Zobrazeno 1 - 10
of 85
pro vyhledávání: '"H. A. Schwettman"'
Autor:
George A. Marcus, H. Alan Schwettman
Publikováno v:
The Journal of Physical Chemistry B. 111:3048-3054
We demonstrate the use of transient IR absorption measurements for picosecond thermometry of protein in an aqueous environment. For small temperature changes, measured transient absorption changes are shown to be in excellent agreement with the "stat
Publikováno v:
Journal of Drug Targeting. 15:632-639
Liposomes have tremendous potential for efficient small molecule delivery. Previous studies, however, have been hampered by an inability to monitor their distribution and release of contents. Here, the authors demonstrate the real time monitoring of
Autor:
Josh T. Beckham, Christopher H. Contag, Caitlin E. O'Connell-Rodwell, Weisheng Zhang, E. Duco Jansen, David Shriver, Cameron McClure, Dmitri Simanovskii, Michael Bachmann, H. Alan Schwettman, Yu An Cao, Daniel Palanker
Publikováno v:
The FASEB Journal. 18:264-271
We define five unique cellular responses to thermal stress using a reporter construct generated using the stress-inducible promoter from the gene encoding a murine 70 kDa heat shock protein (Hsp70A.1) to express luciferase (luc). Thermal stress was d
Autor:
A. M. MacLeod, H. A. Schwettman, C.W Rella, Todd I. Smith, D. Oepts, A.F.G. van der Meer, Guido Knippels, W. A. Gillespie, X. Yan
Publikováno v:
Physical Review E, 62, 4216-4220
The detailed shape of picosecond optical pulses from a free-electron laser (FEL) oscillator has been studied for various cavity detunings. For large values of the cavity detuning the optical pulse develops an exponential leading edge, with a time con
Publikováno v:
Chemical Physics Letters. 305:51-56
Experiments are presented on a mixture of tungsten hexacarbonyl (W(CO) 6 ) and (acetylacetonato)dicarbonylrhodium(I) (Rh(CO) 2 acac) in liquid dibutylphthalate (DBP) in which the spectrum of the asymmetric CO stretching modes (∼2000 cm −1 ) is ta
Publikováno v:
The Journal of Physical Chemistry B. 103:557-561
Mid-infrared transient absorption (“pump−probe”) measurements on the amide I band of myoglobin in D2O and in a glass-forming D2O/glycer(ol-d3) solvent mixture reveal very rapid vibrational energy r...
Autor:
Thomas G. Spence, H. A. Schwettman, Eric R. Crosson, P. Haar, Barbara A. Paldus, G. A. Marcus, Richard N. Zare
Publikováno v:
Review of Scientific Instruments. 70:4-10
Pulse stacking, or synchronous pumping, is a novel approach that offers important advantages in cavity ring-down spectroscopy. Using an ultrashort pulse, high repetition rate laser source we have shown that it is possible to resonantly stack pulses i
Publikováno v:
Optics Communications. 157:335-342
We have measured the temporal pulse shape of a mid-infrared free electron laser using a 60 fs Ti:sapphire pulse as an optical gate. By employing a differential technique to simultaneously measure the instantaneous infrared intensity and its time deri
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 144:25-31
We have implemented a control system for the free electron laser (FEL) and its linear accelerator which allows us to produce independently controlled FEL beams multiplexed on a macropulse time scale. In this paper, we discuss the generation of multip
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 144:240-245
We present a method for the remote generation of a transient near-field probe using conventional IR microscopy optics. Photo-induced reflectivity generated by picosecond pulses of visible light incident on the surface of a semiconductor substrate is