Zobrazeno 1 - 10
of 450
pro vyhledávání: '"H. A. Horst"'
Autor:
Asma Nashawi, Christopher P. Lawson, M. Omar Abdel-Sattar, Joop H. ter Horst, Geoffrey D. Coxon, Alan R. Kennedy
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 76, Iss 7, Pp 1158-1162 (2020)
The structures of two hydroxy-thiophenone derivatives related to the antibiotic thiolactomycin are presented. These are the racemic 3-hydroxy-2,4-dimethyl-2H-thiophen-5-one, C6H8O2S, and 3-hydroxy-4-methyl-2H-thiophen-5-one, C5H6O2S. The main structu
Externí odkaz:
https://doaj.org/article/268c380ecb0d45abbd4f93a43b2d18e2
Publikováno v:
Crystals, Vol 12, Iss 8, p 1102 (2022)
The development of an antisolvent crystallization process requires the construction of an accurate phase diagram for this ternary system of compound, solvent and antisolvent, preferably as a function of temperature. This study gives an efficient meth
Externí odkaz:
https://doaj.org/article/6762d8e5f7f74f03b086409ad00c3e82
Autor:
Stephanie Yerdelen, Yihui Yang, Justin L. Quon, Charles D. Papageorgiou, Chris Mitchell, Ian Houson, Jan Sefcik, Joop H. ter Horst, Alastair J Florence, Cameron J. Brown
Publikováno v:
Crystal Growth & Design. 23:681-693
Publikováno v:
Crystals, Vol 11, Iss 11, p 1344 (2021)
A thorough, systematic study into the effect that structurally related impurities have on both the process and product quality during the crystallization of an active pharmaceutical ingredient is presented. The presence of acetanilide and metacetamol
Externí odkaz:
https://doaj.org/article/6e2bee3b1df34bd7b66e944f4920ba63
Publikováno v:
Crystal Growth & Design. 22:3376-3384
Multicomponent crystals such as co-crystals, salts, and solid solutions can be used to modify physical properties of active pharmaceutical ingredients. Phase diagrams of such multicomponent crystals are essential for crystallization process developme
We demonstrate that several additives and solvents allow switching the polymorphic outcome of solvent mediated phase transformation experiments and crystallization of the antibacterial drug nitrofurantoin. Polymorph β is obtained from most of the so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9600dd6d5c1c4257e2e9701900f58d53
https://doi.org/10.26434/chemrxiv-2022-cdl0z
https://doi.org/10.26434/chemrxiv-2022-cdl0z
Autor:
Maxime D. Charpentier, Raghunath Venkatramanan, Céline Rougeot, Tom Leyssens, Karen Johnston, Joop H. ter Horst
Publikováno v:
Molecular pharmaceutics. 20(1)
Chiral molecules are challenging for the pharmaceutical industry because although physical properties of the enantiomers are the same in achiral systems, they exhibit different effects in chiral systems, such as the human body. The separation of enan
Autor:
Marlus Chorilli, André Luiz Carneiro Soares do Nascimento, Joop H. ter Horst, Flávio Junior Caires, Maxime D. Charpentier, Rafaella de Paula Paseto Fernandes
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2021-06-25T11:15:20Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Engineering and Physical Sciences Research Council Fundação de Ampar
Autor:
Joop H. ter Horst, Paul Tinnemans, Herman J. M. Kramer, Hugo Meekes, René de Gelder, Weiwei Li, Mariëtte de Groen
Publikováno v:
Crystal Growth & Design, 21, 112-124
Crystal Growth & Design, 21, 1, pp. 112-124
Crystal Growth & Design, 21, 1, pp. 112-124
Cocrystallization of racemic-compound-forming chiral molecules can result in conglomerate cocrystals or diastereomerically related cocrystals, which enable the application of chiral separation techniques such as preferential crystallization and class
Autor:
Johannes Hoffmann, James Flannigan, Andrew Cashmore, Maria L. Briuglia, René R. E. Steendam, Charline J. J. Gerard, Mark D. Haw, Jan Sefcik, Joop H. ter Horst
Publikováno v:
Faraday discussions. 235
It is still a challenge to control the formation of particles in industrial crystallization processes. In such processes, new crystals can be generated either by primary or secondary nucleation. While in continuous stirred tank crystallization proces