Zobrazeno 1 - 10
of 20
pro vyhledávání: '"H. A. Sasame"'
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 18(5)
Four isozymes, designated P-450m50a, P-450m50b, P-450m51a, and P-450m51b, have been isolated from liver microsomes of untreated male CD-1 mice. Electrophoretograms revealed that the molecular weights of P-450m51a and P-450m51b were about 51,000, wher
Autor:
G.L. Gessa, P. Tagliamonte, Jorge Perez-Cruet, H. A. Sasame, Gaetano Di Chiara, Alessandro Tagliamonte
Publikováno v:
Journal of Neurochemistry. 19:1953-1957
— This study has shown that methadone shares with phenothiazine and butyro-phenoneneuroleptics several pharmacological and biochemical actions:thus, D,L-methadone causes catalepsy and hypothermia, blocks apomorphine-induced gnawing, increases brain
Publikováno v:
Journal of the American Chemical Society. 80:5730-5735
Publikováno v:
Journal of Agricultural and Food Chemistry. 9:409-412
Publikováno v:
Journal of the American Chemical Society. 81:6265-6270
Publikováno v:
Journal of the American Chemical Society. 79:4655-4658
Publikováno v:
Archives of Biochemistry and Biophysics. 98:471-478
Two highly purified trypsin inhibitors, designated SBTIA 1 and SBTIA 2 , have been isolated directly from soybean whey solutions by chromatography on DEAE-cellulose. The two inhibitors differ in physical properties, nitrogen content, and trypsin inhi
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 207(3)
Rat lung and liver microsomes mediated the biotransformation of the pulmonary toxin, 4-ipomeanol, to an alkylating metabolite. The enzyme-mediated microsomal alkylation required NADPH and oxygen and was strongly inhibited by carbon monoxide, which in
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 14(5)
A testosterone metabolite, 17 beta-hydroxy-4,6-androstadiene-3-one, possessing an absorbance maximum at 284 nm, was formed during incubation of testosterone with liver microsomes from dexamethasone-treated rats. The metabolite was identified by HPLC,
Publikováno v:
Advances in experimental medicine and biology. 58(00)