Zobrazeno 1 - 10
of 79
pro vyhledávání: '"H-J. Su Huang"'
Autor:
Hiroyuki Nishimori, H.-J. Su Huang, Webster K. Cavenee, Oliver Bogler, Frank B. Furnari, Charles De Smet
Publikováno v:
Journal of Neurochemistry. 81:575-588
The rat glial progenitor cell line CG-4 can be induced to differentiate into either oligodendrocytes or type-2 astrocytes. In order to identify genes whose expression varies coincident with such phenotypic differentiation, we employed representationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32bf5335d1e2357d705d3386c7fd708a
https://doi.org/10.1046/j.1471-4159.2002.00847.x
https://doi.org/10.1046/j.1471-4159.2002.00847.x
Autor:
Kazuhiko Mishima, Manuela Klingler-Hoffmann, Tony Tiganis, Frank B. Furnari, Webster K. Cavenee, H.-J. Su Huang, Michelle Teena Fodero-Tavoletti, Yoshitaka Narita
Publikováno v:
Journal of Biological Chemistry. 276:46313-46318
Glioblastoma multiforme (GBM) is the most aggressive type of glioma and GBMs frequently contain amplifications or mutations of the EGFR gene. The most common mutation results in a truncated receptor tyrosine kinase known as Delta EGFR that signals co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead4812c095dbc2e607d2bfbae5e9a19
https://doi.org/10.1074/jbc.m106571200
https://doi.org/10.1074/jbc.m106571200
Publikováno v:
APOPTOSIS. 6:191-197
Innate and acquired resistance to chemotherapy and radiation therapy has been a major obstacle for clinical oncology. One potential adjunct to such conventional treatments is direct induction of cell death by activation of death receptor-mediated apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::488d4900050da50222a65647566f8f71
https://doi.org/10.1023/a:1011336726649
https://doi.org/10.1023/a:1011336726649
Autor:
Andrew P. Mazar, Webster K. Cavenee, Kazuhiko Mishima, Marilyn Skelly, Xu Dong Wang, Terence R. Jones, Allen M. Gown, H.-J. Su Huang, Xiang-Dong Ji
Publikováno v:
Proceedings of the National Academy of Sciences. 97:8484-8489
The urokinase plasminogen activator system is involved in angiogenesis and tumor growth of malignant gliomas, which are highly neovascularized and so may be amenable to antiangiogenic therapy. In this paper, we describe the activity of Å6, an octam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73ae48d7015a08b7374f065ddaef023b
https://doi.org/10.1073/pnas.150239497
https://doi.org/10.1073/pnas.150239497
Autor:
Richard Yung, Webster K. Cavenee, Oliver Bogler, Virginia W. Sykes, Frank B. Furnari, H.-J. Su Huang, Andrea Kindler-Roehrborn
Publikováno v:
Neuro-Oncology. 2:6-15
Differential display polymerase chain reaction analysis was used to compare five differentiation states of the O-2A progenitor-like cell line CG4: progenitor cells and cells at 12 h or 4 days after the induction of differentiation into oligodendrocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d270d70845e98135bc4397f3433a50f4
https://doi.org/10.1093/neuonc/2.1.6
https://doi.org/10.1093/neuonc/2.1.6
Autor:
Oliver Bögler, Frank B. Furnari, Andrea Kindler-Roehrborn, Virginia W. Sykes, Richard Yung, H.-J. Su Huang, Webster K. Cavenee
Publikováno v:
Neuro-Oncology. 2:6-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0872cdd85bb4127154d2ebcf55cbd8c6
https://doi.org/10.1215/s1522851799000319
https://doi.org/10.1215/s1522851799000319
Autor:
Masao Matsutani, Webster K. Cavenee, H. Nishimori, T. Nakagomi, Takamitsu Fujimaki, Robert M. Nishikawa, H-J. Su Huang
Publikováno v:
Journal of Neuro-Oncology. 46:17-22
The PCAF gene encodes the p300/CBP-Associated Factor (PCAF), a histone acetyltransferase, which regulates p53 by acetylation of Lys320 in the C-terminal portion of p53. While the p53 gene is one of the most frequently mutated tumor suppressor genes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b9e2aef7600ef2b38b3d0042a1c2129
https://doi.org/10.1023/a:1006404110073
https://doi.org/10.1023/a:1006404110073
Publikováno v:
Drug Resistance Updates. 2:30-37
Malignant gliomas are among the most lethal and intractable of human tumors and drug resistance is one of the major obstacles to their successful treatment. Recent advances in the molecular biology and genetics of human cancers provide a detailed und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208f26b8f07029743f0cc7c64e960ecf
https://doi.org/10.1054/drup.1998.0062
https://doi.org/10.1054/drup.1998.0062
Autor:
Gavin P. Robertson, H.-J. Su Huang, Jane W. Fountain, Frank B. Furnari, Tracy G. Lugo, Webster K. Cavenee, Danny R. Welch, Mary E. Miele, Michael J. Glendening
Publikováno v:
Proceedings of the National Academy of Sciences. 95:9418-9423
Gross genetic lesions of chromosome 10 occur in 30–50% of sporadic human melanomas. To test the functional significance of this observation, we have developed an in vitro loss of heterozygosity approach in which a wild-type chromosome 10 was transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145dcf82ad8eb6ee119588dada18970d
https://doi.org/10.1073/pnas.95.16.9418
https://doi.org/10.1073/pnas.95.16.9418
Publikováno v:
Proceedings of the National Academy of Sciences. 94:12479-12484
Deletions of all or part of chromosome 10 are the most common genetic alterations in high-grade gliomas. The PTEN gene (also called MMAC1 and TEP1 ) maps to chromosome region 10q23 and has been implicated as a target of alteration in gliomas and also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5e05b80691d216452c9246f7eba4de
https://doi.org/10.1073/pnas.94.23.12479
https://doi.org/10.1073/pnas.94.23.12479