Zobrazeno 1 - 10
of 15
pro vyhledávání: '"H. A. van Vugt"'
Autor:
Imre F. Schene, Indi P. Joore, Rurika Oka, Michal Mokry, Anke H. M. van Vugt, Ruben van Boxtel, Hubert P. J. van der Doef, Luc J. W. van der Laan, Monique M. A. Verstegen, Peter M. van Hasselt, Edward E. S. Nieuwenhuis, Sabine A. Fuchs
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Prime editing uses Cas9 nickase fused to a reverse transcriptase to edit genetic information. Here, the authors prime edit primary adult stem cells in 3D organoid cultures to show functional correction of pathogenic mutations without genome-wide off-
Externí odkaz:
https://doaj.org/article/0ba02ae845834a578eb870a005592a64
Autor:
Kelly F. Meijsen, Hugo R. de Jonge, Antje Ballauff, Anke H M van Vugt, Roderick H. J. Houwen, Manuel B Bryant, Thomas Müller, Sabine Middendorp, Tanja Restin, Marcel J. C. Bijvelds, Andreas R. Janecke, Bart G. P. Koot
Publikováno v:
Clinical and Translational Gastroenterology, 12(11):e00427. Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group
INTRODUCTION: Gain-of-function mutations in guanylyl cyclase C (GCC) result in persistent diarrhea with perinatal onset. We investigated a specific GCC inhibitor, SSP2518, for its potential to treat this disorder. METHODS: We investigated the effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3192ebcfb634acea304772d3b318e
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260
Publikováno v:
Diabetic Medicine. WILEY
Diabetic Medicine
Diabetic Medicine
Aims To assess the intended intensity of Type 2 diabetes care and the factors associated with that intensity of care after the annual monitoring visit in which a new person-centred diabetes consultation model including shared decision making was used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2155371379e3bad4fa368c9bda286977
https://hdl.handle.net/1887/122679
https://hdl.handle.net/1887/122679
Publikováno v:
Nederlands tijdschrift voor geneeskunde. 160
Diabetes care is shifting from disease management to personalised care. Internationally, diabetes care providers are advised to integrate the patient's preferences, wishes and possibilities into diabetes care in order to improve its efficiency. The D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0a5e147ae998c430d329fdb9f333ddc
https://pubmed.ncbi.nlm.nih.gov/27405571
https://pubmed.ncbi.nlm.nih.gov/27405571
Publikováno v:
Prostate Cancer and Prostatic Diseases, 13(3), 218-227. Nature Publishing Group
The objective of this study was to determine whether screening for prostate cancer (PC) reduces PC mortality and, if so, whether the required criteria to be introduced as a population-based screening program are satisfied. A literature review was con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2391ce70c019a311aef247816b8b0819
https://pure.eur.nl/en/publications/4df911e4-d494-4fa5-97b3-e249bbf76180
https://pure.eur.nl/en/publications/4df911e4-d494-4fa5-97b3-e249bbf76180
Publikováno v:
International Journal of Human-computer Studies, 67(7), 571-583. Academic Press Inc.
Van Vught, H C, Konijn, E A, Hoorn, J F & Veldhuis, J 2009, ' When too heavy is just fine: Creating trustworthy e-health advisors ', International Journal of Human-computer Studies, vol. 67, no. 7, pp. 571-583 . https://doi.org/10.1016/j.ijhcs.2009.02.005
Van Vught, H C, Konijn, E A, Hoorn, J F & Veldhuis, J 2009, ' When too heavy is just fine: Creating trustworthy e-health advisors ', International Journal of Human-computer Studies, vol. 67, no. 7, pp. 571-583 . https://doi.org/10.1016/j.ijhcs.2009.02.005
In using weight and diet advisors, people compare embodied agents with their actual selves and with the person they want to be: someone with an ideal weight; their ideal selves. In a laboratory and an online experiment, we scrutinized the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046c6481b40decf05dccaf4db3c3ba40
https://research.vu.nl/en/publications/33147024-509d-4777-b7c1-9531aefad1fe
https://research.vu.nl/en/publications/33147024-509d-4777-b7c1-9531aefad1fe
Publikováno v:
van Vugt, H C, Hoorn, J F & Konijn, E A 2009, ' Interactive engagement with embodied agents: An empirically validates framework ', Computer Animation and Virtual Worlds, vol. 20, no. 2/3, pp. 195-204 . https://doi.org/10.1002/cav.312
Computer Animation and Virtual Worlds, 20(2/3), 195-204. John Wiley and Sons Ltd
Computer Animation and Virtual Worlds, 20(2/3), 195-204. John Wiley and Sons Ltd
This paper presents an empirically tested theoretical framework to explain user engagement and end-user satisfaction with interactive agents. Such a framework is not only important from a scientific point of view; application designers may find a set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0de563040792c5f7892357a78ea9182
https://doi.org/10.1002/cav.312
https://doi.org/10.1002/cav.312
Publikováno v:
van Vugt, H C, Konijn, E A, Hoorn, J F, Eliëns, A P W & Keur, I 2007, ' Realism is not all! User engagement with task-related interface characters ', Interacting with Computers, vol. 19, no. 2, pp. 267-280 . https://doi.org/10.1016/j.intcom.2006.08.005
Interacting with Computers, 19(2), 267-280. Oxford University Press
Interacting with Computers, 19(2), 267-280. Oxford University Press
Human-like characters in the interface may evoke social responses in users, and literature suggests that realism is the most important factor herein. However, the effects of interface characters on the user are not well understood. We developed an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649d3288e2676f4a389eae054803a5a2
https://research.vu.nl/en/publications/7b5e9cd1-5905-4a52-8a02-1d403850b892
https://research.vu.nl/en/publications/7b5e9cd1-5905-4a52-8a02-1d403850b892
Autor:
Alfred J. L. G. Pinckers, J.J.M. Janssen, H.J. Winkens, August F. Deutman, B. P. M. Janssen, C.A.G.G. Driessen, Anke H. M. Van Vugt, Leonoor D. Kuhlmann
Publikováno v:
Ophthalmology. 108:1479-1484
Purpose Recent studies show that mutations in the gene encoding 11- cis retinol dehydrogenase are associated with fundus albipunctatus. The authors wanted to investigate whether additional, more severe, mutations in the 11- cis retinol dehydrogenase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e07ee6cb22950f9993919810f906477
https://doi.org/10.1016/s0161-6420(01)00640-6
https://doi.org/10.1016/s0161-6420(01)00640-6
Autor:
F van Bel, J. M. Bakker, Annemieke Kavelaars, Cobi Jacoba Johanna Heijnen, Patrick Joseph Gerardus Hendrikus Kamphuis, Pieter M. Cobelens, H. H. Van Vugt
Publikováno v:
The Journal of Immunology. 165:5932-5937
Major concern has emerged about the possible long term adverse effects of glucocorticoid treatment, which is frequently used for the prevention of chronic lung disease in preterm infants. Here we show that neonatal glucocorticoid treatment of rats in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a87d960d736654aac06de09ec1462af8
https://doi.org/10.4049/jimmunol.165.10.5932
https://doi.org/10.4049/jimmunol.165.10.5932