Zobrazeno 1 - 10 of 32 pro vyhledávání: '"H. -O. Keinecke"'
1
Antithrombin III patients with severe sepsis: a pharmacokinetic study
Autor: Johan Decruyenaere, H-O Keinecke, W Ilias, Lg Thijs, H Lignian, W List, H Heinrichs, F Schindel, Sigurd Knaub
Publikováno v: Intensive Care Medicine, 26, 704-715. Springer Verlag
Ilias, W, List, W, Decruyenaere, J, Lignian, H, Knaub, S, Schindel, F, Keinecke, H O, Heinrichs, H & Thijs, L G 2000, ' Antithrombin III patients with severe sepsis: a pharmacokinetic study. ', Intensive Care Medicine, vol. 26, pp. 704-715 . https://doi.org/10.1007/s001340051236
Objectives: To evaluate the safety, pharmacokinetics, and the practicability of two different antithrombin III (AT III) high-dose regimens in patients with severe sepsis.¶Design: Prospective, open, randomized, 2 parallel groups, multinational clinic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3404109dc2c9c2bc427d61fe7c371375
https://hdl.handle.net/1871/25212
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2
Free Papers
Autor: G. Emmanuel, S. Carranza, S. Vettichira, M. Paradis, T. Lie, P. Kessler, V. B. Schini-Kerth, Y. Koh, B. M. Hybertson, E. K. Jepson, M. J. Kim, I. Lee, C. M. Lim, S. D. Lee, W. S. Kim, D. S. Kim, W. D. Kim, J. E. Repine, T. Takeda, T. Yukioka, H. Matsuda, S. Shimazaki, D. Kammermeier, J. Birkmann, L. Blinzler, W. M. Gallmeier, D. Heuser, M. Jourdain, J. Mangalaboyi, O. Carrette, A. Toumoys, F. Fourrier, J. Mizon, C. Chopin, S. L. Peake, J. K. Carter, R. G. Russ, J. Pierides, J. P. Leppard, K. Porter, H. F. Galley, N. R. Webster, S. J. Wigmore, T. S. Walsh, P. Hopton, A. Lee, J. A. Ross, P. A. Majcherczyk, J. Pugin, M. P. Glauser, D. Heumann, G. Zanetti, I. de Werra, A. Sablotzki, I. Welters, T. Menges, G. Görlach, N. Lehmann, G. Hempelmann, E. Giannitsis, I. Tettenborn, U. Stierle, K. Dalhoff, A. Sheikhzadeh, K. W. Diederich, V. Gant, C. Maciver, D. F. Treacher, M. Lamy, L. G. Thijs, B. Eisele, H. -O. Keinecke, H. P. Schuster, F. R. Matthias, W. Oettinger, U. Hartenauer, U. Delvos, S. A. Stott, D. W. Noble, W. Schobersberger, G. Hoffmann, J. Fandrey, G. J. Bellingan, H. Caldwell, I. Dransfield, S. M. Howie, C. Haslett, L. Liaudet, F. Feihl, M. Markert, C. Perret, M. A. Williams, C. Rhoades, S. A. White, J. Miller, S. Withington, A. C. Newland, S. M. Kelsey, A. Froon, M. Bonten, C. Gaillard, J. Greve, P. de Leeuw, M. Drent, E. Stobberingh, W. Buurman, O. Fourcade, M. -F. Simon, F. Leballe, R. Ashraf, L. Sarda, B. Cathala, H. Chap, P. Reper, R. Danckaert, R. Jeunen, T. Bruyns, J. De Hemptinne, A. Vanderkelen
Publikováno v: Intensive Care Medicine. 22:S339-S344
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6da06a7e3fe45a244e212554f0ec276e
https://doi.org/10.1007/bf03216428
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3
C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks--final results of the I.M.P.A.C.T.2 study
Autor: T J, Craig, A K, Bewtra, S L, Bahna, D, Hurewitz, L C, Schneider, R J, Levy, J N, Moy, J, Offenberger, K W, Jacobson, W H, Yang, F, Eidelman, G, Janss, F R, Packer, M A, Rojavin, T, Machnig, H-O, Keinecke, R L, Wasserman
Publikováno v: Allergy. 66(12)
The placebo-controlled study International Multicentre Prospective Angioedema C1-INH Trial 1 (I.M.P.A.C.T.1) demonstrated that 20 U/kg C1 esterase inhibitor (C1-INH) concentrate (Berinert®; CSL Behring, Marburg, Germany) is effective in treating acu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b5b3718272d43b23f73bb63f5445a944
https://pubmed.ncbi.nlm.nih.gov/21884533
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4
Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial
Autor: B L, Warren, A, Eid, P, Singer, S S, Pillay, P, Carl, I, Novak, P, Chalupa, A, Atherstone, I, Pénzes, A, Kübler, S, Knaub, H O, Keinecke, H, Heinrichs, F, Schindel, M, Juers, R C, Bone, S M, Opal
Publikováno v: JAMA. 286(15)
Activation of the coagulation system and depletion of endogenous anticoagulants are frequently found in patients with severe sepsis and septic shock. Diffuse microthrombus formation may induce organ dysfunction and lead to excess mortality in septic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e9c27e3e1ebb39849aaa2961c886425
https://pubmed.ncbi.nlm.nih.gov/11798358
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5
Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis
Autor: H-O Keinecke, Maurice Lamy, H. P. Schuster, U. Delvos, F. R. Matthias, F. Fourrier, L. G. Thijs, H. Heinrichs, B. Eisele
Publikováno v: Intensive care medicine. 24(7)
Objectives: To evaluate the safety and potential efficacy of antithrombin III (AT III) in reducing mortality in patients with severe sepsis. Design: Prospective, randomized, placebo-controlled, double-blind, phase II, multicenter, multinational clini
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b2be27ea16abb557909d1055340ea3
https://pubmed.ncbi.nlm.nih.gov/9722032
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7
Immunomodulation of cimetidine in healthy volunteers
Autor: E. Kreuzfelder, H. O. Keinecke, N. H. Brockmeyer, C. Bluhm, Edgar E. Ohnhaus, E. Scheiermann, G. Shen
Publikováno v: Klinische Wochenschrift. 67(1)
The effect of cimetidine, a histamine H2-receptor antagonist, on the immune system in man was investigated in 11 healthy volunteers. Cimetidine was administered orally in daily doses of 800 mg for a period of 7 days. At the end of the administration
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755d241d0b4b2b014288921248a2abd4
https://pubmed.ncbi.nlm.nih.gov/2522158
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8
Relative and absolute numbers of human lymphocyte subpopulations. A comparison of immunofluorescence microscopy and flow cytometric methodologies with special reference to precision and reference values
Autor: E, Kreuzfelder, G, Shen, U, Rodeck, E, König, W, Luboldt, H O, Keinecke, N, Brockmeyer, N, Scheiermann
Publikováno v: Journal of immunological methods. 97(2)
Lymphocyte subpopulations were determined in blood samples from blood donors (40 women and 45 men) using immunofluorescence microscopy and flow cytometric methodologies. The study demonstrates the value of both methods for the enumeration of lymphocy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5654b2bd60e6e9d336504dfa39b515ff
https://pubmed.ncbi.nlm.nih.gov/3546506
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9
[Age- and sex-dependent changes in human T-lymphocyte subpopulations]
Autor: U, Rodeck, E, Kuwert, H O, Keinecke
Publikováno v: Deutsche medizinische Wochenschrift (1946). 108(49)
Changes in the expression of T-lymphocyte membrane antigens are seen in many diseases, particularly in autoimmune diseases. The reliability of these parameters, as well as their changes associated with age and sex, were examined in 232 healthy subjec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::92cfa0b99850ea5bda73e596adc02b1e
https://pubmed.ncbi.nlm.nih.gov/6606556
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10
The immunomodulatory potency of cimetidine in healthy volunteers
Autor: N H, Brockmeyer, E, Kreuzfelder, N, Chalabi, N, Scheiermann, H O, Keinecke, M, Goos, E E, Ohnhaus
Publikováno v: International journal of clinical pharmacology, therapy, and toxicology. 27(9)
The effect of cimetidine, a histamine H2 receptor antagonist, was investigated in 12 healthy volunteers over a period of six weeks. Cimetidine was administered orally in a daily doses of 1,600 mg during the first three weeks of evaluation. Significan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b22def7ea155f1e05384237df8151708
https://pubmed.ncbi.nlm.nih.gov/2807619
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