J Lash, C Gerrish, D Robertson, J Rosenfeld, M Seidner, J Agaiby, J Silverfield, D Sugimoto, B Lubin, M Alhaddad, H Lui, G Lakin, S Chokshi, D Donovan, W Felten, S Minton, C Kimmelstiel, J Kuvin, C Still, W Byars, J Talano, V Desai, AJ Bradley, S Baker, M Chane, A Mercado, S Baron, B Harris, N Mayer, M Concha, K Carr, L Chaykin, J Willis, A Clay, E Fenstad, J Furda, P Peterson, M Chang, L Aronne, D Jones, R Prashad, M Benson, R Stegemoller, K Longshaw, J Saleh, W Jennings, R Detweiler, D Viswanath, R Patel, S Lederman, D Weinstein, R Korabathina, V Singh, J Rosen, R Estevez, P Levin, R McNeill, V Kalen, J Reed, R Ashley, L Herman, Y Tsai, D Kayne, A White, I Hussain, L Tami, K Cohen, J Robinson, D Fuchs-Ertman, G Platt, L Belardo, R Reddy, C Rosendorff, F Saba, S Powell, K Anderson, M Abidi, S Rezkalla, A Paraschos, J Wilson, M Moursi, A Shah, V Nadar, L Stonesifer, M Bialow, K Cannon, W Ellison, M Stedman, J Brown, W Harper, KJ Lucas, M DiGiovanna, H Rodbard, M Biscoveanu, C Davis, J Hall, R Littlefield, T Gorman, D Kereiakes, FM Chang, H Tatu, D Cheung, J Kaine, T Knutson, T Logemann, G Pueblitz, J Bianco, B Henson, M Neustel, M Gelernt, W Nelson, K Moriarty, G Lefebvre, K Maw, L Rink, P Behn, H Studdard, G Argoud, T O'Connor, P Krichmar, G Raad, J Pereles-Ortiz, C Sorli, A Cohen, K Pettis, B Cavanaugh, C Phillips, J Wahlen, D Radin, J Rider, E Kosinski, W Leimbach, A Odhav, J Hakas, A Tan, M Howell, D Wombolt, N Fishman, P Shah, P Wylie, C Arauz-Pacheco, A Cavale, A George, R Kroll, J Krantzler, N Tahirkheli, M Jabro, M Newell, P Mullen, N Gencheff, J Meli, K Vora, L Kotek, K Pyzdrowski, H Paez, J Moran, A Tannenbaum, K Deck, R Busch, L Levinson, M Azizad, J Whitaker, B Fox, C Huffman, M Ashraf, J Diogo, R Kushner, J Tallet, V Channamsetty, D Suh, M Atieh, J Navas, V Young, S Shaw, I Dor, B Duffy, P Rubin, D Lewis, W Kaye, R Benton, J Burbano, D Hotchkiss, A Magno, A Alberton, J Collins, O Alvarado, M Stich, S Mahal, J Liu, M Hong, J Dy, B Block, J Lamantia, J Pritchard, M Davis, S Srivastava, S Bilazarian, R Rosario, M McCartney, V Blumberg, R Rajan, E Martin, S Wright, C Brinson, J Johnston, M Graves, M Dominguez, W McKenzie, R Abadier, C Tran, R Castello, E Morawski, J White, F Morris, A Perez, P Trueba, M Sanchez, J Andersen, R Kastelic, J Khan, H Rodriguez, W Izquierdo, A Matias, L Essandoh, C Ince

Publikováno v: Lancet (London, England). 392(10161)

BACKGROUND: There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has been shown to facilitate sustained weight loss in obese or overweight patients. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a4e189e200fa6beb5d4585cfb676ca
https://pubmed.ncbi.nlm.nih.gov/30740430

Chinese Ecstatic Millenarian Folk Religion with Pentecostal Christian Characteristics?

Autor: Daniel H. Bays

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::729b1f3e2af16ce882a7fb4ab1c859d9
https://doi.org/10.1163/9789004342811_004