Zobrazeno 1 - 10
of 50
pro vyhledávání: '"H. A. M. Willems"'
Autor:
Lisanne M. P. E. van Oppen, Loai K. E. A. Abdelmohsen, Sjenet E. van Emst-de Vries, Pascal L. W. Welzen, Daniela A. Wilson, Jan A. M. Smeitink, Werner J. H. Koopman, Roland Brock, Peter H. G. M. Willems, David S. Williams, Jan C.M. van Hest
Publikováno v:
ACS Central Science, Vol 4, Iss 7, Pp 917-928 (2018)
Externí odkaz:
https://doaj.org/article/2277ffd6f92a4412b7d22285f7c0bf54
Autor:
Marlen Melcher, Katharina Danhauser, Annette Seibt, Özer Degistirici, Fabian Baertling, Arun Kumar Kondadi, Andreas S. Reichert, Werner J. H. Koopman, Peter H. G. M. Willems, Richard J. Rodenburg, Ertan Mayatepek, Roland Meisel, Felix Distelmaier
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-14 (2017)
Abstract Background Disorders of the oxidative phosphorylation (OXPHOS) system represent a large group among the inborn errors of metabolism. The most frequently observed biochemical defect is isolated deficiency of mitochondrial complex I (CI). No e
Externí odkaz:
https://doaj.org/article/09492fc38954469c9353cc31c801a4c5
Autor:
Roel Hammink, Subhra Mandal, Loek J. Eggermont, Marco Nooteboom, Peter H. G. M. Willems, Jurjen Tel, Alan E. Rowan, Carl G. Figdor, Kerstin G. Blank
Publikováno v:
ACS Omega, Vol 2, Iss 3, Pp 937-945 (2017)
Externí odkaz:
https://doaj.org/article/be29adf9c43646e3a07181e117696066
Autor:
Marlies P. Noz, Yvonne A. W. Hartman, Maria T. E. Hopman, Peter H. G. M. Willems, Cees J. Tack, Leo A. B. Joosten, Mihai G. Netea, Dick H. J. Thijssen, Niels P. Riksen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 21 (2019)
Background Low‐grade inflammation, largely mediated by monocyte‐derived macrophages, contributes to atherosclerosis. Sedentary behavior is associated with atherosclerosis and cardiovascular diseases (CVD). We examined whether reducing sedentary b
Externí odkaz:
https://doaj.org/article/57754070194d4d96a7d87226d55f935f
Autor:
Elianne P Bulthuis, Cindy E J Dieteren, Jesper Bergmans, Job Berkhout, Jori A Wagenaars, Els M A van de Westerlo, Emina Podhumljak, Mark A Hink, Laura F B Hesp, Hannah S Rosa, Afshan N Malik, Mariska Kea‐te Lindert, Peter H G M Willems, Han J G E Gardeniers, Wouter K den Otter, Merel J W Adjobo‐Hermans, Werner J H Koopman
Publikováno v:
EMBO Journal, 42
EMBO Journal 42 (2023) 7
EMBO Journal, 42, 7
EMBO Journal, 42(7)
EMBO Journal 42 (2023) 7
EMBO Journal, 42, 7
EMBO Journal, 42(7)
Contains fulltext : 291757.pdf (Publisher’s version ) (Open Access) Macromolecules of various sizes induce crowding of the cellular environment. This crowding impacts on biochemical reactions by increasing solvent viscosity, decreasing the water-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43163eb64ddd4641532f59ef64dc0bbb
https://doi.org/10.15252/embj.2021108533
https://doi.org/10.15252/embj.2021108533
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e114090 (2014)
Opening of the mitochondrial permeability transition pore (mPTP) is involved in various cellular processes including apoptosis induction. Two distinct states of mPTP opening have been identified allowing the transfer of molecules with a molecular wei
Externí odkaz:
https://doaj.org/article/52a5cd44d6bf4a259d5882e2233fb432
Autor:
Julie Nikolaisen, Linn I H Nilsson, Ina K N Pettersen, Peter H G M Willems, James B Lorens, Werner J H Koopman, Karl J Tronstad
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101365 (2014)
Mitochondrial morphology and function are coupled in healthy cells, during pathological conditions and (adaptation to) endogenous and exogenous stress. In this sense mitochondrial shape can range from small globular compartments to complex filamentou
Externí odkaz:
https://doaj.org/article/f9efc8382b7142edb66c873e8a67827a
Autor:
Merel J W, Adjobo-Hermans, Ria, de Haas, Peter H G M, Willems, Aleksandra, Wojtala, Sjenet E, van Emst-de Vries, Jori A, Wagenaars, Mariel, van den Brand, Richard J, Rodenburg, Jan A M, Smeitink, Leo G, Nijtmans, Leonid A, Sazanov, Mariusz R, Wieckowski, Werner J H, Koopman
Publikováno v:
Biochimica et biophysica acta. Bioenergetics. 1861(8)
Mutations in NDUFS4, which encodes an accessory subunit of mitochondrial oxidative phosphorylation (OXPHOS) complex I (CI), induce Leigh syndrome (LS). LS is a poorly understood pediatric disorder featuring brain-specific anomalies and early death. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::17f057b315e2d62d5f878aaa0c00d4c5
https://pubmed.ncbi.nlm.nih.gov/32335026
https://pubmed.ncbi.nlm.nih.gov/32335026
Autor:
Michael Hoffmann, Nadège Bellance, Rodrigue Rossignol, Werner J H Koopman, Peter H G M Willems, Ertan Mayatepek, Olaf Bossinger, Felix Distelmaier
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7644 (2009)
BACKGROUND:Mammalian ATAD3 is a mitochondrial protein, which is thought to play an important role in nucleoid organization. However, its exact function is still unresolved. RESULTS:Here, we characterize the Caenorhabditis elegans (C. elegans) ATAD3 h
Externí odkaz:
https://doaj.org/article/30d7dd560a864819acc3a835078fcd6b
Autor:
Felix Distelmaier, Henk-Jan Visch, Jan A. M. Smeitink, Ertan Mayatepek, Werner J. H. Koopman, Peter H. G. M. Willems
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Malfunction of mitochondrial complex I caused by nuclear gene mutations causes early-onset neurodegenerative diseases. Previous work using cultured fibroblasts of complex-I-deficient patients revealed elevated levels of reactive oxygen species (ROS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6643d682ba9819cdb86501169f6d0247
http://europepmc.org/articles/PMC8496655
http://europepmc.org/articles/PMC8496655