Zobrazeno 1 - 10
of 476
pro vyhledávání: '"H. Joly"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The objective of our work was to evaluate the screening of hepatic fibrosis in primary care using the FIB-4 score, automatically calculated. When the FIB-4 was ≥ 1.3, it was defined as positive, and ELF Test was performed. FIB-4 positivity
Externí odkaz:
https://doaj.org/article/efa3e4ba993d4a4a81d7e3b9299e99ef
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-25 (2023)
Abstract Background There is a pressing need for improved methods to identify effective therapeutics for diseases. Many computational approaches have been developed to repurpose existing drugs to meet this need. However, these tools often output long
Externí odkaz:
https://doaj.org/article/c5683b1f35d2401da9e0440268b4fdb6
Autor:
Joseph C. Reynolds, Rochelle W. Lai, Jonathan S. T. Woodhead, James H. Joly, Cameron J. Mitchell, David Cameron-Smith, Ryan Lu, Pinchas Cohen, Nicholas A. Graham, Bérénice A. Benayoun, Troy L. Merry, Changhan Lee
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Exercise has beneficial effects on metabolism and overall physiologic fitness in aged organisms. Here the authors show that MOTS-c is a mitochondrial-encoded exercise-induced peptide that regulates skeletal muscle metabolism and improves healthspan o
Externí odkaz:
https://doaj.org/article/14ed889ddbd64ff7a4d462092a15bb16
Autor:
A. Flores, S. Sandoval-Gonzalez, R. Takahashi, A. Krall, L. Sathe, L. Wei, C. Radu, J. H. Joly, N. A. Graham, H. R. Christofk, W. E. Lowry
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Most tumours are characterized by increased aerobic glycolytic activity. Here the authors show that elevated aerobic glycolysis is not essential for cancer initiation by testing the effect of lactate dehydrogenase depletion on the ability of hair fol
Externí odkaz:
https://doaj.org/article/0d0df205d9034b698c8d903e3a5e6cc5
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 4, p e1008942 (2021)
The metabolic reprogramming of cancer cells creates metabolic vulnerabilities that can be therapeutically targeted. However, our understanding of metabolic dependencies and the pathway crosstalk that creates these vulnerabilities in cancer cells rema
Externí odkaz:
https://doaj.org/article/16c707ccba5e44f7970adc75714ba3cc
Autor:
Alison H. Joly, Yu-Chien Chou, Justin Lesch, Lillian Lee, Stefan Engst, A. Douglas Laird, Andrew You, Jessica Orf, Belinda Cancilla, Frauke Bentzien, Felix Chu, Fawn Qian, Peiwen Yu, Yongchang Shi, Kyoko Yamaguchi, Jenny Tan, Jason Chen, F. Michael Yakes
PDF file - 104KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54cd3621fbfa51d438f48142646da225
https://doi.org/10.1158/1535-7163.22496638.v1
https://doi.org/10.1158/1535-7163.22496638.v1
Autor:
Alison H. Joly, Yu-Chien Chou, Justin Lesch, Lillian Lee, Stefan Engst, A. Douglas Laird, Andrew You, Jessica Orf, Belinda Cancilla, Frauke Bentzien, Felix Chu, Fawn Qian, Peiwen Yu, Yongchang Shi, Kyoko Yamaguchi, Jenny Tan, Jason Chen, F. Michael Yakes
The signaling pathway of the receptor tyrosine kinase MET and its ligand hepatocyte growth factor (HGF) is important for cell growth, survival, and motility and is functionally linked to the signaling pathway of VEGF, which is widely recognized as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c0549987b6953fbcc1b2686b81a276
https://doi.org/10.1158/1535-7163.c.6535348
https://doi.org/10.1158/1535-7163.c.6535348
Akademický článek
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Akademický článek
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Autor:
Alison H. Joly, Joel Greshock, Richard Wooster, Tal Zaks, Wei Xu, Frauke Bentzien, F. Michael Yakes, Julie Lougheed, Danny Tam, Connie Li, Jenny Tan, Tracy Lou, Lillian Mock, Kwang-Ai Won, Peiwen Yu, Kyoko Yamaguchi, Stefan Engst, Fawn Qian
Supplementary Figure 3 from Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777f979469b9592759006bf0b906a39e
https://doi.org/10.1158/0008-5472.22378305.v1
https://doi.org/10.1158/0008-5472.22378305.v1