Zobrazeno 1 - 10
of 33
pro vyhledávání: '"H. A. Drabkin"'
Publikováno v:
Journal of Biological Chemistry. 268:25221-25228
Mutant human initiator tRNA genes carrying changes in each of the three features unique to eukaryotic initiator tRNAs have been constructed, and introduced into CV-1 monkey kidney cells using SV40 virus vectors. The mutant tRNA genes are expressed, a
Autor:
H A Drabkin, D. I. Smith, Larry H. Yamaoka, J. B. Rimmler, Margaret A. Pericak-Vance, Deborah Loeb, Kent W. Small, K J Nunes, Jeffrey M. Stajich, E Whisenant
Publikováno v:
Journal of Medical Genetics. 30:487-491
A genetic map of highly polymorphic microsatellite markers spanning the von Hippel-Lindau region (VHL) of 3p25 was constructed using the CEPH reference pedigrees. A greater than 1000:1 odds map of pter-D3S1038-RAF1-D3S651-D3S656-D3S110- D3S1255-cen w
Autor:
Janan T, Eppig, Carol J, Bult, James A, Kadin, Joel E, Richardson, Judith A, Blake, A, Anagnostopoulos, R M, Baldarelli, M, Baya, J S, Beal, S M, Bello, W J, Boddy, D W, Bradt, D L, Burkart, N E, Butler, J, Campbell, M A, Cassell, L E, Corbani, S L, Cousins, D J, Dahmen, H, Dene, A D, Diehl, H J, Drabkin, K S, Frazer, P, Frost, L H, Glass, C W, Goldsmith, P L, Grant, M, Lennon-Pierce, J, Lewis, I, Lu, L J, Maltais, M, McAndrews-Hill, L, McClellan, D B, Miers, L A, Miller, L, Ni, J E, Ormsby, D, Qi, T B K, Reddy, D J, Reed, B, Richards-Smith, D R, Shaw, R, Sinclair, C L, Smith, P, Szauter, M B, Walker, D O, Walton, L L, Washburn, I T, Witham, Y, Zhu
Publikováno v:
Nucleic Acids Research
The Mouse Genome Database (MGD) forms the core of the Mouse Genome Informatics (MGI) system (http://www.informatics.jax.org), a model organism database resource for the laboratory mouse. MGD provides essential integration of experimental knowledge fo
Autor:
H. A. Drabkin, W. A. Franklin, Roy M. Bremnes, Robert M. Gemmill, Fred R. Hirsch, A. Baron, R. Veve, Lynne T. Bemis, Edward Gabrielson
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 20(10)
PURPOSE: E-cadherin (E-cad) and its associated intracellular molecules, catenins, are critical for intercellular epithelial adhesion and are often expressed in non–small-cell lung carcinomas (NSCLCs). We constructed tissue microarrays (TMAs) to inv
Autor:
R L, Keith, Y E, Miller, R M, Gemmill, H A, Drabkin, E C, Dempsey, T C, Kennedy, S, Prindiville, W A, Franklin
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
Lung carcinogenesis is assumed to be a multistep process, but detailed understanding of the sequential morphological and molecular changes preceding invasive lung cancer remains elusive. To better understand early lung carcinogenesis, we initiated a
Autor:
M, Varella-Garcia, R M, Gemmill, S H, Rabenhorst, A, Lotto, H A, Drabkin, P A, Archer, W A, Franklin
Publikováno v:
Cancer research. 58(20)
Hemizygous deletion in the short (p) arm of chromosome 3 is a common finding in non-small cell lung carcinoma (NSCLC) and is postulated to be a crucial early change in lung tumorigenesis. Yet one of the most frequent nuclear abnormalities in both NSC
Autor:
S K, Grebe, B, McIver, I D, Hay, P S, Wu, L M, Maciel, H A, Drabkin, J R, Goellner, C S, Grant, R B, Jenkins, N L, Eberhardt
Publikováno v:
The Journal of clinical endocrinology and metabolism. 82(11)
Follicular thyroid carcinoma (FTC) exhibits frequent loss of heterozygosity (LOH) on chromosomes 10q and 3p, suggesting involvement of tumor suppressor genes. We screened 14 FTC (10 Hurthle cell carcinomas and 4 nonoxyphilic FTC), 14 papillary thyroi
Autor:
S, Todd, W A, Franklin, M, Varella-Garcia, T, Kennedy, C E, Hilliker, L, Hahner, M, Anderson, J S, Wiest, H A, Drabkin, R M, Gemmill
Publikováno v:
Cancer research. 57(7)
Cytogenetic and loss of heterozygosity (LOH) studies have demonstrated that deletions of chromosome 3p occur at a high frequency in all forms of lung cancer. To clarify the role of 3p in lung tumorigenesis and to more precisely identify targets for p
Publikováno v:
Blood. 88(5)
To study acute myelogenous leukemia 1 (AML1) transcription factor, ETO protein, and t(8;21) AML chimeric AML1/ ETO protein in normal hematopoiesis and in leukemia, we raised rabbit antisera to a bacterially expressed polypeptide containing amino acid
Autor:
H A, Drabkin, P, Erickson
Publikováno v:
Progress in clinical and biological research. 393
Acute leukemia (AL) is a relatively uncommon, but dreaded, complication occurring with increased frequency in individuals with Down syndrome (DS). This selective update includes aspects of AL in DS in which a change or advancement in our understandin