Zobrazeno 1 - 10
of 2 938
pro vyhledávání: '"H-Ras"'
Autor:
Brain O. Martínez-Esquivel, Miguel A. Baltasar-González, Víctor Corona-Montes, Jorge A. Zamora-Domínguez
Publikováno v:
Revista Médica del Hospital General de México, Vol 87, Iss 3 (2024)
Objective: The aim of this study was to evaluate the effect of the normal and mutated H-RAS gene on genomic instability and apoptosis in MOLT-4 cells. Material and methods: The MOLT-4 cells were cultured and DNA was extracted. Then, the region that c
Externí odkaz:
https://doaj.org/article/f72c0516e1f640669fc0f4594353df92
Akademický článek
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Autor:
Manuel Ramos-Kuri, Sri Harika Meka, Fabio Salamanca-Buentello, Roger J. Hajjar, Larissa Lipskaia, Elie R. Chemaly
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-14 (2021)
Highlights The Ras (Rat Sarcoma) gene family is a group of small G proteins Ras is regulated by growth factors and neurohormones affecting cardiomyocyte growth and hypertrophy Ras directly affects cardiomyocyte physiological and pathological hypertro
Externí odkaz:
https://doaj.org/article/504865b60c394a5b8a209fd43584e51d
Autor:
Frank Hidalgo, Laura M Nocka, Neel H Shah, Kent Gorday, Naomi R Latorraca, Pradeep Bandaru, Sage Templeton, David Lee, Deepti Karandur, Jeffrey G Pelton, Susan Marqusee, David Wemmer, John Kuriyan
Publikováno v:
eLife, Vol 11 (2022)
Cancer mutations in Ras occur predominantly at three hotspots: Gly 12, Gly 13, and Gln 61. Previously, we reported that deep mutagenesis of H-Ras using a bacterial assay identified many other activating mutations (Bandaru et al., 2017). We now show t
Externí odkaz:
https://doaj.org/article/8fa21de2eb884f18b20d8654df44e43f
Autor:
Radoslaw J. Gora, Babette de Jong, Patrick van Hage, Mary Ann Rhiemus, Fjodor van Steenis, John van Noort, Thomas Schmidt, Marcel J. M. Schaaf
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
Developments in single-molecule microscopy (SMM) have enabled imaging individual proteins in biological systems, focusing on the analysis of protein mobility patterns inside cultured cells. In the present study, SMM was applied in vivo, using the zeb
Externí odkaz:
https://doaj.org/article/5a8fe60d05744d6085ec13db31dfaf8a
Autor:
Shuangshuang Wang, Hua Qian, Liwei Zhang, Panpan Liu, Dexuan Zhuang, Qun Zhang, Fuxiang Bai, Zhihong Wang, Yonggan Yan, Jing Guo, Jun Huang, Xunwei Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mutations of H-Ras, a member of the RAS family, are preferentially found in cutaneous squamous cell carcinomas (SCCs). H-Ras has been reported to induce autophagy, which plays an essential role in tissue homeostasis in multiple types of cancer cells
Externí odkaz:
https://doaj.org/article/44a155d9d5634b579840e5a5dcc7cb02
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Sep 01. 115(37), E8624-E8633.
Externí odkaz:
https://www.jstor.org/stable/26531318
Autor:
Yoh, Kathryn E., Regunath, Kausik, Guzman, Asja, Lee, Seung-Min, Pfister, Neil T., Akanni, Olutosin, Kaufman, Laura J., Prives, Carol, Prywes, Ron
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2016 Oct 01. 113(41), E6107-E6116.
Externí odkaz:
https://www.jstor.org/stable/26472044
Publikováno v:
The Journal of Cell Biology, 2001 Mar . 152(6), 1135-1143.
Externí odkaz:
https://www.jstor.org/stable/1620377
Akademický článek
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