Zobrazeno 1 - 10
of 20
pro vyhledávání: '"H. B. Younghusband"'
Autor:
D Robb, Elizabeth Dicks, Mark Clendenning, Roger C. Green, Steve Gallinger, Susan Stuckless, Jane Green, Michael O. Woods, Miralem Mrkonjic, C Searle, H B Younghusband, Aaron Pollett, A de la Chapelle, Phillip L. Williams, Amanda T. Dohey, S. N. Thibodeau, Bharati Bapat, M Simms, John R. McLaughlin, Patrick S. Parfrey
Publikováno v:
Gut. 59:1369-1377
Background and aims Colorectal cancer (CRC) is the second most frequent cancer in developed countries. Newfoundland has the highest incidence of CRC in Canada and the highest rate of familial CRC yet reported in the world. To determine the impact of
Publikováno v:
Tissue Antigens. 26:340-343
A mouse monoclonal antibody is described which reacts with HLA-DR4 positive cells. Gel analysis of the immunoprecipitated antigen is consistent with it being a DR molecule.
Autor:
Steve Gallinger, Sharon Buehler, Darshana Daftary, H B Younghusband, John R. McLaughlin, Patrick S. Parfrey, J. D. Robb, Roger C. Green, Jane Green
Publikováno v:
Familial Cancer. 6:53-62
Newfoundland has the highest rate of colorectal cancer (CRC) of any Canadian province. In order to investigate the factors, especially genetic components, responsible for CRC we established the Newfoundland Colorectal Cancer Registry. In a 5-year per
Autor:
L.-T. Deng, W. H. Marshall, D. Codner, J. Gamberg, M. D. Copp, Sheila Drover, H. B. Younghusband, H.-W. Liu
Publikováno v:
Human Immunology. 59:189-197
We have made a panel of murine anti-DP monoclonal antibodies for serological typing of HLA-DP polymorphisms; they can be used in microcytotoxicity (for 7 epitopes) and binding assays (for 8 epitopes). The antibodies detect polymorphic differences in
Autor:
John R. McLaughlin, Darshana Daftary, Jo Knight, Roger C. Green, Miralem Mrkonjic, H. B. Younghusband, Daniel D. Buchanan, Bharati Bapat, Joanne P. Young, S. Gallinger, Aaron Pollett, James B. Rawson, Elizabeth Dicks, Patrick S. Parfrey
Publikováno v:
British Journal of Cancer
Wnt genes encode a large family of secreted glycoproteins with widespread roles in development and carcinogenesis. These proteins have classically been divided into canonical or non-canonical family members based on their ability to activate these di
Publikováno v:
Familial cancer. 4(2)
Hereditary non-polyposis colon cancer (HNPCC) is a significant cause of colorectal and other malignancies. Due to the lack of features that reliably differentiate between a sporadic case and an inherited case of colon cancer, it is likely that HNPCC
Autor:
W. H. Marshall, S. Drover, D. Codner, J. Gamberg, M. D. Copp, H-W. Liu, L. T. Deng, H. B. Younghusband
Publikováno v:
Immunogenetics: Advances and Education ISBN: 9789401063081
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cef4edacc74bc86f608c5070be02c4ed
https://doi.org/10.1007/978-94-011-5486-4_27
https://doi.org/10.1007/978-94-011-5486-4_27
Publikováno v:
Clinical & Investigative Medicine. 31:12
Background: Lynch Syndrome is an autosomal dominant trait that accounts forapproximately 3% of all cases of colorectal cancer (CRC). It is caused by mutations in DNA mismatch repair (MMR) genes, most commonly MLH1 or MSH2. These MMR defects cause hig
Publikováno v:
Familial Cancer; Jun2005, Vol. 4 Issue 2, p169-175, 7p
Publikováno v:
The EMBO Journal. 6:1339-1344
We have previously isolated long-range acting enhancer elements from the HeLa genome by functional selection. In this report, the structural and functional characteristics of one (GA1) of the enhancers are reported. By cloning various restriction fra